The average bus between Delaware and St. Louis takes 24h 42m and the fastest bus takes 22h 55m. The bus service runs several times per day from Delaware to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Delaware and St. Louis. The earliest departure is at 10:00 AM in the morning, and the last departure from Delaware is at 9:45 PM which arrives into St. Louis at 11:15 PM. All services require a transfer, and take on average 24h 42m. The schedules shown below are for the next available departures.
Arrives next day

21h 55m • 1 change
Arrives next day

25h 30m • 1 change
Arrives next day

21h 55m • 1 change
Arrives next day

25h 30m • 1 change
Arrives next day

21h 55m • 1 change
Arrives next day

25h 30m • 1 change
Arrives next day

21h 55m • 1 change
Arrives next day

25h 30m • 1 change
Want to know about travelling from Delaware to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Delaware to St. Louis. However, there are services departing from Delaware station and arriving at St. Louis station via Philadelphia Bus Station station. The journey, including transfers, takes approximately 24h 42m.
Delaware to St. Louis bus services, operated by Greyhound USA, depart from Wilmington Bus Station.
Delaware to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Delaware to St. Louis bus tickets online with Greyhound USA.
The distance between Delaware and St. Louis is 1,283.4 km. The road distance is 1,510 km.
You can take a bus from Wilmington Bus Station to St Louis Bus Station via Philadelphia Bus Station in around 22h 35m.