The average train between Mainz and Prague takes 12h 31m and the fastest train takes 12h 11m. The train runs, on average, 2 times per week from Mainz to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice a week between Mainz and Prague. The earliest departure is at 8:34 PM in the evening, and the last departure from Mainz is at 9:14 PM which arrives into Prague at 9:25 AM. All services require a transfer at Frankfurt and take an average of 12h 31m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz station and arriving at Prague station via Leipzig Hbf. The journey, including transfers, takes approximately 12h 31m.
Mainz to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Praha Hlavni Nadrazi station.
Book your Mainz to Prague train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mainz and Prague is 438.7 km. The road distance is 716 km.
You can take a train from Mainz, Römisches Theater to Praha Hlavni Nadrazi via Frankfurt and Leipzig Hbf in around 9h 4m.