Rome2Rio

How to get fromLouisville to Defianceby bus, taxi, car or plane

Find Transport to Defiance

See all options

There are 4 ways to get from Louisville to Defiance by bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi via Reading

    best
    1. Take the bus from Louisville, KY Bus Station to Greyhound Station Cincinnatibus bus
    2. Take the bus from Cincinnati Bus Station to Allen County Regional Transit Station - Limabus bus
    3. Take the taxi from Allen County Regional Transit Station - Lima to Defiancetaxi taxi
    6h 34m
    $151–250

  2. Drive 264.8 mi

    cheapest
    1. Drive from Louisville to Defiancecar car 264.8 mi
    4h 58m
    $49–70

  3. Fly, taxi

    1. Fly from Louisville International Airport (SDF) to Fort Wayne International Airport (FWA)plane plane SDF - FWA
    2. Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi taxi
    6h 24m
    $212–603

  4. Bus, taxi

    1. Take the bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus bus
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    7h 55m
    $114–213

Louisville International Airport (SDF) to Fort Wayne International Airport (FWA) flights

Calendar83Weekly Planes
Duration5h 19mAverage Duration
Ticket$69Cheapest Price
See schedules

Questions & Answers

What companies run services between Louisville, KY, USA and Defiance, OH, USA?

There is no direct connection from Louisville to Defiance. However, you can take the bus to Greyhound Station Cincinnati, walk to Cincinnati Bus Station, take the bus to Allen County Regional Transit Station - Lima, then take the taxi to Defiance. Alternatively, you can drive from Louisville to Defiance in around 4h 58m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Louisville

Trips to Defiance

Popular routes