Rome2Rio

Brussels to Prague buses

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Trip Overview

The average bus between Brussels and Prague takes 12h 53m and the fastest bus takes 11h 55m. There is at least one bus per day from Brussels to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 53m
Duration
912 km
Distance
Kč 2,200
Average price
Once daily
Frequency

Brussels to Prague bus times

Buses run once daily between Brussels and Prague. The earliest departure is at 8:20 AM in the morning, and the last departure from Brussels is at 6:30 PM which arrives into Prague at 6:25 AM. All services run direct with no transfers required, and take on average 12h 53m. The schedules shown below are for the next available departures.

Departing Tuesday, October 20, 2026

  •  → 

    bus bus 13h 10m • Direct

Departing Wednesday, October 21, 2026

  •  → 

    bus bus 13h 10m • Direct

Departing Thursday, October 22, 2026

  •  → 

    bus bus 13h 10m • Direct
  •  → 

    Arrives next day

    bus bus 11h 55m • Direct

Departing Friday, October 23, 2026

  •  → 

    bus bus 13h 10m • Direct

Departing Saturday, October 24, 2026

  •  → 

    bus bus 13h 10m • Direct

Departing Sunday, October 25, 2026

  •  → 

    bus bus 13h 10m • Direct
  •  → 

    Arrives next day

    bus bus 11h 55m • Direct

Departing Monday, October 26, 2026

  •  → 

    bus bus 13h 10m • Direct

Frequently asked questions

Want to know about travelling from Brussels to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brussels to Prague.ExpandLaunch map view
  • Distance: 911.7 km
  • Duration: 12h 53m

What companies run services between Brussels, Belgium and Prague, Czechia?

FlixBus operates a bus from Brussels-North train station to Praha, ÚAN Florenc 6 times a week. Tickets cost Kč 1,900–2,900 and the journey takes 13h 10m. RegioJet also services this route 4 times a week.

Operators