The train between Mainz and Prague takes 8h 40m. The train service runs several times per day from Mainz to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Mainz and Prague. The earliest departure is at 8:34 AM in the morning, and the last departure from Mainz is at 12:35 PM which arrives into Prague at 9:15 PM. All services require a transfer at Frankfurt and take an average of 8h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Prague. However, there are services departing from Frankfurt station and arriving at Praha-Holešovice station via Dresden Bahnhof Neustadt station. The journey, including transfers, takes approximately 8h 40m.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Mainz to Prague train services, operated by Danish Railways (DSB), arrive at Praha-Holešovice station.
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The distance between Mainz and Prague is 438.7 km. The road distance is 541 km.
You can take a train from Mainz, Römisches Theater to Praha-Holešovice via Frankfurt and Dresden-Neustadt in around 9h 5m.