What is the cheapest way to get from Buffalo to Defiance?

The cheapest way to get from Buffalo to Defiance is to drive which costs $60 - $95 and takes 5h 58m.

What is the fastest way to get from Buffalo to Defiance?

The fastest way to get from Buffalo to Defiance is to drive which takes 5h 58m and costs $60 - $95.

How far is it from Buffalo to Defiance?

The distance between Buffalo and Defiance is 376 miles. The road distance is 348.7 miles.

How do I travel from Buffalo to Defiance without a car?

The best way to get from Buffalo to Defiance without a car is to train which takes 8h 31m and costs $95 - $280.

How long does it take to get from Buffalo to Defiance?

It takes approximately 8h 31m to get from Buffalo to Defiance, including transfers.

Can I drive from Buffalo to Defiance?

Yes, the driving distance between Buffalo to Defiance is 349 miles. It takes approximately 5h 58m to drive from Buffalo to Defiance.

Where can I stay near Defiance?

There are 12+ hotels available in Defiance.

Buffalo to Defiance - 4 ways to travel via train, bus, car, and plane

There are 4 ways to get from Buffalo to Defiance by train (Amtrak), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train (Amtrak)
best
1. Take the train from Buffalo Depew Station to Bryan Amtrak StationLake Shore Limited
8h 31m
$99–273
Drive 346.6 mi
cheapest
1. Drive from Buffalo to Defiance346.6 mi
5h 58m
$64–92
Bus, train
1. Take the bus from Buffalo to Cleveland Bus Station
2. Take the bus from Cleveland Bus Station to Toledo Bus Stop
3. Take the train from Toledo to Bryan Amtrak Station
8h 50m
$98–218
Fly, bus, train
1. Fly from Buffalo Niagara International Airport (BUF) to Detroit (DTW)BUF - DTW
2. Take the bus from Dearborn to Toledo
3. Take the train from Toledo to Bryan Amtrak Station
8h 33m

Buffalo Niagara International Airport (BUF) to Detroit (DTW) flights

28Weekly Planes

1h 20mAverage Duration

$67Cheapest Price

See schedules

Questions & Answers

Launch map view

Distance: 373.9 mi
Duration: 8h 31m

What companies run services between Buffalo, NY, USA and Defiance, OH, USA?

Amtrak operates a train from Buffalo Depew Station to Bryan Amtrak Station twice daily. Tickets cost $35–130 and the journey takes 6h 44m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines

Train operators

Bus operators

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