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How to get fromMattoon to St. Louisby train, bus or car

Find Transport to St. Louis

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There are 4 ways to get from Mattoon to St. Louis by train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Mattoon Amtrak Station to Champaign-UrbanatrainSaluki / ...
    2. Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus StationbusFlixBus N2521 / ...
    5h 11m
    $34–65
  2. Drive 127.9 mi

    cheapest
    1. Drive from Mattoon to St. Louiscar127.9 mi
    2h 9m
    $24–34
  3. Train, bus via Carbondale

    1. Take the train from Mattoon Amtrak Station to CarbondaletrainSaluki / ...
    2. Take the bus from Carbondale to St. LouisbusAmtrak Thruway Connecting Service
    5h 12m
    $31–62
  4. Train, bus via Bloomington

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain
    2. Take the bus from Champaign Intermodal Trans Ctr to Bloomingtonbus
    3. Take the train from Bloomington-Normal to St. Louistrain
    6h 31m
    $43–120

Mattoon to St. Louis by train and bus

Calendar19Weekly Services
Duration5h 11mAverage Duration
Ticket$34Cheapest Price
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Questions & Answers

What companies run services between Mattoon, IL, USA and St. Louis, MO, USA?

There is no direct connection from Mattoon to St. Louis. However, you can take the train to Champaign-Urbana, walk to Champaign Intermodal Trans Ctr, then take the bus to St Louis Bus Station. Alternatively, you can take a train from Mattoon Amtrak Station to St. Louis via Carbondale and Carbondale in around 5h 12m.

Train operators
Bus operators

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