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How to get fromHouston to Defianceby plane, bus, taxi, bus (Amtrak), train, car, bus (Flixbus, Greyhound, Amtrak), or train (Amtrak)

Find Transport to Defiance

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There are 13 ways to get from Houston to Defiance by plane, bus, taxi, bus (Amtrak), train, car, bus (Flixbus, Greyhound, Amtrak), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly William P. Hobby Airport to John Glenn Columbus International Airport, bus, taxi

    best
    1. Fly from William P. Hobby Airport (HOU) to John Glenn Columbus International Airport (CMH)plane plane HOU - CMH
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    9h 12m
    $256–991

  2. Drive  1,169.1 mi

    cheapest
    1. Drive from Houston to Defiancecar car 1,169.1 mi
    19h 58m
    $214–309

  3. Bus

    1. Take the bus from Houston, TX - 808 Jefferson St to Dallas, TX - 1376 Marilla Stbus bus
    2. Take the bus from Dallas Jefferson to Chicagobus bus
    3. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus
    29h 26m
    $374–450

  4. Bus, train (Amtrak)

    1. Take the bus from Houston to Longviewbus bus
    2. Take the train from Longview to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    29h 49m
    $373–747

  5. Fly William P. Hobby Airport to Indianapolis, bus, taxi

    1. Fly from William P. Hobby Airport (HOU) to Indianapolis (IND)plane plane HOU - IND
    2. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    3. Take the taxi from Fort Wayne, IN to Defiancetaxi taxi
    9h 12m
    $293–1,025

  6. Fly William P. Hobby Airport to Chicago Midway International Airport, train

    1. Fly from William P. Hobby Airport (HOU) to Chicago Midway International Airport (MDW)plane plane HOU - MDW
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    9h 30m
    $216–739

  7. Fly George Bush Intercontinental Airport to Indianapolis, bus, taxi

    1. Fly from George Bush Intercontinental Airport (IAH) to Indianapolis (IND)plane plane IAH - IND
    2. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    3. Take the taxi from Fort Wayne, IN to Defiancetaxi taxi
    9h 52m
    $265–878

  8. Fly George Bush Intercontinental Airport to John Glenn Columbus International Airport, bus, taxi

    1. Fly from George Bush Intercontinental Airport (IAH) to John Glenn Columbus International Airport (CMH)plane plane IAH - CMH
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    9h 57m
    $268–604

  9. Fly George Bush Intercontinental Airport to Detroit, bus, train

    1. Fly from George Bush Intercontinental Airport (IAH) to Detroit (DTW)plane plane IAH - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    10h 18m
    $231–458

  10. Fly George Bush Intercontinental Airport to Cleveland-Hopkins International Airport, train

    1. Fly from George Bush Intercontinental Airport (IAH) to Cleveland-Hopkins International Airport (CLE)plane plane IAH - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    10h 35m
    $231–432

  11. Fly George Bush Intercontinental Airport to Covington, bus, taxi

    1. Fly from George Bush Intercontinental Airport (IAH) to Covington (CVG)plane plane IAH - CVG
    2. Take the bus from Cincinnati Bus Station to Lima Regional Transit Authoritybus bus
    3. Take the taxi from Lima Regional Transit Authority to Defiancetaxi taxi
    11h 10m
    $235–596

  12. Bus via New South Memphis

    1. Take the bus from Downtown Houston to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus
    30h 2m
    $297–459

  13. Train (Amtrak)

    1. Take the train from Houston to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    34h 43m
    $434–938

William P. Hobby Airport (HOU) to John Glenn Columbus International Airport (CMH) flights

Calendar53Weekly Planes
Duration4h 18mAverage Duration
Ticket$166Cheapest Price
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Comparing Your Travel Options

Map of how to get from Houston to Defiance.ExpandLaunch map view
  • Distance: 1,156.6 mi
  • Duration: 9h 12m

What companies run services between Houston, TX, USA and Defiance, OH, USA?

You can take a bus from Houston, TX - 808 Jefferson St to Defiance via Dallas, TX - 1376 Marilla St, Houston @ Young - S - Mb, Jefferson @ Marsalis - W - Ns, Dallas Jefferson, California & 35th Street, Sox-35th Red Line Station, LaSalle & 35th Street, Clark & Harrison, Chicago Union Station, and Bryan Amtrak Station in around 29h 26m. Alternatively, you can take a train from Houston to Defiance via New Orleans Union Passenger Terminal, Chicago Union Station, and Bryan Amtrak Station in around 34h 43m.

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