There are 6 ways to get from Cocoa Beach to Florida Keys by car, plane, taxi, train, bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly
best- Drive from Cocoa Beach to Orlando Sanford (SFB)
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)SFB - EYW
5h 27m$113–585Drive 334.3 mi
cheapest- Drive from Cocoa Beach to Florida Keys334.3 mi
6h 26m$61–89Taxi, train, bus
- Take the taxi from Cocoa Beach to Orlando
- Take the train from Orlando to Miami
- Take the bus from Miami Airport Station to Big Pine Key
11h 10m$183–434Line 4 bus to Orlando, fly, bus
- Take the bus from Shepard Park @ Pizza Hut to Transit Center Cocoa East
- Fly from Orlando (MCO) to Key West International Airport (EYW)MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
8h 39m$198–680Taxi, bus (Greyhound)
- Take the taxi from Cocoa Beach to Sebastian
- Take the bus from Sebastian to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
12h 17m$167–215Shuttle, bus
- Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airport
- Take the bus from Orlando RedCoach Station to Miami Airport
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
12h 27m$279–409
Orlando Sanford (SFB) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Cocoa Beach to Florida Keys is to drive which costs $60 - $90 and takes 6h 26m.
The fastest way to get from Cocoa Beach to Florida Keys is to drive and fly which takes 5h 27m and costs $110 - $600.
The distance between Cocoa Beach and Florida Keys is 379 miles. The road distance is 336.2 miles.
The best way to get from Cocoa Beach to Florida Keys without a car is to taxi and train and bus which takes 11h 10m and costs $180 - $440.
It takes approximately 5h 27m to get from Cocoa Beach to Florida Keys, including transfers.
Yes, the driving distance between Cocoa Beach to Florida Keys is 336 miles. It takes approximately 6h 26m to drive from Cocoa Beach to Florida Keys.
There are 112+ hotels available in Florida Keys.
What companies run services between Cocoa Beach, FL, USA and Florida Keys, FL, USA?
There is no direct connection from Cocoa Beach to Florida Keys. However, you can drive to Orlando Sanford (SFB) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the taxi to Orlando, take the train to Miami, walk to Historic Overtown/Lyric Theatre Stat.Rail Northbound, take the line 2600 train to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the bus to Big Pine Key, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 10m
- When
- Thursday and Sunday
- Estimated price
- $55–400
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Phone
- +1 831-539-2901
- guestservices@gobrightline.com
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 34m
- Frequency
- Every 3 hours
- Estimated price
- $15–230
- Book at
- https://www.gobrightline.com
- Smart
- $15–200
- Premium
- $65–230
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
Bus from Sebastian to Miami Airport Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- https://www.greyhound.com/
- Phone
- +1 321-633-1878
- Website
- 321transit.com
Bus from Shepard Park @ Pizza Hut to Transit Center Cocoa East
- Ave. Duration
- 29 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- Space Coast Area Transit
- Phone
- +1 (305) 600-1455
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Melbourne, FL - Mobil Gas to Orlando Airport
- Ave. Duration
- 56 min
- Frequency
- 4 times a day
- Estimated price
- $55–65
- Schedules at
- smartshuttleline.com
- one passenger
- $55–65
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Miami Airport
- Ave. Duration
- 3h 55m
- Frequency
- Every 4 hours
- Estimated price
- $24–80
- Website
- https://www.redcoachusa.com
- Web
- $24–80
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
- Ave. Duration
- 1h
- Estimated price
- $120–180
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide









