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How to get fromBuffalo to Defianceby bus, train, train (Amtrak), car, plane or taxi

Find Transport to Defiance

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There are 4 ways to get from Buffalo to Defiance by bus, train, train (Amtrak), car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Toledo Bus Stopbus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    8h 20m
    $122–205

  2. Drive 339.1 mi

    cheapest
    1. Drive from Buffalo to Defiancecar car 339.1 mi
    6h 20m
    $62–90

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    8h 31m
    $159–365

  4. Fly, taxi

    1. Fly from Buffalo Niagara International Airport (BUF) to Fort Wayne International Airport (FWA)plane plane BUF - FWA
    2. Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi taxi
    6h 30m
    $226–758

Buffalo Niagara International Airport (BUF) to Fort Wayne International Airport (FWA) flights

Calendar94Weekly Planes
Duration5h 35mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Defiance, OH, USA?

Amtrak operates a train from Buffalo Depew Station to Bryan Amtrak Station twice daily. Tickets cost $95–220 and the journey takes 6h 44m.

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