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How to get fromMainz to Pragueby plane, subway, bus, train, or car

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There are 7 ways to get from Mainz to Prague by plane, subway, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Václav Havel Airport Prague, subway

    best
    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    2. Take the subway from Nádraží Veleslavín to Staroměstskásubway subway
    3h 56m
    Kč 1,514–3,681

  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Praguebus bus N1310
    8h 5m
    Kč 1,000–1,800

  3. Bus via Frankfurt am Main

    1. Take the bus from Frankfurt Central Train Station to Prague Florenc Central Bus Stationbus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    7h 57m
    Kč 1,164–1,781

  4. Train via Nuremberg

    1. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    2. Take the train from Nürnberg Hbf to Schwandorftrain train
    3. Take the train from Schwandorf to Praha Hlavni Nadrazitrain train Re
    9h 23m
    Kč 3,414–11,731

  5. Drive 540.6 km

    1. Drive from Mainz to Praguecar car 540.6 km
    4h 35m
    Kč 1,981–2,861

  6. Fly to Dresden Airport, train

    1. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    2. Take the train from Dresden-Neustadt to Praha-Holesovicetrain train
    6h 8m
    Kč 4,316–8,711

  7. Train

    1. Take the train from Frankfurt to Praha Hlavní nádražítrain train Drf
    11h 52m

Mainz to Prague by train and bus

Calendar9Weekly Services
Duration7h 57mAverage Duration
TicketKč 1,164Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Prague.ExpandLaunch map view
  • Distance: 448 km
  • Duration: 3h 56m

What companies run services between Mainz, Germany and Prague, Czechia?

RegioJet operates a bus from Frankfurt Central Train Station to Prague Florenc Central Bus Station once daily. Tickets cost Kč 950–1,400 and the journey takes 6h 18m. Alternatively, you can take a train from Mainz, Römisches Theater to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 23m.

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