The average train between Wertheim and Mainz takes 3h 5m and the fastest train takes 2h 48m. There is a train service every few hours from Wertheim to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Wertheim and Mainz. The earliest departure is at 5:00 AM in the morning, and the last departure from Wertheim is at 9:35 PM which arrives into Mainz at 12:52 AM. All services require a transfer at Aschaffenburg Hbf and take an average of 3h 5m. The schedules shown below are for the next available departures.


3h 22m • 2 changes


2h 48m • 2 changes


3h 22m • 2 changes


2h 55m • 2 changes


3h 22m • 2 changes


2h 48m • 2 changes


3h 22m • 2 changes


2h 55m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes


2h 56m • 2 changes
Want to know about travelling from Wertheim to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wertheim to Mainz. However, there are services departing from Wertheim station and arriving at Mainz station via Aschaffenburg Hbf. The journey, including transfers, takes approximately 3h 5m.
Wertheim to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), depart from Wertheim, Bahnhof station.
Wertheim to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mainz, Römisches Theater station.
The distance between Wertheim and Mainz is 91.6 km. The road distance is 150 km.
You can take a train from Wertheim, Bahnhof to Mainz, Römisches Theater via Aschaffenburg Hbf and Frankfurt in around 3h 8m.