There are 7 ways to get from Mainz to Prague by plane, subway, bus, train, night train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Prague, subway  •  3 h 48 min

  1. Fly from Frankfurt (FRA) to Prague (PRG) FRA - PRG
  2. Take the subway from Nádraží Veleslavín to Staroměstská

$71 - $243

Cheapest option

Bus Eurolines CZ  •  8 h 47 min

  1. Take the bus from Frankfurt to Praha ÚAN Florenc

$41 - $68

5 alternative options

Fly to Dresden, bus  •  5 h 31 min

  1. Fly from Frankfurt (FRA) to Dresden (DRS) FRA - DRS
  2. Take the bus from Dresden, Letiště to Prague, ÚAN Florenc

$84 - $278

Train  •  7 h 41 min

  1. Take the train from Frankfurt(Main)Hbf to Nürnberg Hbf Ice / ...
  2. Take the train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)

$106 - $163

Bus Arriva Stredni Cechy  •  8 h 30 min

  1. Take the bus from Frankfurt Flughafen T1 to Praha hl. n. 43490

$42 - $53

Night train  •  9 h 13 min

  1. Take the night train from Frankfurt(M)Hbf Stuttgarter Str. to Praha hl.n. (Autobusová St. Wilsonova)

$106 - $163

Drive  •  4 h 55 min

  1. Drive from Mainz to Prague 339.3 miles

$70 - $110

Questions & Answers

The cheapest way to get from Mainz to Prague is to bus which costs 35€ - 45€ and takes 8 h 30 min.

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The quickest way to get from Mainz to Prague is to fly and subway which costs 60€ - 210€ and takes 3 h 48 min.

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No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz Hbf and arriving at Praha hl.n. (Autobusová St. Wilsonova) via Frankfurt(Main)Hbf and Nürnberg ZOB. The journey, including transfers, takes approximately 7 h 41 min.

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The distance between Mainz and Prague is 439 km. The road distance is 542.8 km.

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The best way to get from Mainz to Prague without a car is to train which takes 7 h 41 min and costs 90€ - 140€.

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It takes approximately 3 h 48 min to get from Mainz to Prague, including transfers.

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Mainz to Prague train services, operated by Deutsche Bahn, depart from Frankfurt(Main)Hbf station.

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The best way to get from Mainz to Prague is to train which takes 7 h 41 min and costs 90€ - 140€. Alternatively, you can bus, which costs 35€ - 45€ and takes 8 h 30 min.

Mode details

The quickest flight from Frankfurt Airport to Prague Airport is the direct flight which takes 1 h.

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Mainz to Prague train services, operated by Deutsche Bahn, arrive at Praha hl.n. (Autobusová St. Wilsonova) station.

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Map of how to get from Mainz to Prague.
Launch map view
  • Distance: 274.2 miles
  • Duration: 3 h 48 min

What companies run services between Mainz, Germany and Prague, Czech Republic?

You can take a train from Mainz to Prague via Frankfurt(Main)Hbf, Nürnberg Hbf, and Nürnberg ZOB in around 7 h 41 min. Alternatively, Arriva Stredni Cechy operates a bus from Mainz to Prague once daily. Tickets cost $28 - $33 and the journey takes 7 h 5 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Prague
Ave. Duration
1 h
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Prague via Munich
Ave. Duration
2 h 52 min
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Dresden
Ave. Duration
55 min
When
Every day
Estimated price
$85 - $290
Flights from Frankfurt to Dresden via Munich
Ave. Duration
2 h 43 min
When
Every day
Estimated price
$85 - $290
CSA
Website
csa.cz
Flights from Frankfurt to Prague
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $360
Train operators
Prague Public Transit Co.
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Frankfurt(Main)Hbf to Nürnberg Hbf
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$50 - $75
Website
bahn.de
Train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
bahn.de
Night train from Frankfurt(M)Hbf Stuttgarter Str. to Praha hl.n. (Autobusová St. Wilsonova)
Ave. Duration
7 h 35 min
Frequency
Once daily
Estimated price
$90 - $140
Website
bahn.de
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Dresden, Letiště to Prague, ÚAN Florenc
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Schedules at
regiojet.sk
Arriva Stredni Cechy
Website
arriva-strednicechy.cz
Bus from Frankfurt Flughafen T1 to Praha hl. n.
Ave. Duration
7 h 5 min
Frequency
Once daily
Estimated price
$28 - $33
Schedules at
arriva.cz
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Frankfurt to Praha ÚAN Florenc
Ave. Duration
7 h 15 min
Frequency
Once daily
Estimated price
$25 - $45
Schedules at
elines.cz
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Frankfurt Hbf to Prague Florenc
Ave. Duration
7 h 30 min
Frequency
5 times a week
Estimated price
$50 - $75
Website
eurolines.de

Want to know more about travelling around Czechia

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More Questions & Answers

Yes, the driving distance between Mainz to Prague is 543 km. It takes approximately 4 h 55 min to drive from Mainz to Prague.

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CSA and Lufthansa offer flights from Frankfurt Airport to Prague Airport.

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There are 3628+ hotels available in Prague. Prices start at $53 USD per night.

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The best way to get from Mainz to Frankfurt Airport is to train which takes 16 min and costs 11€ - 17€.

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