There are 6 ways to get from Mainz to Prague by plane, subway, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, subway
best- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the subway from Nádraží Veleslavín to Staroměstskásubway
2h 46mKč 1,830–4,686Bus
cheapest- Take the bus from Mainz central train station to Praguebus N1310
8h 5mKč 900–1,600Train, bus
- Take the train from Mainz, Hauptbahnhof to Dresden Hauptbahnhoftrain 50
- Take the bus from Dresden Bayrische Strasse to Praha, ÚAN Florencbus RegioJet 263
7h 18mKč 2,613–5,665Drive 540.6 km
- Drive from Mainz to Praguecar 540.6 km
4h 36mKč 2,041–2,948Train via Leipzig
- Take the train from Frankfurt to Leipzig Hbftrain 50 / ...
- Take the train from Leipzig Hbf to Praha Hlavni Nadrazitrain Ec
9h 4mKč 3,418–6,961Train
- Take the train from Frankfurt(Main)Sued to Praha Hlavni Nadrazitrain Ec
10h 41mKč 3,750–6,354
Mainz to Prague by train and bus
Questions & Answers
The cheapest way to get from Mainz to Prague is to bus which costs 900 Kč - 1 600 Kč and takes 8h 5m.
The fastest way to get from Mainz to Prague is to fly and subway which takes 2h 46m and costs 1 800 Kč - 4 700 Kč.
Yes, there is a direct bus departing from Mainz central train station station and arriving at Prague. Services depart once daily, and operate every day. The journey takes approximately 8h 5m.
No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz, Römisches Theater and arriving at Praha Hlavni Nadrazi via Frankfurt and Leipzig Hbf. The journey, including transfers, takes approximately 9h 4m.
The distance between Mainz and Prague is 448 km. The road distance is 540.6 km.
The best way to get from Mainz to Prague without a car is to train and bus which takes 7h 18m and costs 2 600 Kč - 6 000 Kč.
It takes approximately 2h 46m to get from Mainz to Prague, including transfers.
Mainz to Prague bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Prague is to bus which takes 8h 5m and costs 900 Kč - 1 600 Kč. Alternatively, you can train via Leipzig, which costs 3 400 Kč - 7 000 Kč and takes 9h 4m.
What companies run services between Mainz, Germany and Prague, Czechia?
FlixBus operates a bus from Mainz central train station to Prague once daily. Tickets cost Kč 900–1,600 and the journey takes 8h 5m. Alternatively, you can take a train from Mainz, Römisches Theater to Praha Hlavni Nadrazi via Frankfurt and Leipzig Hbf in around 9h 4m.
- Website
- lufthansa.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,500–11,000
- Website
- condor.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- Kč 1,600–4,000
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Tuesday to Sunday
- Estimated price
- Kč 2,200–8,500
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid.cz
Subway from Nádraží Veleslavín to Staroměstská
- Ave. Duration
- 8 min
- Frequency
- Every 10 minutes
- Estimated price
- Kč 29–40
- Website
- https://pid.cz/en/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Dresden Hauptbahnhof
- Ave. Duration
- 5h 3m
- Frequency
- Every 4 hours
- Estimated price
- Kč 2,400–5,500
- Website
- https://int.bahn.de/en
Train from Frankfurt to Leipzig Hbf
- Ave. Duration
- 3h 12m
- Frequency
- Hourly
- Estimated price
- Kč 1,600–3,800
- Website
- https://int.bahn.de/en
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Leipzig Hbf to Praha Hlavni Nadrazi
- Ave. Duration
- 3h 36m
- Frequency
- 4 times a week
- Estimated price
- Kč 1,600–2,800
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Frankfurt(Main)Sued to Praha Hlavni Nadrazi
- Ave. Duration
- 8h 57m
- Frequency
- 3 times a week
- Estimated price
- Kč 3,500–6,000
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- Kč 210–330
- Website
- https://regiojet.com/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 4h 5m
- Frequency
- Hourly
- Estimated price
- Kč 230–400
- Website
- https://www.flixbus.co.uk
Bus from Mainz central train station to Prague
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- Kč 900–1,600
- Website
- https://www.flixbus.co.uk
- Phone
- +359 700 20 544
- Website
- ardatur.bg
Bus from Dresden Bayrische Strasse to Praha, ÚAN Florenc
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- Kč 240–370
- Website
- https://ardatur.bg/en/
Want to know more about travelling around Czechia
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More Questions & Answers
Mainz to Prague bus services, operated by FlixBus, arrive at Prague station.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Leipzig Hbf station.
Yes, the driving distance between Mainz to Prague is 541 km. It takes approximately 4h 36m to drive from Mainz to Prague.
Book your Mainz to Prague bus tickets online with Omio and FlixBus.
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