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How to get fromPrague to Mainzby subway, plane, bus, train or car

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There are 9 ways to get from Prague to Mainz by subway, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Václav Havel Airport Prague, fly

    best
    1. Take the subway from Staroměstská to Nádraží Veleslavínsubway subway
    2. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    4h 5m
    €74–167

  2. Bus

    cheapest
    1. Take the bus from Prague to Mainz central train stationbus bus N1310
    8h 5m
    €29–50

  3. Bus via Frankfurt am Main

    1. Take the bus from Praha, ÚAN Florenc to Frankfurt Central Train Stationbus bus RegioJet 540
    8h 1m
    €31–48

  4. Train via Dresden

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train Rj
    2. Take the train from Dresden Hauptbahnhof to Frankfurttrain train 50
    8h 24m
    €57–145

  5. Drive 539.5 km

    1. Drive from Prague to Mainzcar car 539.5 km
    4h 31m
    €81–118

  6. Train to Dresden Airport, fly

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    5h 31m
    €155–343

  7. Bus to Nuremberg Airport, fly

    1. Take the bus from Prague to Nuremberg central bus stationbus bus
    2. Fly from Nuremberg Airport (NUE) to Frankfurt (FRA)plane plane NUE - FRA
    6h
    €108–221

  8. Train

    1. Take the train from Praha Hlavni Nadrazi to Frankfurt(Main)Suedtrain train Ec
    10h 25m
    €123–160

  9. Bus via Mainz, Römisches Theater

    1. Take the bus from Praha Hlavní nádraží to Frankfurt, Hauptbahnhof FOBbus bus Ivano-Frankivsk
    17h 51m

Prague to Mainz by bus

Calendar7Weekly Buses
Duration8h 1mAverage Duration
Ticket€31Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Mainz, Germany?

RegioJet operates a bus from Praha, ÚAN Florenc to Frankfurt Central Train Station once daily. Tickets cost €25–40 and the journey takes 6h 25m. Alternatively, you can take a train from Praha-Holesovice to Mainz, Römisches Theater via Dresden Hauptbahnhof and Frankfurt in around 8h 24m.

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