Explore 5 ways to travel

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Frankfurt to Prague, subway  •  3 h 58 min

  1. Fly from Frankfurt (FRA) to Prague (PRG) FRA - PRG
  2. Take the subway from Nádraží Veleslavín to Staroměstská

$71 - $242

Cheapest option

Bus RegioJet  •  9 h 10 min

  1. Take the bus from Frankfurt nad Mohanem, Flg.,Terminal 1, Busparkplatz P36 to Praha, ÚAN Florenc Rj / ...

$32 - $75

5 alternative options

Fly Frankfurt to Dresden, bus  •  5 h 36 min

  1. Fly from Frankfurt (FRA) to Dresden (DRS) FRA - DRS
  2. Take the bus from Drážďany, Letiště to Praha, ÚAN Florenc

$84 - $277

Train, train to Cologne/Bonn Apt, fly to Prague  •  5 h 35 min

  1. Take the train from Mainz Hbf to Frankfurt(M) Flughafen Fernbf
  2. Take the train from Frankfurt(M) Flughafen Fernbf to Siegburg/Bonn
  3. Fly from Cologne/Bonn Apt (CGN) to Prague (PRG) CGN - PRG

$103 - $281

Train  •  7 h 37 min

  1. Take the train from Frankfurt(Main)Hbf to Nürnberg Hbf Ice / ...
  2. Take the train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)

$95 - $147

Bus Eurolines CZ  •  8 h 50 min

  1. Take the bus from Frankfurt to Praha ÚAN Florenc

$41 - $67

Drive  •  4 h 55 min

  1. Drive from Mainz to Prague 339.3 miles

$70 - $110

Questions & Answers

The distance between Mainz and Prague is 439 km. The road distance is 543 km.

The cheapest way to get from Mainz to Prague is to bus which costs 27€ - 65€ and takes 9 h 10 min.

The quickest way to get from Mainz to Prague is to fly and subway which takes 3 h 58 min and costs 60€ - 210€.

No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz-Kastel and arriving at Praha hl.n. (Autobusová St. Wilsonova) via Frankfurt(Main)Hbf and Nürnberg ZOB. The journey, including transfers, takes approximately 7 h 37 min.

It takes approximately 3 h 58 min to get from Mainz to Prague, including transfers.

What companies run services between Mainz, Germany and Prague, Czech Republic?

You can take a train from Mainz to Prague via Frankfurt(Main)Hbf, Nürnberg Hbf, and Nürnberg ZOB in around 7 h 37 min. Alternatively, Eurolines CZ operates a bus from Mainz to Prague once daily. Tickets cost $25 - $45 and the journey takes 7 h 15 min. Eurolines DE also services this route 5 times a week.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Prague
Ave. Duration
1 h
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Prague via Munich
Ave. Duration
2 h 52 min
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Dresden
Ave. Duration
55 min
When
Every day
Estimated price
$85 - $290
Flights from Frankfurt to Dresden via Munich
Ave. Duration
2 h 43 min
When
Every day
Estimated price
$85 - $290
Flights from Cologne/Bonn Apt to Prague via Munich
Ave. Duration
2 h 58 min
When
Every day
Estimated price
$160 - $850
CSA
Website
csa.cz
Flights from Frankfurt to Prague
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $360
Eurowings
Website
eurowings.com
Flights from Cologne/Bonn Apt to Prague
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$40 - $300
Train operators
Prague Public Transit Co.
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mainz Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
16 min
Frequency
Hourly
Estimated price
$13 - $20
Website
bahn.de
Train from Frankfurt(M) Flughafen Fernbf to Siegburg/Bonn
Ave. Duration
37 min
Frequency
Hourly
Estimated price
$35 - $50
Website
bahn.de
Train from Frankfurt(Main)Hbf to Nürnberg Hbf
Ave. Duration
2 h 4 min
Frequency
Hourly
Estimated price
$40 - $60
Website
bahn.de
Train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
bahn.de
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Drážďany, Letiště to Praha, ÚAN Florenc
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Schedules at
regiojet.sk
Bus from Frankfurt nad Mohanem, Flg.,Terminal 1, Busparkplatz P36 to Praha, ÚAN Florenc
Ave. Duration
7 h 45 min
Frequency
3 times a day
Estimated price
$18 - $23
Schedules at
regiojet.sk
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Frankfurt to Praha ÚAN Florenc
Ave. Duration
7 h 15 min
Frequency
Once daily
Estimated price
$25 - $45
Schedules at
elines.cz
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Frankfurt Hbf to Prague Florenc
Ave. Duration
7 h 30 min
Frequency
5 times a week
Estimated price
$50 - $75
Website
eurolines.de
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Frankfurt, Frankfurt Airport to Prague, Prague ÚAN Florenc
Ave. Duration
7 h 10 min
Frequency
Once daily
Estimated price
$40 - $55
Website
flixbus.co.uk

Want to know more about travelling around Czechia

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