The average bus between Prague and Milan takes 13h 54m and the fastest bus takes 13h 11m. The bus service runs several times per day from Prague to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Prague and Milan. The earliest departure is at 4:30 PM in the afternoon, and the last departure from Prague is at 6:20 PM which arrives into Milan at 9:33 AM. All services require a transfer at via omodeo via cechov and take an average of 13h 54m. The schedules shown below are for the next available departures.
Arrives next day

16h 37m • 1 change
Arrives next day

15h 11m • 1 change
Arrives next day

16h 37m • 1 change
Arrives next day

15h 11m • 1 change
Arrives next day

16h 37m • 1 change
Arrives next day

15h 11m • 1 change
Arrives next day

16h 37m • 1 change
Arrives next day

15h 11m • 1 change
Want to know about travelling from Prague to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Milan. However, there are services departing from Prague station and arriving at Milan station via Milan. The journey, including transfers, takes approximately 13h 54m.
Prague to Milan bus services, operated by FlixBus, depart from Prague station.
Prague to Milan bus services, operated by FlixBus, arrive at Milan station.
Book your Prague to Milan bus tickets online with FlixBus and ATM.
The distance between Prague and Milan is 645.5 km. The road distance is 856 km.
FlixBus operates a bus from Prague to Milan twice daily. Tickets cost €70–120 and the journey takes 12h 50m.