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How to get fromMyrtle Beach to St. Louisby plane, bus (Greyhound, Flixbus), car or bus (Flixbus)

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There are 4 ways to get from Myrtle Beach to St. Louis by plane, bus (Greyhound, Flixbus), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL)plane plane MYR - STL
    3h 19m
    $123–665

  2. Bus

    cheapest
    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    20h 35m
    $102–249

  3. Drive 881 mi

    1. Drive from Myrtle Beach to St. Louiscar car 881 mi
    15h 32m
    $161–233

  4. Bus via Columbia

    1. Take the bus from Myrtle Beach, SC to Columbiabus bus
    2. Take the bus from Columbia to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    20h 56m
    $165–389

Myrtle Beach to St. Louis by bus

Calendar7Weekly Buses
Duration20h 35mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to St Louis Bus Station via Atlanta Bus Station in around 20h 35m.

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