There are 7 ways to get from Prague to Mainz by train, bus, car, subway or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6 h 49 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Frankfurt(Main)Hbf Ice / ...

$108 - $159

Cheapest option

Bus RegioJet  •  8 h 14 min

  1. Take the bus from Praha, ÚAN Florenc to Frankfurt nad Mohanem, Hbf. Südseite, Pforzheimer Straße Rj / ...

$20 - $52

5 alternative options

Bus Eurolines CZ  •  8 h 34 min

  1. Take the bus from Praha ÚAN Florenc to Frankfurt

$27 - $45

Drive  •  4 h 57 min

  1. Drive from Prague to Mainz 338 miles

$70 - $110

Subway to Prague, fly to Frankfurt  •  4 h 30 min

  1. Take the subway from Staroměstská to Nádraží Veleslavín
  2. Fly from Prague (PRG) to Frankfurt (FRA) PRG - FRA

$70 - $241

Bus to Dresden, fly to Frankfurt  •  5 h 22 min

  1. Take the bus from Praha, ÚAN Florenc to Drážďany, Letiště
  2. Fly from Dresden (DRS) to Frankfurt (FRA) DRS - FRA

$84 - $276

Fly Prague to Luxembourg, bus  •  7 h 13 min

  1. Fly from Prague (PRG) to Luxembourg (LUX) PRG - LUX
  2. Take the bus from Luxembourg to Mainz

$96 - $446

Questions & Answers

The cheapest way to get from Prague to Mainz is to bus which costs 430 Kč - 1 200 Kč and takes 8 h 14 min.

More details

The quickest way to get from Prague to Mainz is to subway and fly which costs 1 500 Kč - 5 500 Kč and takes 4 h 30 min.

More details

The distance between Prague and Mainz is 439 km. The road distance is 540.9 km.

Get driving directions

It takes approximately 6 h 49 min to get from Prague to Mainz, including transfers.

More details

No, there is no direct bus from Prague to Mainz. However, there are services departing from Praha, ÚAN Florenc and arriving at Mainz via Frankfurt. The journey, including transfers, takes approximately 8 h 14 min.

More details

No, there is no direct train from Prague to Mainz. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Mainz-Kastel via Nürnberg Hbf and Frankfurt(Main)Hbf. The journey, including transfers, takes approximately 6 h 49 min.

More details

What companies run services between Prague, Czech Republic and Mainz, Germany?

You can take a train from Prague to Mainz via Nürnberg ZOB, Nürnberg Hbf, and Frankfurt(Main)Hbf in around 6 h 49 min. Alternatively, RegioJet operates a bus from Prague to Mainz 3 times a day. Tickets cost $17 - $22 and the journey takes 6 h 55 min. FlixBus also services this route 3 times a day.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Frankfurt
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$100 - $480
Flights from Prague to Frankfurt via Munich
Ave. Duration
3 h
When
Every day
Estimated price
$100 - $480
Flights from Dresden to Frankfurt
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Munich
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Dusseldorf
Ave. Duration
2 h 50 min
When
Monday to Friday
Estimated price
$45 - $210
Flights from Prague to Luxembourg via Munich
Ave. Duration
3 h 23 min
When
Every day
Estimated price
$190 - $1,000
Luxair
Website
luxair.lu
Flights from Prague to Frankfurt
Ave. Duration
1 h 7 min
When
Every day
Estimated price
$100 - $480
Flights from Prague to Luxembourg
Ave. Duration
1 h 20 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$190 - $1,900
CSA
Website
csa.cz
Flights from Prague to Frankfurt
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$60 - $360
KLM
Website
klm.com
Flights from Prague to Luxembourg via Amsterdam
Ave. Duration
3 h 22 min
When
Every day
Estimated price
$170 - $600
Swiss
Website
swiss.com
Flights from Prague to Luxembourg via Zurich
Ave. Duration
3 h 35 min
When
Monday to Friday
Estimated price
$190 - $1,300
Train operators
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Prague Public Transit Co.
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Praha, ÚAN Florenc to Frankfurt nad Mohanem, Hbf. Südseite, Pforzheimer Straße
Ave. Duration
6 h 55 min
Frequency
3 times a day
Estimated price
$17 - $22
Schedules at
regiojet.sk
Bus from Praha, ÚAN Florenc to Drážďany, Letiště
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Schedules at
regiojet.sk
FlixBus
Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Prague, Prague ÚAN Florenc to Frankfurt, Frankfurt central station
Ave. Duration
6 h 35 min
Frequency
3 times a day
Estimated price
$29 - $50
Website
flixbus.co.uk
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Frankfurt
Ave. Duration
7 h 15 min
Frequency
Twice daily
Estimated price
$24 - $45
Schedules at
elines.cz
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Prague Florenc to Frankfurt Hbf
Ave. Duration
7 h 30 min
Frequency
5 times a week
Estimated price
$50 - $75
Website
eurolines.de
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Luxembourg to Mainz
Ave. Duration
2 h 25 min
Frequency
Hourly
Estimated price
$7 - $11
Website
Ouibus

Want to know more about travelling around Germany

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.