There are 13 ways to get from Houston to Defiance by plane, bus, taxi, bus (Flixbus, Amtrak), train, car, bus (Flixbus, Greyhound, Amtrak), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly William P. Hobby Airport to John Glenn Columbus International Airport, bus, taxi
best- Fly from William P. Hobby Airport (HOU) to John Glenn Columbus International Airport (CMH)plane HOU - CMH
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus
- Take the taxi from Delphos to Defiancetaxi
9h 11m$306–1,191Drive 1,169.1 mi
cheapest- Drive from Houston to Defiancecar 1,169.1 mi
19h 58m$214–309Bus
- Take the bus from Downtown Houston to Downtown Dallas / Deep Ellumbus
- Take the bus from Tornado Bus Co - Dallas I-30 to Chicagobus
- Take the bus from Chicago Union Station to Bryan Amtrak Stationbus
28h 33m$305–528Bus, train (Amtrak)
- Take the bus from Houston to Longviewbus
- Take the train from Longview to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bryan Amtrak Stationtrain
29h 49m$462–893Fly William P. Hobby Airport to Indianapolis, bus, taxi
- Fly from William P. Hobby Airport (HOU) to Indianapolis (IND)plane HOU - IND
- Take the bus from Indianapolis, IN to Fort Wayne, INbus
- Take the taxi from Fort Wayne, IN to Defiancetaxi
9h 12m$323–1,129Fly William P. Hobby Airport to Chicago Midway International Airport, train
- Fly from William P. Hobby Airport (HOU) to Chicago Midway International Airport (MDW)plane HOU - MDW
- Take the train from Chicago Union Station to Bryan Amtrak Stationtrain
9h 26m$246–849Fly George Bush Intercontinental Airport to Indianapolis, bus, taxi
- Fly from George Bush Intercontinental Airport (IAH) to Indianapolis (IND)plane IAH - IND
- Take the bus from Indianapolis, IN to Fort Wayne, INbus
- Take the taxi from Fort Wayne, IN to Defiancetaxi
9h 51m$275–882Fly George Bush Intercontinental Airport to John Glenn Columbus International Airport, bus, taxi
- Fly from George Bush Intercontinental Airport (IAH) to John Glenn Columbus International Airport (CMH)plane IAH - CMH
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus
- Take the taxi from Delphos to Defiancetaxi
9h 50m$248–944Fly George Bush Intercontinental Airport to Detroit, bus, train
- Fly from George Bush Intercontinental Airport (IAH) to Detroit (DTW)plane IAH - DTW
- Take the bus from Dearborn to Toledobus
- Take the train from Toledo to Bryan Amtrak Stationtrain
10h 18m$281–361Fly George Bush Intercontinental Airport to Cleveland-Hopkins International Airport, train
- Fly from George Bush Intercontinental Airport (IAH) to Cleveland-Hopkins International Airport (CLE)plane IAH - CLE
- Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain
10h 36m$281–987Fly George Bush Intercontinental Airport to Covington, bus, taxi
- Fly from George Bush Intercontinental Airport (IAH) to Covington (CVG)plane IAH - CVG
- Take the bus from Cincinnati Bus Station to Allen County Regional Transit Station - Limabus
- Take the taxi from Allen County Regional Transit Station - Lima to Defiancetaxi
11h 20m$234–601Bus via New South Memphis
- Take the bus from Downtown Houston to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Union Station to Bryan Amtrak Stationbus
30h 2m$317–523Train (Amtrak)
- Take the train from Houston to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bryan Amtrak Stationtrain
34h 43m$529–1,024
William P. Hobby Airport (HOU) to John Glenn Columbus International Airport (CMH) flights
Questions & Answers
The cheapest way to get from Houston to Defiance is to drive which costs $210 - $310 and takes 19h 58m.
The fastest way to get from Houston to Defiance is to fly and bus and taxi which takes 9h 11m and costs $300 - $1,200.
