What is the cheapest way to get from St. Louis to Florida Keys?

The cheapest way to get from St. Louis to Florida Keys is to bus which costs $170 - $430 and takes 30h 55m.

What is the fastest way to get from St. Louis to Florida Keys?

The fastest way to get from St. Louis to Florida Keys is to fly which takes 9h 1m and costs $240 - $900.

Is there a direct bus between St. Louis and Florida Keys?

No, there is no direct bus from St. Louis station to Florida Keys. However, there are services departing from St Louis Bus Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 30h 55m.

How far is it from St. Louis to Florida Keys?

The distance between St. Louis and Florida Keys is 1144 miles. The road distance is 1342.6 miles.

How do I travel from St. Louis to Florida Keys without a car?

The best way to get from St. Louis to Florida Keys without a car is to bus which takes 30h 55m and costs $170 - $430.

How long does it take to get from St. Louis to Florida Keys?

It takes approximately 9h 1m to get from St. Louis to Florida Keys, including transfers.

Where do I catch the St. Louis to Florida Keys bus from?

St. Louis to Florida Keys bus services, operated by Flixbus USA, depart from St Louis Bus Station.

Bus or fly from St. Louis to Florida Keys?

The best way to get from St. Louis to Florida Keys is to fly which takes 9h 1m and costs $240 - $900. Alternatively, you can bus, which costs $170 - $430 and takes 30h 55m.

Where does the St. Louis to Florida Keys bus arrive?

St. Louis to Florida Keys bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.

Can I drive from St. Louis to Florida Keys?

Yes, the driving distance between St. Louis to Florida Keys is 1343 miles. It takes approximately 23h 20m to drive from St. Louis to Florida Keys.

Where can I stay near Florida Keys?

There are 746+ hotels available in Florida Keys.

St. Louis to Florida Keys - 6 ways to travel via plane, bus, car, and shuttle

There are 6 ways to get from St. Louis to Florida Keys by plane, bus (Flixbus, Greyhound), car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Key West International Airport
best
1. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane STL - EYW
9h 1m
$240–896
Bus
cheapest
1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus
3. Take the bus from Miami Airport Station to Big Pine Keybus
30h 55m
$178–421
Drive 1,334.8 mi
1. Drive from St. Louis to Florida Keyscar 1,334.8 mi
23h 20m
$244–352
Fly to Miami International Airport, shuttle
1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane STL - MIA
2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
9h 41m
$494–936
Fly to Fort Lauderdale–Hollywood International Airport, shuttle
1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane STL - FLL
2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
10h 6m
$364–806
Bus via Clarksville Park & Ride
1. Take the bus from St Louis Bus Station to Clarksville Park & Ridebus
2. Take the bus from Clarksville Park & Ride to Atlanta Bus Stationbus
3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus
4. Take the bus from Miami Airport Station to Big Pine Keybus
33h 30m
$197–428

St. Louis to Florida Keys by bus and foot

14Weekly Services

30h 55mAverage Duration

$178Cheapest Price

See schedules

Questions & Answers

Map of how to get from St. Louis to Florida Keys.

Launch map view

Distance: 1,137.2 mi
Duration: 9h 1m

What companies run services between St. Louis, MO, USA and Florida Keys, FL, USA?

American Airlines, Delta, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 30h 55m.

Airlines

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Travelling to the US: What do I need to know?

Rome2Rio’s travel guides to the US tell you the best ways to explore the country, from Amtrak to Greyhound to the New York Subway.

Read the travel guide Travelling to the US: What do I need to know?

Need to know: Greyhound

Rome2Rio’s guide on the bus operator has all the information you need

Read the travel guide Need to know: Greyhound

How to get fromSt. Louis to Florida KeysBy plane, bus (Flixbus, Greyhound), car, shuttle, or bus (Greyhound, Flixbus)

There are 6 ways to get from St. Louis to Florida Keys by plane, bus (Flixbus, Greyhound), car, shuttle, or bus (Greyhound, Flixbus)

Fly to Key West International Airport

Bus

Drive 1,334.8 mi

Fly to Miami International Airport, shuttle

Fly to Fort Lauderdale–Hollywood International Airport, shuttle

Bus via Clarksville Park & Ride