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How to get fromMyrtle Beach to St. Louisby plane, bus (Greyhound, Flixbus), car, or train

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There are 4 ways to get from Myrtle Beach to St. Louis by plane, bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL)plane plane MYR - STL
    2h 49m
    $125–667

  2. Fly to Midamerica St. Louis Airport, train

    cheapest
    1. Fly from Myrtle Beach (MYR) to Midamerica St. Louis Airport (BLV)plane plane MYR - BLV
    2. Take the train from SHILOH-SCOTT station to CIVIC CENTER stationtrain train
    3h 12m
    $103–416

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    20h 31m
    $131–296

  4. Drive 881.1 mi

    1. Drive from Myrtle Beach to St. Louiscar car 881.1 mi
    15h 32m
    $161–233

Myrtle Beach to St. Louis by bus

Calendar7Weekly Buses
Duration20h 31mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to St Louis Bus Station via Atlanta Bus Station in around 20h 31m.

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