No, there is no direct bus from Houston to Defiance station. However, there are services departing from Downtown Houston and arriving at Bryan Amtrak Station via Gaston @ Good Latimer - N - Ns, Tornado Bus Co - Dallas I-30, California & 35th Street, LaSalle & 35th Street and Chicago Union Station. The journey, including transfers, takes approximately 28h 33m.
No, there is no direct train from Houston to Defiance station. However, there are services departing from Houston and arriving at Bryan Amtrak Station via New Orleans Union Passenger Terminal and Chicago Union Station. The journey, including transfers, takes approximately 34h 43m.
The distance between Houston and Defiance is 1163 miles. The road distance is 1175.9 miles.
The best way to get from Houston to Defiance without a car is to bus which takes 28h 33m and costs $300 - $550.
It takes approximately 9h 11m to get from Houston to Defiance, including transfers.
Houston to Defiance bus services, operated by Flixbus USA, depart from Downtown Houston station.
Houston to Defiance train services, operated by Amtrak, depart from Houston station.
The best way to get from Houston to Defiance is to bus which takes 28h 33m and costs $300 - $550. Alternatively, you can train, which costs $500 - $1,100 and takes 34h 43m.
What companies run services between Houston, TX, USA and Defiance, OH, USA?
You can take a bus from Downtown Houston to Defiance via Downtown Dallas / Deep Ellum, Gaston @ Good Latimer - N - Ns, Samuell @ Cinnabar - E - Ns, Tornado Bus Co - Dallas I-30, California & 35th Street, Sox-35th Red Line Station, LaSalle & 35th Street, Clark & Harrison, Chicago Union Station, and Bryan Amtrak Station in around 28h 33m. Alternatively, you can take a train from Houston to Defiance via New Orleans Union Passenger Terminal, Chicago Union Station, and Bryan Amtrak Station in around 34h 43m.
- Website
- southwest.com
Flights from William P. Hobby Airport to John Glenn Columbus International Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $210–1,000
Flights from William P. Hobby Airport to John Glenn Columbus International Airport via Nashville
- Ave. Duration
- 4h 7m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $210–1,000
Flights from William P. Hobby Airport to John Glenn Columbus International Airport via St. Louis
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,100
Flights from William P. Hobby Airport to John Glenn Columbus International Airport via Dallas
- Ave. Duration
- 4h 27m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,100
Flights from William P. Hobby Airport to John Glenn Columbus International Airport via Atlanta
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $230–1,100
Flights from William P. Hobby Airport to John Glenn Columbus International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $240–1,100
Flights from William P. Hobby Airport to Indianapolis
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $180–900
Flights from William P. Hobby Airport to Indianapolis via Nashville
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $190–950
Flights from William P. Hobby Airport to Indianapolis via Dallas
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $200–950
Flights from William P. Hobby Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 35m
- When
- Tuesday to Friday
- Estimated price
- $220–1,000
Flights from William P. Hobby Airport to Indianapolis via Atlanta
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,100
Flights from William P. Hobby Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $130–650
Flights from William P. Hobby Airport to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 3h 55m
- When
- Tuesday and Wednesday
- Estimated price
- $130–650
Flights from William P. Hobby Airport to Chicago Midway International Airport via Dallas
- Ave. Duration
- 4h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $140–700
Flights from William P. Hobby Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday to Friday
- Estimated price
- $140–700
- Website
- delta.com
Flights from George Bush Intercontinental Airport to Indianapolis via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $160–750
Flights from George Bush Intercontinental Airport to Indianapolis via Detroit
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $180–800
Flights from George Bush Intercontinental Airport to John Glenn Columbus International Airport via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $170–800
Flights from George Bush Intercontinental Airport to John Glenn Columbus International Airport via Detroit
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $180–850
Flights from George Bush Intercontinental Airport to Detroit
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $140–650
Flights from George Bush Intercontinental Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $180–850
Flights from George Bush Intercontinental Airport to Cleveland-Hopkins International Airport via Atlanta
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $180–850
Flights from George Bush Intercontinental Airport to Covington via Atlanta
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $160–800
Flights from George Bush Intercontinental Airport to Covington via Detroit
