The average bus between Frederick and St. Louis takes 22h 35m and the fastest bus takes 20h 30m. The bus service runs several times per day from Frederick to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Frederick and St. Louis. The earliest departure is at 8:35 AM in the morning, and the last departure from Frederick is at 7:40 PM which arrives into St. Louis at 3:10 PM. All services require a transfer, and take on average 22h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from Frederick to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frederick to St. Louis. However, there are services departing from Frederick Bus Station and arriving at St Louis Bus Station via Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 22h 35m.
Frederick to St. Louis bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Frederick to St. Louis bus tickets online with Omio and FlixBus.
The distance between Frederick and St. Louis is 1107.2 km. The road distance is 1223 km.
You can take a bus from Frederick Bus Station to St Louis Bus Station via Pittsburgh Intermodal Station in around 18h 20m.
