There are 7 ways to get from Mainz to Prague by plane, subway, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Václav Havel Airport Prague, subway
best- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the subway from Nádraží Veleslavín to Staroměstskásubway
3h 54mKč 1,597–3,398Bus via Frankfurt am Main
cheapest- Take the bus from Frankfurt Central Train Station to Prague Wilsonova Bus Stationbus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
7h 53mKč 951–2,090Train via Nuremberg
- Take the train from Frankfurt to Nürnberg Hbftrain 41 / ...
- Take the train from Nürnberg Hbf to Schwandorftrain
- Take the train from Schwandorf to Praha Hlavni Nadrazitrain Re
9h 6mKč 2,891–7,390Drive 540.6 km
- Drive from Mainz to Praguecar 540.6 km
4h 31mKč 2,081–3,006Fly to Dresden Airport, bus
- Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane FRA - DRS
- Take the bus from Dresden to Praha Hlavní nádražíbus
5h 34mKč 4,024–8,518Bus
- Take the bus from Mainz central train station to Praguebus N1310
8h 25mKč 1,100–1,700Train
- Take the train from Frankfurt to Praha Hlavní nádražítrain Drf
11h 51m
Mainz to Prague by train and bus
Comparing Your Travel Options
The cheapest way to get from Mainz to Prague is to bus via Frankfurt am Main which costs 950 Kč - 2 100 Kč and takes 7h 53m.
The fastest way to get from Mainz to Prague is to fly and subway which takes 3h 54m and costs 1 600 Kč - 3 400 Kč.
Yes, there is a direct bus departing from Mainz central train station station and arriving at Prague. Services depart once daily, and operate every day. The journey takes approximately 8h 25m.
No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz, Römisches Theater and arriving at Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf and Schwandorf. The journey, including transfers, takes approximately 9h 6m.
The distance between Mainz and Prague is 448 km. The road distance is 540.6 km.
The best way to get from Mainz to Prague without a car is to bus via Frankfurt am Main which takes 7h 53m and costs 950 Kč - 2 100 Kč.
It takes approximately 3h 54m to get from Mainz to Prague, including transfers.
Mainz to Prague bus services, operated by RegioJet, depart from Frankfurt Central Train Station.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Prague is to bus via Frankfurt am Main which takes 7h 53m and costs 950 Kč - 2 100 Kč. Alternatively, you can train via Nuremberg, which costs 2 800 Kč - 7 500 Kč and takes 9h 6m.
What companies run services between Mainz, Germany and Prague, Czechia?
RegioJet operates a bus from Frankfurt Central Train Station to Prague Wilsonova Bus Station once daily. Tickets cost Kč 750–1,200 and the journey takes 6h 15m. Alternatively, you can take a train from Mainz, Römisches Theater to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 6m.
- Website
- lufthansa.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,400–11,000
Flights from Frankfurt to Václav Havel Airport Prague via Munich
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- Kč 1,400–5,000
Flights from Frankfurt to Dresden Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 3,300–7,500
Flights from Frankfurt to Dresden Airport via Munich
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- Kč 3,300–7,500
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid
Subway from Nádraží Veleslavín to Staroměstská
- Ave. Duration
- 8 min
- Frequency
- Every 10 minutes
- Estimated price
- Kč 29–40
- Website
- pid
- Phone
- +420 222 222 221
- info@regiojet.com
- Website
- RegioJet
Bus from Frankfurt Central Train Station to Prague Wilsonova Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- Kč 750–1,200
- Website
- RegioJet
Want to know more about travelling around Czechia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Mainz to Prague bus services, operated by RegioJet, arrive at Prague Wilsonova Bus Station.
Mainz to Prague train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Nürnberg Hbf station.
Yes, the driving distance between Mainz to Prague is 541 km. It takes approximately 4h 31m to drive from Mainz to Prague.
Book your Mainz to Prague train tickets online with Omio.
Book your Mainz to Prague bus tickets online with Omio.
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