Explore 5 ways to travel
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended option
Fly Frankfurt to Prague, subway • 3 h 58 min
$71 - $242
Cheapest option
Bus RegioJet • 9 h 10 min
$32 - $75
5 alternative options
Fly Frankfurt to Dresden, bus • 5 h 36 min
$84 - $277
Train, train to Cologne/Bonn Apt, fly to Prague • 5 h 35 min
$103 - $281
Train • 7 h 37 min
$95 - $147
Bus Eurolines CZ • 8 h 50 min
$41 - $67
Drive • 4 h 55 min
$70 - $110
Questions & Answers
The distance between Mainz and Prague is 439 km. The road distance is 543 km.
The cheapest way to get from Mainz to Prague is to bus which costs 27€ - 65€ and takes 9 h 10 min.
The quickest way to get from Mainz to Prague is to fly and subway which takes 3 h 58 min and costs 60€ - 210€.
No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz-Kastel and arriving at Praha hl.n. (Autobusová St. Wilsonova) via Frankfurt(Main)Hbf and Nürnberg ZOB. The journey, including transfers, takes approximately 7 h 37 min.
It takes approximately 3 h 58 min to get from Mainz to Prague, including transfers.
What companies run services between Mainz, Germany and Prague, Czech Republic?
You can take a train from Mainz to Prague via Frankfurt(Main)Hbf, Nürnberg Hbf, and Nürnberg ZOB in around 7 h 37 min. Alternatively, Eurolines CZ operates a bus from Mainz to Prague once daily. Tickets cost $25 - $45 and the journey takes 7 h 15 min. Eurolines DE also services this route 5 times a week.
- Website
- lufthansa.com
Flights from Frankfurt to Prague
- Ave. Duration
- 1 h
- When
- Every day
- Estimated price
- $100 - $480
Flights from Frankfurt to Prague via Munich
- Ave. Duration
- 2 h 52 min
- When
- Every day
- Estimated price
- $100 - $480
Flights from Frankfurt to Dresden
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $85 - $290
Flights from Frankfurt to Dresden via Munich
- Ave. Duration
- 2 h 43 min
- When
- Every day
- Estimated price
- $85 - $290
Flights from Cologne/Bonn Apt to Prague via Munich
- Ave. Duration
- 2 h 58 min
- When
- Every day
- Estimated price
- $160 - $850
- Website
- csa.cz
Flights from Frankfurt to Prague
- Ave. Duration
- 1 h 20 min
- When
- Every day
- Estimated price
- $60 - $360
- Website
- eurowings.com
Flights from Cologne/Bonn Apt to Prague
- Ave. Duration
- 1 h 10 min
- When
- Every day
- Estimated price
- $40 - $300
- Phone
- 296 19 18 17
- Website
- dpp.cz
Subway from Nádraží Veleslavín to Staroměstská
- Ave. Duration
- 9 min
- Frequency
- Every 15 minutes
- Estimated price
- $1 - $2
- Schedules at
- Prague Public Transit Co.
- Phone
- +49 0180 6 99 66 33
- Website
- bahn.com
Train from Mainz Hbf to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 16 min
- Frequency
- Hourly
- Estimated price
- $13 - $20
- Website
- bahn.de
Train from Frankfurt(M) Flughafen Fernbf to Siegburg/Bonn
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- $35 - $50
- Website
- bahn.de
Train from Frankfurt(Main)Hbf to Nürnberg Hbf
- Ave. Duration
- 2 h 4 min
- Frequency
- Hourly
- Estimated price
- $40 - $60
- Website
- bahn.de
Train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)
- Ave. Duration
- 3 h 35 min
- Frequency
- Every 2 hours
- Estimated price
- $40 - $65
- Website
- bahn.de
- Phone
- +420 542 42 42 42
- info@regiojet.cz
- Website
- regiojet.sk
Bus from Drážďany, Letiště to Praha, ÚAN Florenc
- Ave. Duration
- 2 h 20 min
- Frequency
- Every 4 hours
- Estimated price
- $5 - $8
- Schedules at
- regiojet.sk
Bus from Frankfurt nad Mohanem, Flg.,Terminal 1, Busparkplatz P36 to Praha, ÚAN Florenc
- Ave. Duration
- 7 h 45 min
- Frequency
- 3 times a day
- Estimated price
- $18 - $23
- Schedules at
- regiojet.sk
- info@eurolines.cz
- Website
- elines.cz
Bus from Frankfurt to Praha ÚAN Florenc
- Ave. Duration
- 7 h 15 min
- Frequency
- Once daily
- Estimated price
- $25 - $45
- Schedules at
- elines.cz
- Phone
- +49 6196 2078-501
- service@eurolines.de
- Website
- eurolines.de
Bus from Frankfurt Hbf to Prague Florenc
- Ave. Duration
- 7 h 30 min
- Frequency
- 5 times a week
- Estimated price
- $50 - $75
- Website
- eurolines.de
- Phone
- +49 1807 123 99 123
- info@flixbus.de
- Website
- flixbus.de
Bus from Frankfurt, Frankfurt Airport to Prague, Prague ÚAN Florenc
- Ave. Duration
- 7 h 10 min
- Frequency
- Once daily
- Estimated price
- $40 - $55
- Website
- flixbus.co.uk
Want to know more about travelling around Czechia
Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.