The average train between Naples and Mainz takes 16h 39m and the fastest train takes 13h 16m. The train service runs several times per day from Naples to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Naples and Mainz. The earliest departure is at 6:02 AM in the morning, and the last departure from Naples is at 6:35 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Milano Centrale and take an average of 16h 39m. The schedules shown below are for the next available departures.



13h 16m • 3 changes



14h 33m • 3 changes
Arrives next day



20h 33m • 3 changes
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20h 43m • 3 changes



13h 16m • 3 changes



14h 33m • 3 changes
Arrives next day



21h 33m • 3 changes
Arrives next day



20h 43m • 3 changes



13h 16m • 3 changes



14h 33m • 3 changes
Arrives next day



18h 3m • 3 changes
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20h 43m • 3 changes



13h 16m • 3 changes



14h 33m • 3 changes
Arrives next day



18h 3m • 3 changes
Arrives next day



20h 43m • 3 changes
Want to know about travelling from Naples to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Naples to Mainz. However, there are services departing from Naples station and arriving at Mainz station via Milano Centrale. The journey, including transfers, takes approximately 16h 39m.
Naples to Mainz train services, operated by ItaloTreno, depart from Napoli station.
Naples to Mainz train services, operated by ItaloTreno, arrive at Mainz, Hauptbahnhof station.
Book your Naples to Mainz train tickets online with ItaloTreno, Trenitalia EuroCity and 2 other operators.
The distance between Naples and Mainz is 1,117 km. The road distance is 1,469 km.
You can take a train from Napoli to Mainz, Hauptbahnhof via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 13h 19m.