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There are 6 ways to get from Mainz to Prague by plane, subway, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly, subway  •  3 h 45 min

  1. Fly from Frankfurt (FRA) to Prague (PRG) FRA - PRG
  2. Take the subway from Nádraží Veleslavín to Staroměstská

$71 - $242

Cheapest option

Bus Arriva Stredni Cechy  •  8 h 30 min

  1. Take the bus from Frankfurt Flughafen T1 to Praha hl. n. 43490

$41 - $51

4 alternative options

Train  •  8 h 7 min

  1. Take the train from Mainz Hbf to Dresden Hbf Ice
  2. Take the train from Dresden Hbf to Praha hl.n. Ec

$123 - $175

Bus FlixBus  •  8 h 42 min

  1. Take the bus from Frankfurt, Frankfurt central station to Prague, Prague ÚAN Florenc N84 / ...

$45 - $72

Train via Nürnberg Hbf  •  8 h 42 min

  1. Take the train from Mainz Hbf to Nürnberg Hbf Ice / ...
  2. Take the train from Nürnberg Hbf to Schwandorf Re
  3. Take the train from Schwandorf to Praha hl.n. Ex

$107 - $159

Drive  •  4 h 55 min

  1. Drive from Mainz to Prague 339.3 miles

$70 - $110

Questions & Answers

The cheapest way to get from Mainz to Prague is to bus which costs 35€ - 45€ and takes 8 h 30 min.

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The quickest way to get from Mainz to Prague is to fly and subway which costs 60€ - 210€ and takes 3 h 45 min.

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No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz Hbf and arriving at Praha hl.n. via Dresden Hbf. The journey, including transfers, takes approximately 8 h 7 min.

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The distance between Mainz and Prague is 439 km. The road distance is 542.8 km.

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The best way to get from Mainz to Prague without a car is to train which takes 8 h 7 min and costs 100€ - 160€.

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It takes approximately 3 h 45 min to get from Mainz to Prague, including transfers.

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Mainz to Prague train services, operated by Deutsche Bahn, depart from Mainz Hbf station.

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The best way to get from Mainz to Prague is to train which takes 8 h 7 min and costs 100€ - 160€. Alternatively, you can bus, which costs 35€ - 45€ and takes 8 h 30 min.

Mode details

The quickest flight from Frankfurt Airport to Prague Airport is the direct flight which takes 1 h.

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Mainz to Prague train services, operated by Deutsche Bahn, arrive at Praha hl.n. station.

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Map of how to get from Mainz to Prague.
Launch map view
  • Distance: 274.2 miles
  • Duration: 3 h 45 min

What companies run services between Mainz, Germany and Prague, Czech Republic?

You can take a train from Mainz to Prague via Dresden Hbf in around 8 h 7 min. Alternatively, Arriva Stredni Cechy operates a bus from Mainz to Prague once daily. Tickets cost $27 - $32 and the journey takes 7 h 5 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Prague
Ave. Duration
1 h
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Prague via Munich
Ave. Duration
2 h 52 min
When
Every day
Estimated price
$100 - $480
CSA
Website
csa.cz
Flights from Frankfurt to Prague
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $360
Train operators
Prague Public Transit Co.
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mainz Hbf to Dresden Hbf
Ave. Duration
4 h 53 min
Frequency
Every 4 hours
Estimated price
$100 - $150
Website
bahn.de
Train from Dresden Hbf to Praha hl.n.
Ave. Duration
2 h 14 min
Frequency
Every 3 hours
Estimated price
$19 - $28
Website
bahn.de
Train from Mainz Hbf to Nürnberg Hbf
Ave. Duration
2 h 43 min
Frequency
Every 4 hours
Estimated price
$55 - $80
Website
bahn.de
Train from Nürnberg Hbf to Schwandorf
Ave. Duration
1 h 3 min
Frequency
Hourly
Estimated price
$25 - $40
Website
bahn.de
Train from Schwandorf to Praha hl.n.
Ave. Duration
3 h 39 min
Frequency
Every 4 hours
Estimated price
$26 - $40
Website
bahn.de
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Schwandorf to Prague - Main Station
Ave. Duration
3 h 36 min
Frequency
Every 4 hours
Estimated price
$10 - $15
Website
cd.cz
Bus operators
Arriva Stredni Cechy
Website
arriva-strednicechy.cz
Bus from Frankfurt Flughafen T1 to Praha hl. n.
Ave. Duration
7 h 5 min
Frequency
Once daily
Estimated price
$27 - $32
Schedules at
arriva.cz
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Frankfurt, Frankfurt central station to Prague, Prague ÚAN Florenc
Ave. Duration
7 h 10 min
Frequency
Every 4 hours
Estimated price
$29 - $50
Website
flixbus.co.uk

Want to know more about travelling around Czechia

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Mainz to Prague is 543 km. It takes approximately 4 h 55 min to drive from Mainz to Prague.

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CSA and Lufthansa offer flights from Frankfurt Airport to Prague Airport.

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Book your Mainz to Prague train tickets online with Rome2rio.

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There are 3640+ hotels available in Prague. Prices start at $46 USD per night.

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The best way to get from Mainz to Frankfurt Airport is to train which takes 16 min and costs 11€ - 17€.

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