The average train between Wertheim and Cologne takes 4h 15m and the fastest train takes 3h 18m. The train service runs several times per day from Wertheim to Cologne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Wertheim and Cologne. The earliest departure is at 5:56 AM in the morning, and the last departure from Wertheim is at 9:35 PM which arrives into Cologne at 10:14 AM. All services require a transfer, and take on average 4h 15m. The schedules shown below are for the next available departures.

3h 18m • 1 change

4h 14m • 1 change

3h 47m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 18m • 1 change

4h 14m • 1 change

3h 47m • 1 change

3h 48m • 1 change
Want to know about travelling from Wertheim to Cologne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wertheim to Cologne. However, there are services departing from Wertheim station and arriving at Cologne station via Aschaffenburg Hbf. The journey, including transfers, takes approximately 4h 15m.
Wertheim to Cologne train services, operated by Deutsche Bahn Regio (DB Regional), depart from Wertheim, Bahnhof station.
Wertheim to Cologne train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Köln Messe/Deutz Bf station.
Book your Wertheim to Cologne train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Wertheim and Cologne is 223.6 km. The road distance is 291 km.
You can take a train from Wertheim, Bahnhof to Köln Messe/Deutz Bf via Aschaffenburg Hbf in around 3h 55m.