There are 7 ways to get from Prague to Mainz by subway, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Václav Havel Airport Prague, fly
best- Take the subway from Staroměstská to Nádraží Veleslavín
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)PRG - FRA
4h 2mBus
cheapest- Take the bus from Prague to Mainz central train stationN1310
8h 5m€30–80Bus via Frankfurt am Main
- Take the bus from Prague to Frankfurt central train stationN870
8h 4m€34–82Train via Dresden
- Take the train from Praha Hlavni Nadrazi to Dresden HbfEc
- Take the train from Dresden Hauptbahnhof to Mainz, Hauptbahnhof50
8h 26m€58–159Drive 539.5 km
- Drive from Prague to Mainz539.5 km
4h 41m€82–118Train to Dresden Airport, fly
- Take the train from Praha Hlavni Nadrazi to Dresden Hbf
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)DRS - FRA
5h 41m€142–302Train
- Take the train from Praha Hlavni Nadrazi to Frankfurt(Main)SuedEc
10h 5m€124–182
Prague to Mainz by bus, foot, and train
Questions & Answers
The cheapest way to get from Prague to Mainz is to bus which costs €30 - €80 and takes 8h 5m.
The fastest way to get from Prague to Mainz is to drive which takes 4h 41m and costs €80 - €120.
Yes, there is a direct bus departing from Prague and arriving at Mainz central train station station. Services depart once daily, and operate every day. The journey takes approximately 8h 5m.
No, there is no direct train from Prague to Mainz. However, there are services departing from Praha Hlavni Nadrazi and arriving at Mainz, Hauptbahnhof via Dresden Hauptbahnhof. The journey, including transfers, takes approximately 8h 26m.
The distance between Prague and Mainz is 447 km. The road distance is 539.5 km.
The best way to get from Prague to Mainz without a car is to bus via Frankfurt am Main which takes 8h 4m and costs €30 - €85.
It takes approximately 4h 2m to get from Prague to Mainz, including transfers.
Prague to Mainz bus services, operated by FlixBus, depart from Prague station.
Prague to Mainz train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Mainz is to bus via Frankfurt am Main which takes 8h 4m and costs €30 - €85. Alternatively, you can train via Dresden, which costs €55 - €160 and takes 8h 26m.
What companies run services between Prague, Czechia and Mainz, Germany?
FlixBus operates a bus from Prague to Frankfurt central train station 5 times a day. Tickets cost €26–70 and the journey takes 7h 10m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mainz, Hauptbahnhof via Dresden Hauptbahnhof in around 8h 26m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €80–280
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €80–170
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–290
Flights from Dresden Airport to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €120–290
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €60–140
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €85–280
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid.cz
Subway from Staroměstská to Nádraží Veleslavín
- Ave. Duration
- 9 min
- Frequency
- Every 10 minutes
- Website
- https://pid.cz/en/
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 22m
- Frequency
- 5 times a day
- Estimated price
- €35–55
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Frankfurt(Main)Sued
- Ave. Duration
- 9h 4m
- Frequency
- 5 times a week
- Estimated price
- €110–150
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 19m
- Frequency
- 5 times a day
- Estimated price
- €11–24
- Website
- https://www.cd.cz/en/default.htm
- 2nd Class
- €11–16
- 1st Class
- €18–24
- Business
- €19–21
- Phone
- +36 (1) 3 49 49 49
- info@mavcsoport.hu
- Website
- jegy.mav.hu
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Once daily
- Estimated price
- €8–10
- Website
- https://jegy.mav.hu/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Dresden Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 5h 4m
- Frequency
- Every 4 hours
- Estimated price
- €50–150
- Website
- https://int.bahn.de/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Prague to Frankfurt central train station
- Ave. Duration
- 7h 10m
- Frequency
- 5 times a day
- Estimated price
- €26–70
- Website
- https://www.flixbus.co.uk
Bus from Prague to Mainz central train station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- €30–80
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
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More Questions & Answers
Prague to Mainz bus services, operated by FlixBus, arrive at Mainz central train station.
Prague to Mainz train services, operated by ÖBB EuroCity, arrive at Dresden Hbf station.
Yes, the driving distance between Prague to Mainz is 540 km. It takes approximately 4h 41m to drive from Prague to Mainz.
Book your Prague to Mainz train tickets online with Omio.
Book your Prague to Mainz bus tickets online with Omio and FlixBus.
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