There are 6 ways to get from Port Orange to Florida Keys by taxi, plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Orlando Sanford, fly
best- Take the taxi from Port Orange to Orlando-Sanford-Airport-SFBtaxi
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
5h 1m$180–561Bus
cheapest- Take the bus from Daytona Beach to Miami Airport Stationbus FlixBus 2431
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
16h 15m$68–123Taxi, train, bus
- Take the taxi from Port Orange to Delandtaxi
- Take the train from Deland to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
13h 58m$143–245Bus, shuttle
- Take the bus from Daytona Beach to Miami Airport Stationbus FlixBus 2431
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
15h 58m$176–268Drive 395.5 mi
- Drive from Port Orange to Florida Keyscar 395.5 mi
7h 14m$73–105Line 4 bus, line 60 bus, line 34 bus, train to Orlando, fly, bus
- Take the bus from Church ST. & US 1 Ib to Transfer Plazabus
- Take the bus from Transfer Plaza to Amelia Super Stopbus
- Take the bus from Amelia Super Stop to Deland Sunrailbus
- Take the train from DeLand to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
11h 18m$128–392
Port Orange to Florida Keys by bus, tram, shuttle, and foot
Questions & Answers
The cheapest way to get from Port Orange to Florida Keys is to drive which costs $70 - $110 and takes 7h 14m.
The fastest way to get from Port Orange to Florida Keys is to taxi and fly which takes 5h 1m and costs $180 - $600.
No, there is no direct bus from Port Orange to Florida Keys. However, there are services departing from Church ST. & US 1 Ib and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Transfer Plaza, Daytona Beach, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 16h 15m.
The distance between Port Orange and Florida Keys is 351 miles. The road distance is 397.8 miles.
The best way to get from Port Orange to Florida Keys without a car is to taxi and train and bus which takes 13h 58m and costs $140 - $250.
It takes approximately 5h 1m to get from Port Orange to Florida Keys, including transfers.
Port Orange to Florida Keys bus services, operated by Flixbus USA, depart from Daytona Beach station.
Port Orange to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Port Orange to Florida Keys is 398 miles. It takes approximately 7h 14m to drive from Port Orange to Florida Keys.
There are 824+ hotels available in Florida Keys.
What companies run services between Port Orange, FL, USA and Florida Keys, FL, USA?
You can take a bus from Church ST. & US 1 Ib to Florida Keys via Transfer Plaza, Daytona Beach, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 15m.
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 16m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $55–190
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Thursday and Sunday
- Estimated price
- $55–400
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Deland to Miami Amtrak Station
- Ave. Duration
- 7h 6m
- Frequency
- Twice daily
- Estimated price
- $30–100
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 855-724-5411
- info@sunrail.com
- Website
- sunrail.com
Train from DeLand to Sand Lake Road
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- https://sunrail.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Daytona Beach to Miami Airport Station
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a week
- Estimated price
- $40–80
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
- Website
- votran.org
Bus from Church ST. & US 1 Ib to Transfer Plaza
- Ave. Duration
- 27 min
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- votran.org
Bus from Transfer Plaza to Amelia Super Stop
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- votran.org
Bus from Amelia Super Stop to Deland Sunrail
- Ave. Duration
- 28 min
- Frequency
- Every 3 hours
- Estimated price
- $2
- Schedules at
- votran.org
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Ave. Duration
- 44 min
- Estimated price
- $65–95
Daytona Taxi
- Phone
- +1 386-255-5555
- Website
- daytonataxi.com
American Taxi
- Phone
- +1 386-255-0000
- Website
- facebook.com
Daytona Taxi
- Phone
- +1 386-255-5555
- Website
- daytonataxi.com
American Taxi
- Phone
- +1 386-255-0000
- Website
- facebook.com
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