The average bus between Mainz and Ulm takes 7h 41m and the fastest bus takes 5h 35m. The bus service runs several times per day from Mainz to Ulm. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Mainz and Ulm. The earliest departure is at 5:10 AM in the morning, and the last departure from Mainz is at 10:15 PM which arrives into Ulm at 5:35 AM. All services require a transfer, and take on average 7h 41m. The schedules shown below are for the next available departures.

12h 10m • 1 change

5h 35m • 1 change
Arrives next day

7h 20m • 1 change

12h 10m • 1 change

5h 35m • 1 change
Arrives next day

7h 20m • 1 change

12h 10m • 1 change

5h 35m • 1 change
Arrives next day

7h 20m • 1 change

12h 10m • 1 change

5h 35m • 1 change
Arrives next day

7h 20m • 1 change
Want to know about travelling from Mainz to Ulm? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Ulm. However, there are services departing from Mainz station and arriving at Ulm station via Ulm. The journey, including transfers, takes approximately 7h 41m.
Mainz to Ulm bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Ulm bus services, operated by FlixBus, arrive at Ulm station.
Book your Mainz to Ulm bus tickets online with FlixBus.
The distance between Mainz and Ulm is 215.8 km. The road distance is 333 km.
FlixBus operates a bus from Frankfurt central train station to Ulm every 4 hours. Tickets cost €21–35 and the journey takes 4h 5m. Karat-S also services this route once daily.