- Distance: 552.6 km
- Duration: 8h 25m
The bus between Mainz and Prague takes 8h 25m. There is at least one bus per day from Mainz to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Mainz and Prague. The service departs Mainz at 4:20 PM in the afternoon, which arrives into Prague at 00:45:00. All services run direct with no transfers required, and take on average 8h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Frankfurt Central Train Station and arriving at Prague Wilsonova Bus Station. Services depart once daily, and operate every day. The journey takes approximately 8h 25m.
Mainz to Prague bus services, operated by RegioJet, depart from Frankfurt Central Train Station.
Mainz to Prague bus services, operated by RegioJet, arrive at Prague Wilsonova Bus Station.
Book your Mainz to Prague bus tickets online with Omio.
The distance between Mainz and Prague is 438.7 km. The road distance is 541 km.
RegioJet operates a bus from Frankfurt Central Train Station to Prague Wilsonova Bus Station once daily. Tickets cost Kč 750–1,300 and the journey takes 6h 15m.
