Prague to Mainz Trains

Prague to Mainz trains

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Trip Overview

The average train between Prague and Mainz takes 9h 26m and the fastest train takes 8h 9m. The train service runs several times per day from Prague to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 26m
Duration: 603 km
Distance: €141
Average price: Every 4 hours
Frequency

Train via Nuremberg

best

Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
Take the train from Schwandorf to Nürnberg Hbftrain
Take the train from Nürnberg Hbf to Frankfurttrain 41 / ...

9h 5m

€113–255

Prague to Mainz train times

Trains run every 4 hours between Prague and Mainz. The earliest departure is at 5:35 AM in the morning, and the last departure from Prague is at 5:35 PM which arrives into Mainz at 8:22 AM. All services require a transfer at Schwandorf and take an average of 9h 26m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

3:35 PM → 6:23 AM
Arrives next day
14h 48m • 3 changes
5:35 PM → 8:23 AM
Arrives next day
14h 48m • 3 changes

Departing Sunday, October 11, 2026

5:35 AM → 1:44 PM
8h 9m • 3 changes
7:35 AM → 3:44 PM
8h 9m • 3 changes
9:35 AM → 5:44 PM
8h 9m • 3 changes
11:35 AM → 8:23 PM
8h 48m • 3 changes
Show more

Departing Monday, October 12, 2026

5:35 AM → 1:44 PM
8h 9m • 3 changes
7:35 AM → 3:44 PM
8h 9m • 3 changes
9:35 AM → 5:44 PM
8h 9m • 3 changes
11:35 AM → 8:22 PM
8h 47m • 3 changes
Show more

Departing Tuesday, October 13, 2026

5:35 AM → 1:44 PM
8h 9m • 3 changes
7:35 AM → 3:44 PM
8h 9m • 3 changes
9:35 AM → 5:44 PM
8h 9m • 3 changes
11:35 AM → 8:22 PM
8h 47m • 3 changes
Show more

Departing Wednesday, October 14, 2026

5:35 AM → 1:44 PM
8h 9m • 3 changes
7:35 AM → 3:44 PM
8h 9m • 3 changes
9:35 AM → 5:44 PM
8h 9m • 3 changes
11:35 AM → 8:22 PM
8h 47m • 3 changes
Show more

Departing Thursday, October 15, 2026

5:35 AM → 1:44 PM
8h 9m • 3 changes
7:35 AM → 3:44 PM
8h 9m • 3 changes
9:35 AM → 5:44 PM
8h 9m • 3 changes
11:35 AM → 8:22 PM
8h 47m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Prague to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Train via Nuremberg

Prague to Mainz train times

Departing Saturday, October 10, 2026

3:35 PM → 6:23 AM
Arrives next day

5:35 PM → 8:23 AM
Arrives next day

Departing Sunday, October 11, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:23 PM

Departing Monday, October 12, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Departing Tuesday, October 13, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Departing Wednesday, October 14, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Departing Thursday, October 15, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Frequently asked questions

What companies run services between Prague, Czechia and Mainz, Germany?

Train from Praha Hlavni Nadrazi to Schwandorf

Prague to Mainz trains

Find Transport to Mainz

Trip Overview

Train via Nuremberg

Prague to Mainz train times

Departing Saturday, October 10, 2026

3:35 PM → 6:23 AMArrives next day

5:35 PM → 8:23 AMArrives next day

Departing Sunday, October 11, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:23 PM

Departing Monday, October 12, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Departing Tuesday, October 13, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Departing Wednesday, October 14, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Departing Thursday, October 15, 2026

5:35 AM → 1:44 PM

7:35 AM → 3:44 PM

9:35 AM → 5:44 PM

11:35 AM → 8:22 PM

Frequently asked questions

What companies run services between Prague, Czechia and Mainz, Germany?

Train from Praha Hlavni Nadrazi to Schwandorf

Train trips from Prague

Train trips to Mainz

Alternative transport options

3:35 PM → 6:23 AM
Arrives next day

5:35 PM → 8:23 AM
Arrives next day