The average train between Italy and Mainz takes 14h 53m and the fastest train takes 11h 48m. The train service runs several times per day from Italy to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Italy and Mainz. The earliest departure is at 6:30 AM in the morning, and the last departure from Italy is at 8:05 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Milano Centrale and take an average of 14h 53m. The schedules shown below are for the next available departures.



11h 48m • 3 changes
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16h 42m • 3 changes
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15h 28m • 3 changes
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19h 13m • 3 changes



11h 48m • 3 changes
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16h 42m • 3 changes
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15h 28m • 3 changes
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19h 13m • 3 changes



12h 8m • 3 changes



12h 48m • 3 changes
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18h 33m • 3 changes
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19h 13m • 3 changes



12h 13m • 3 changes



11h 48m • 3 changes



12h 48m • 3 changes
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17h 58m • 3 changes



12h 13m • 3 changes



11h 48m • 3 changes



12h 48m • 3 changes
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18h 23m • 3 changes



12h 13m • 3 changes



11h 48m • 3 changes



12h 48m • 3 changes
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15h 28m • 3 changes
Want to know about travelling from Italy to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Italy to Mainz. However, there are services departing from Italy station and arriving at Mainz station via Milano Centrale. The journey, including transfers, takes approximately 14h 53m.
Italy to Mainz train services, operated by ItaloTreno, depart from Roma Termini station.
Italy to Mainz train services, operated by ItaloTreno, arrive at Mainz, Hauptbahnhof station.
Book your Italy to Mainz train tickets online with ItaloTreno, Trenitalia EuroCity and 3 other operators.
The distance between Italy and Mainz is 883.4 km. The road distance is 1,266 km.
You can take a train from Roma Termini to Mainz, Hauptbahnhof via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 11h 43m.