There are 4 ways to get from Isla Mujeres to Florida Keys by ferry, plane, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry to Cancún International Airport, fly to Key West International Airport
best- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Key West International Airport (EYW)plane CUN - EYW
10h 2m$192–616Ferry to Cancún International Airport, fly to Miami International Airport, shuttle
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane CUN - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 43m$327–656Ferry to Cancún International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane CUN - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
11h 11m$317–646Ferry, bus, ferry to Cozumel International Airport, fly to Key West International Airport
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Take the bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turísticabus
- Take the ferry from Playa del Carmen to Cozumelferry
- Fly from Cozumel International Airport (CZM) to Key West International Airport (EYW)plane CZM - EYW
12h 53m$238–976
Cancún International Airport (CUN) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Isla Mujeres to Florida Keys is to ferry and fly which costs $190 - $650 and takes 10h 2m.
The fastest way to get from Isla Mujeres to Florida Keys is to ferry and fly which takes 10h 2m and costs $190 - $650.
The distance between Isla Mujeres and Florida Keys is 465 miles.
It takes approximately 10h 2m to get from Isla Mujeres to Florida Keys, including transfers.
There are 943+ hotels available in Florida Keys.
What companies run services between Isla Mujeres, Mexico and Florida Keys, FL, USA?
There is no direct connection from Isla Mujeres to Florida Keys. However, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, take the shuttle to Big Pine Key, FL, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.
- Website
- aa.com
Flights from Cancún International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $80–450
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $50–310
Flights from Cozumel International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $130–800
Flights from Cozumel International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 8h 37m
- When
- Saturday
- Estimated price
- $270–1,200
- Website
- delta.com
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $140–650
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $50–310
- Website
- aeromexico.com
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $140–650
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $50–310
- Website
- united.com
Flights from Cancún International Airport to Key West International Airport via Houston
- Ave. Duration
- 7h 3m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–700
Flights from Cozumel International Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 8h 11m
- When
- Saturday
- Estimated price
- $380–1,600
- Website
- jetblue.com
Flights from Cancún International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $40–250
- Website
- latam.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 50m
- When
- Friday and Sunday
- Estimated price
- $95–470
- Website
- spirit.com
Flights from Cancún International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $110–310
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +52 55 4386 4652
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turística
- Ave. Duration
- 1h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $11–17
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 997 976 0191
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turística
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $4–6
- Schedules at
- ahorrobus.com.mx
- Phone
- +52 998 460 3084
- servicioalcliente@ultramarferry.com
- Website
- ultramarferry.com
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 4 hours
- Estimated price
- $13–17
- Website
- https://www.ultramarferry.com/en
- Adult
- $17
- Child
- $13
Ferry from Playa del Carmen to Cozumel
- Ave. Duration
- 40 min
- Frequency
- Every 2 hours
- Estimated price
- $6–22
- Website
- https://www.ultramarferry.com/en
- Premium Plus Adult
- $19
- Premium Plus Children
- $14
- Residentes Q.Roo
- $11
- INAPAM
- $6
- First Class Adult
- $22
- First Class Children
- $22
- Phone
- +52 987 872 1588
- info@winjet.mx
- Website
- winjet.mx
Ferry from Playa del Carmen to Cozumel
- Ave. Duration
- 45 min
- Frequency
- Every 3 hours
- Estimated price
- $6–17
- Schedules at
- winjet.mx
- General
- $17
- INAPAM
- $6
- Handicapped
- $6
- Minor
- $12
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