Rome2Rio

How to get fromMinneapolis to Defianceby plane, taxi, bus (Greyhound, Flixbus, Amtrak), train (Amtrak), car, or bus (Amtrak)

Find Transport to Defiance

See all options

There are 5 ways to get from Minneapolis to Defiance by plane, taxi, bus (Greyhound, Flixbus, Amtrak), train (Amtrak), car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, taxi

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA)plane plane MSP - FWA
    2. Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi taxi
    4h 5m
    $207–582

  2. Drive 604.8 mi

    cheapest
    1. Drive from Minneapolis to Defiancecar car 604.8 mi
    11h
    $111–160

  3. Bus

    1. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus Greyhound US0150 / ...
    2. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    13h 22m
    $171–293

  4. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train Borealis / ...
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    13h 37m
    $227–452

  5. Bus via Madison

    1. Take the bus from U of MN Campus to Madison, WI-Lake St.bus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus
    14h 16m
    $198–299

Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA) flights

Calendar35Weekly Planes
Duration3h 35mAverage Duration
Ticket$67Cheapest Price
See schedules

Questions & Answers

What companies run services between Minneapolis, MN, USA and Defiance, OH, USA?

You can take a bus from Minneapolis Bus Station to Defiance via Chicago Bus Station, Chicago Union Station, and Bryan Amtrak Station in around 13h 22m. Alternatively, you can take a bus from 6th St S & 5th Ave S to Defiance via Union Depot Station & Terminal, St. Paul-Minneapolis, Chicago Union Station, and Bryan Amtrak Station in around 13h 37m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Minneapolis

Trips to Defiance

Popular routes