Florence to Mainz Trains

Trip Overview

The average train between Florence and Mainz takes 14h 1m and the fastest train takes 10h 53m. The train service runs several times per day from Florence to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 1m
Duration: 989 km
Distance: €233
Average price: 5 times a day
Frequency

Train via Basel

best

Take the train from Firenze Santa Maria Novella to Milano Centraletrain
Take the train from Milano Centrale to Basel Sbbtrain Ec
Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain S5 / ...

11h 27m

€164–354

Florence to Mainz train times

Trains run 5 times a day between Florence and Mainz. The earliest departure is at 7:25 AM in the morning, and the last departure from Florence is at 6:25 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Milano Centrale and take an average of 14h 1m. The schedules shown below are for the next available departures.

Departing Tuesday, October 27, 2026

7:25 AM → 6:43 PM
11h 18m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 11:53 PM
11h 28m • 3 changes
3:25 PM → 6:08 AM
Arrives next day
14h 43m • 3 changes
Show more

Departing Wednesday, October 28, 2026

7:25 AM → 6:43 PM
11h 18m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 3:47 AM
Arrives next day
15h 22m • 3 changes
3:25 PM → 5:38 AM
Arrives next day
14h 13m • 3 changes
Show more

Departing Thursday, October 29, 2026

7:25 AM → 6:43 PM
11h 18m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 11:53 PM
11h 28m • 3 changes
3:25 PM → 5:38 AM
Arrives next day
14h 13m • 3 changes
Show more

Departing Friday, October 30, 2026

7:25 AM → 6:43 PM
11h 18m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 3:47 AM
Arrives next day
15h 22m • 3 changes
3:25 PM → 8:43 AM
Arrives next day
17h 18m • 3 changes
Show more

Departing Saturday, October 31, 2026

7:25 AM → 6:36 PM
11h 11m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 11:53 PM
11h 28m • 3 changes
3:25 PM → 8:08 AM
Arrives next day
16h 43m • 3 changes
Show more

Departing Sunday, November 1, 2026

7:25 AM → 6:43 PM
11h 18m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 11:53 PM
11h 28m • 3 changes
3:25 PM → 8:33 AM
Arrives next day
17h 8m • 3 changes
Show more

Departing Monday, November 2, 2026

7:25 AM → 6:43 PM
11h 18m • 3 changes
8:25 AM → 7:18 PM
10h 53m • 3 changes
12:25 PM → 11:53 PM
11h 28m • 3 changes

Frequently asked questions

Want to know about travelling from Florence to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Florence, Italy and Mainz, Germany?

You can take a train from Firenze Santa Maria Novella to Mainz, Hauptbahnhof via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 11h 27m.

Operators