There is widespread community transmission globally.
Some travel restrictions may still be in place within United States. For the latest travel status, please check the official page for United States.
Yes, there is a direct bus departing from Chicago and arriving at St Louis. Services depart once daily, and operate every day. The journey takes approximately 6h 40m.More details
The distance between Chicago and St Louis is 264 miles. The road distance is 298.2 miles.Get driving directions
Chicago to St Louis bus services, operated by Greyhound USA, depart from Chicago station.More details
Chicago to St Louis bus services, operated by Greyhound USA, arrive at St Louis station.More details
Book your Chicago to St Louis bus tickets online with Omio and Busbud.Search and book
There are 592+ hotels available in St Louis. Prices start at $100 USD per night.More details
Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.
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