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How to get fromMainz to Pragueby plane, subway, bus, train, night train, or car

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There are 7 ways to get from Mainz to Prague by plane, subway, bus, train, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Václav Havel Airport Prague, subway

    best
    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    2. Take the subway from Nádraží Veleslavín to Staroměstskásubway subway
    3h 54m
    Kč 1,690–4,982

  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Praguebus bus N1310
    8h 5m
    Kč 900–1,600

  3. Bus via Frankfurt am Main

    1. Take the bus from Frankfurt Central Train Station to Praha, Hlavní Nádražíbus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    7h 58m
    Kč 1,041–1,650

  4. Train

    1. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    2. Take the train from Nürnberg Hbf to Schwandorftrain train
    3. Take the train from Schwandorf to Praha Hlavni Nadrazitrain train Re
    9h 35m
    Kč 3,211–9,300

  5. Night train

    1. Take the night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazinighttrain night train En
    10h 47m
    Kč 3,612–6,410

  6. Fly to Dresden Airport, bus

    1. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    2. Take the bus from Dresden central station to Praha, ÚAN Florencbus bus
    5h 10m
    Kč 3,642–7,812

  7. Drive 540.6 km

    1. Drive from Mainz to Praguecar car 540.6 km
    4h 37m
    Kč 2,045–2,953

Mainz to Prague by train, foot, and bus

Calendar10Weekly Services
Duration7h 58mAverage Duration
TicketKč 1,041Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Prague.ExpandLaunch map view
  • Distance: 447.9 km
  • Duration: 3h 54m

What companies run services between Mainz, Germany and Prague, Czechia?

RegioJet operates a bus from Frankfurt Central Train Station to Praha, Hlavní Nádraží once daily. Tickets cost Kč 850–1,300 and the journey takes 6h 15m. Alternatively, you can take a train from Mainz, Römisches Theater to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 35m.

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