There are 5 ways to get from Minneapolis to Defiance by plane, taxi, bus (Greyhound, Flixbus, Amtrak), train (Amtrak), car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA)plane MSP - FWA
- Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi
4h 5m$212–572Drive 604.8 mi
cheapest- Drive from Minneapolis to Defiancecar 604.8 mi
11h$111–160Bus
- Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus Greyhound US0150 / ...
- Take the bus from Chicago Union Station to Bryan Amtrak Stationbus Amtrak Thruway Connecting Service
13h 22m$183–284Train (Amtrak)
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain Borealis / ...
- Take the train from Chicago Union Station to Bryan Amtrak Stationtrain Lake Shore Limited
13h 37m$242–462Bus via Madison
- Take the bus from UMN - Minneapolis to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Union Station to Bryan Amtrak Stationbus
15h 41m$221–328
Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA) flights
Questions & Answers
The cheapest way to get from Minneapolis to Defiance is to drive which costs $110 - $160 and takes 11h.
The fastest way to get from Minneapolis to Defiance is to fly and taxi which takes 4h 5m and costs $210 - $600.
No, there is no direct bus from Minneapolis station to Defiance station. However, there are services departing from Minneapolis Bus Station and arriving at Bryan Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 13h 22m.
No, there is no direct train from Minneapolis to Defiance station. However, there are services departing from St. Paul-Minneapolis and arriving at Bryan Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 13h 37m.
The distance between Minneapolis and Defiance is 550 miles. The road distance is 608.3 miles.
The best way to get from Minneapolis to Defiance without a car is to bus which takes 13h 22m and costs $180 - $290.
It takes approximately 4h 5m to get from Minneapolis to Defiance, including transfers.
Minneapolis to Defiance bus services, operated by Greyhound USA, depart from Minneapolis Bus Station.
Minneapolis to Defiance train services, operated by Amtrak, depart from St. Paul-Minneapolis station.
The best way to get from Minneapolis to Defiance is to bus which takes 13h 22m and costs $180 - $290. Alternatively, you can train, which costs $240 - $470 and takes 13h 37m.
What companies run services between Minneapolis, MN, USA and Defiance, OH, USA?
You can take a bus from Minneapolis Bus Station to Defiance via Chicago Bus Station, Chicago Union Station, and Bryan Amtrak Station in around 13h 22m. Alternatively, you can take a bus from 6th St S & 5th Ave S to Defiance via Union Depot Station & Terminal, St. Paul-Minneapolis, Chicago Union Station, and Bryan Amtrak Station in around 13h 37m.
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $70–390
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport via Detroit
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $80–430
- Website
- united.com
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $70–400
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Minneapolis Bus Station to Chicago Bus Station
- Ave. Duration
- 8h 30m
- Frequency
- 4 times a day
- Estimated price
- $65–120
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Minneapolis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Once a week
- Estimated price
- $65–95
- Website
- https://www.amtrak.com/home.html
Bus from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Once a week
- Estimated price
- $65–95
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from UMN - Minneapolis to Madison
- Ave. Duration
- 6h 10m
- Frequency
- 5 times a week
- Estimated price
- $75–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $75–110
- Phone
- +1 (866) 912 - 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- coachusa.com
- Adult
- $26–60
- Ave. Duration
- 1h 5m
- Estimated price
- $140–180
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Minneapolis to Defiance bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Defiance is 1h ahead of Minneapolis. It is currently 9:38 PM in Minneapolis and 10:38 PM in Defiance.
Minneapolis to Defiance train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Minneapolis to Defiance is 608 miles. It takes approximately 11h to drive from Minneapolis to Defiance.
There are 10+ hotels available in Defiance.











