There are 7 ways to get from Mainz to Prague by plane, subway, train, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Václav Havel Airport Prague, subway
best- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the subway from Nádraží Veleslavín to Staroměstskásubway
3h 55mKč 1,828–4,282Bus
cheapest- Take the bus from Mainz central train station to Praguebus N1310
8h 5mKč 600–1,100Train, bus
- Take the train from Mainz, Hauptbahnhof to Dresden Hauptbahnhoftrain 50
- Take the bus from Dresden Bayrische Strasse to Praha, ÚAN Florencbus RegioJet 263
7h 18mKč 1,748–3,384Night train
- Take the night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazinighttrain En
10h 41mKč 3,238–4,629Fly to Dresden Airport, bus
- Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane FRA - DRS
- Take the bus from Dresden Bayrische Strasse to Praha, ÚAN Florencbus
5h 24mKč 3,590–7,592Train
- Take the train from Frankfurt to Nürnberg Hbftrain 41 / ...
- Take the train from Nürnberg Hbf to Schwandorftrain
- Take the train from Schwandorf to Praha Hlavni Nadrazitrain Re
9h 17mKč 2,821–3,956Drive 540.6 km
- Drive from Mainz to Praguecar 540.6 km
4h 36mKč 1,971–2,847
Mainz to Prague by train and bus
Questions & Answers
The cheapest way to get from Mainz to Prague is to bus which costs 600 Kč - 1 100 Kč and takes 8h 5m.
The fastest way to get from Mainz to Prague is to fly and subway which takes 3h 55m and costs 1 800 Kč - 4 300 Kč.
Yes, there is a direct bus departing from Mainz central train station station and arriving at Prague. Services depart once daily, and operate every day. The journey takes approximately 8h 5m.
No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz, Römisches Theater and arriving at Praha Hlavni Nadrazi via Frankfurt(Main)Sued. The journey, including transfers, takes approximately 10h 41m.
The distance between Mainz and Prague is 448 km. The road distance is 540.6 km.
The best way to get from Mainz to Prague without a car is to train and bus which takes 7h 18m and costs 1 700 Kč - 3 400 Kč.
It takes approximately 3h 55m to get from Mainz to Prague, including transfers.
Mainz to Prague bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Prague is to bus which takes 8h 5m and costs 600 Kč - 1 100 Kč. Alternatively, you can train, which costs 2 800 Kč - 4 000 Kč and takes 9h 17m.
What companies run services between Mainz, Germany and Prague, Czechia?
FlixBus operates a bus from Mainz central train station to Prague once daily. Tickets cost Kč 600–1,100 and the journey takes 8h 5m. Alternatively, ÖBB operates a vehicle from Frankfurt(Main)Sued to Praha Hlavni Nadrazi once daily. Tickets cost Kč 3,000–4,300 and the journey takes 8h 57m.
- Website
- lufthansa.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- Kč 1,500–7,500
Flights from Frankfurt to Václav Havel Airport Prague via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- Kč 1,500–6,000
Flights from Frankfurt to Dresden Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- Kč 3,100–6,500
Flights from Frankfurt to Dresden Airport via Munich
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 3,100–6,500
- Website
- condor.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,600–3,500
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- Kč 2,000–7,500
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid.cz
Subway from Nádraží Veleslavín to Staroměstská
- Ave. Duration
- 8 min
- Frequency
- Every 10 minutes
- Estimated price
- Kč 29–40
- Website
- https://pid.cz/en/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Dresden Hauptbahnhof
- Ave. Duration
- 5h 3m
- Frequency
- Every 4 hours
- Estimated price
- Kč 1,600–2,900
- Website
- https://int.bahn.de/en
Train from Frankfurt to Nürnberg Hbf
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- Kč 600–1,400
- Website
- https://int.bahn.de/en
#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
Night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazi
- Ave. Duration
- 8h 57m
- Frequency
- Once daily
- Estimated price
- Kč 3,000–4,300
- Website
- https://www.oebb.at/en/
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Nürnberg Hbf to Schwandorf
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- Kč 400–600
- Website
- https://int.bahn.de/en
- Phone
- 0 89 54 888 97 - 25
- info@laenderbahn.com
- Website
- laenderbahn.com
Train from Schwandorf to Praha Hlavni Nadrazi
- Ave. Duration
- 3h 28m
- Frequency
- Every 4 hours
- Estimated price
- Kč 1,606
- Schedules at
- laenderbahn.com
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- Kč 200–300
- Website
- https://regiojet.com/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 4h 5m
- Frequency
- Hourly
- Estimated price
- Kč 300–550
- Website
- https://www.flixbus.co.uk
Bus from Mainz central train station to Prague
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- Kč 600–1,100
- Website
- https://www.flixbus.co.uk
- Phone
- +359 700 20 544
- Website
- ardatur.bg
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- Kč 290–320
- Website
- https://ardatur.bg/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- Kč 150–220
- Website
- https://union-ivkoni.com/en
Want to know more about travelling around Czechia
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More Questions & Answers
Mainz to Prague bus services, operated by FlixBus, arrive at Prague station.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Nürnberg Hbf station.
Yes, the driving distance between Mainz to Prague is 541 km. It takes approximately 4h 36m to drive from Mainz to Prague.
Book your Mainz to Prague train tickets online with Omio.
Book your Mainz to Prague bus tickets online with Omio and FlixBus.
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