COVID-19 Travel restrictions may apply upon entering Czechia. Learn More.
Duration 10h 29m
Distance 542 km
Average price 3 676 Kč
Frequency 4/day

Trip overview

The average train between Mainz and Prague takes 10h 29m and the fastest train takes 8h 53m. The train service runs several times per day from Mainz to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.


  1. Mainz Hbf
  2. Dresden Hbf
  3. Prague
8h 23m
Bookable on Rome2rio
3 044 Kč - 4 425 Kč

Mainz to Prague train times

Trains run four times a day between Mainz and Prague. The earliest departure is at 08:43 in the morning, and the last departure from Mainz is at 18:43 which arrives into Prague at 10:31. All services require a transfer at DRESDEN HBF and take an average of 10h 29m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Mainz to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport?, What is the quickest option?, How much do tickets usually cost? and many more.

There is widespread community transmission globally.
Some travel restrictions are being lifted in Czechia. For the latest travel status, please check the official page for Czechia.

Learn More.

No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz Hbf and arriving at Praha Hlavni Nadrazi via Dresden Hbf. The journey, including transfers, takes approximately 8h 23m.

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The distance between Mainz and Prague is 439 km. The road distance is 542 km.

Get driving directions

Mainz to Prague train services, operated by Deutsche Bahn Intercity-Express, depart from Mainz Hbf station.

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Mainz to Prague train services, operated by Deutsche Bahn Eurocity, arrive at Praha Hlavni Nadrazi station.

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Book your Mainz to Prague train tickets online with Omio and Omio.

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There are 3094+ hotels available in Prague. Prices start at 2 250 Kč per night.

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