- Ave. Duration
- 5h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–900
- Website
- united.com
Flights from George Bush Intercontinental Airport to Indianapolis
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- $130–650
Flights from George Bush Intercontinental Airport to John Glenn Columbus International Airport
- Ave. Duration
- 2h 46m
- When
- Every day
- Estimated price
- $150–750
Flights from George Bush Intercontinental Airport to Detroit
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- $140–650
Flights from George Bush Intercontinental Airport to Cleveland-Hopkins International Airport
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $170–800
Flights from George Bush Intercontinental Airport to Covington
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- $140–750
- Website
- aa.com
Flights from George Bush Intercontinental Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $140–700
Flights from George Bush Intercontinental Airport to Cleveland-Hopkins International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $190–850
Flights from George Bush Intercontinental Airport to Cleveland-Hopkins International Airport via Charlotte
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $200–900
Flights from George Bush Intercontinental Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $160–800
- Website
- flyfrontier.com
Flights from George Bush Intercontinental Airport to John Glenn Columbus International Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $220–800
Flights from George Bush Intercontinental Airport to Detroit
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $180–210
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Longview to Chicago Union Station
- Ave. Duration
- 19h 31m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Train from Toledo to Bryan Amtrak Station
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- https://www.amtrak.com/home.html
Train from Cleveland Amtrak to Bryan Amtrak Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $50–110
- Website
- https://www.amtrak.com/home.html
Train from Houston to New Orleans Union Passenger Terminal
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a week
- Estimated price
- $110–240
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Chicago Union Station
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- $300–600
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
Bus from Indianapolis, IN to Fort Wayne, IN
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- https://baronsbus.com
Bus from Indianapolis, IN to Fort Wayne, IN
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- https://baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 888 954 6287
- gobus@hapcap.org
- Website
- ridegobus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://ridegobus.com
- Book at
- https://booking.ridegobus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://ridegobus.com
- Book at
- https://booking.ridegobus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Downtown Houston to Downtown Dallas / Deep Ellum
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–60
- Schedules at
- flixbus.com
Bus from Downtown Houston to Memphis Bus Station
- Ave. Duration
- 14h 30m
- Frequency
- 5 times a week
- Estimated price
- $110–200
- Schedules at
- flixbus.com
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Once daily
- Estimated price
- $80–140
- Schedules at
- flixbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Dallas I-30 to Chicago
- Ave. Duration
- 16h 15m
- Frequency
- Once daily
- Estimated price
- $140–290
- Schedules at
- tornadobus.com
- Adults 11-59
- $140–290
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Once a week
- Estimated price
- $65–100
- Website
- https://www.amtrak.com/home.html
Bus from Houston to Longview
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- https://www.amtrak.com/home.html
Bus from Dearborn to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- https://www.amtrak.com/home.html
Bus from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Once a week
- Estimated price
- $65–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Cincinnati Bus Station to Allen County Regional Transit Station - Lima
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
- Ave. Duration
- 1h 1m
- Estimated price
- $85–160
Black and White Transportation
- Phone
- +1-419-536-8294
- Website
- bwtransportation.com
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Black and White Transportation
- Phone
- +1-419-536-8294
- Website
- bwtransportation.com
Black and White Transportation
- Phone
- +1-419-536-8294
- Website
- bwtransportation.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Houston to Defiance bus services, operated by Flixbus USA, arrive at Downtown Dallas / Deep Ellum station.
Defiance is 1h ahead of Houston. It is currently 10:41 AM in Houston and 11:41 AM in Defiance.
Houston to Defiance train services, operated by Amtrak, arrive at New Orleans Union Passenger Terminal station.
Yes, the driving distance between Houston to Defiance is 1176 miles. It takes approximately 19h 58m to drive from Houston to Defiance.
There are 10+ hotels available in Defiance.
















