There are 4 ways to get from Mattoon to St. Louis by train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Mattoon Amtrak Station to Champaign-UrbanaSaluki / ...
- Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus StationFlixBus N2521 / ...
5h 11m$34–65Drive 127.9 mi
cheapest- Drive from Mattoon to St. Louis127.9 mi
2h 9m$24–34Train, bus via Carbondale
- Take the train from Mattoon Amtrak Station to CarbondaleSaluki / ...
- Take the bus from Carbondale to St. LouisAmtrak Thruway Connecting Service
5h 12m$31–62Train, bus via Bloomington
- Take the train from Mattoon Amtrak Station to Champaign-Urbana
- Take the bus from Champaign Intermodal Trans Ctr to Bloomington
- Take the train from Bloomington-Normal to St. Louis
6h 31m$43–120
Mattoon to St. Louis by train and bus
Questions & Answers
The cheapest way to get from Mattoon to St. Louis is to drive which costs $23 - $35 and takes 2h 9m.
The fastest way to get from Mattoon to St. Louis is to drive which takes 2h 9m and costs $23 - $35.
The distance between Mattoon and St. Louis is 229 miles. The road distance is 128.7 miles.
The best way to get from Mattoon to St. Louis without a car is to train and bus which takes 5h 11m and costs $30 - $65.
It takes approximately 5h 11m to get from Mattoon to St. Louis, including transfers.
Yes, the driving distance between Mattoon to St. Louis is 129 miles. It takes approximately 2h 9m to drive from Mattoon to St. Louis.
There are 437+ hotels available in St. Louis.
What companies run services between Mattoon, IL, USA and St. Louis, MO, USA?
There is no direct connection from Mattoon to St. Louis. However, you can take the train to Champaign-Urbana, walk to Champaign Intermodal Trans Ctr, then take the bus to St Louis Bus Station. Alternatively, you can take a train from Mattoon Amtrak Station to St. Louis via Carbondale and Carbondale in around 5h 12m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Mattoon Amtrak Station to Champaign-Urbana
- Ave. Duration
- 51 min
- Frequency
- 3 times a day
- Estimated price
- $3–10
- Website
- https://www.amtrak.com/home.html
Train from Mattoon Amtrak Station to Carbondale
- Ave. Duration
- 2h 12m
- Frequency
- 3 times a day
- Estimated price
- $9–22
- Website
- https://www.amtrak.com/home.html
Train from Bloomington-Normal to St. Louis
- Ave. Duration
- 2h 45m
- Frequency
- 5 times a day
- Estimated price
- $21–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Champaign Intermodal Trans Ctr to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $22–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Champaign Intermodal Trans Ctr to Bloomington
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $18–28
- Website
- https://www.greyhound.com/
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Champaign Intermodal Trans Ctr to Bloomington
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide










