The average train between Antwerp and Mainz takes 4h 21m and the fastest train takes 3h 50m. The train service runs several times per day from Antwerp to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Antwerp and Mainz. The earliest departure is at 5:05 AM in the morning, and the last departure from Antwerp is at 7:54 PM which arrives into Mainz at 1:22 AM. All services require a transfer at Brussels-Nord and take an average of 4h 21m. The schedules shown below are for the next available departures.


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4h 39m • 2 changes


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3h 50m • 2 changes


4h 39m • 2 changes


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3h 50m • 2 changes
Want to know about travelling from Antwerp to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Antwerp to Mainz. However, there are services departing from Antwerp station and arriving at Mainz station via Brussels-Nord. The journey, including transfers, takes approximately 4h 21m.
Antwerp to Mainz train services, operated by Belgian Railways (NMBS/SNCB), depart from Anvers-Central station.
Antwerp to Mainz train services, operated by Belgian Railways (NMBS/SNCB), arrive at Frankfurt(M) Flughafen Fernbf station.
Book your Antwerp to Mainz train tickets online with Belgian Railways (NMBS/SNCB), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Antwerp and Mainz is 306.3 km. The road distance is 455 km.
You can take a train from Anvers-Central to Mainz, Römisches Theater via Brussels-Nord, Frankfurt(M) Flughafen Fernbf, and Frankfurt in around 4h 37m.