There are 8 ways to get from Prague to Mainz by train, bus, night train, car, subway or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  7 h 3 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Frankfurt(Main)Hbf Ice / ...

$103 - $153

Cheapest option

Bus Arriva Stredni Cechy  •  8 h 7 min

  1. Take the bus from Praha hl. n. to Frankfurt Flughafen T1 43491

$40 - $51

6 alternative options

Bus Eurolines CZ  •  13 h 24 min

  1. Take the bus from Praha ÚAN Florenc to Frankfurt

$63 - $91

Night train  •  8 h 45 min

  1. Take the night train from Praha hl.n. (Autobusová St. Wilsonova) to Frankfurt(M)Hbf Stuttgarter Str.

$107 - $153

Drive  •  4 h 57 min

  1. Drive from Prague to Mainz 338 miles

$70 - $110

Subway to Prague, fly  •  4 h 18 min

  1. Take the subway from Staroměstská to Nádraží Veleslavín
  2. Fly from Prague (PRG) to Frankfurt (FRA) PRG - FRA

$70 - $242

Bus to Dresden, fly  •  5 h 12 min

  1. Take the bus from Prague, ÚAN Florenc to Dresden, Letiště
  2. Fly from Dresden (DRS) to Frankfurt (FRA) DRS - FRA

$84 - $277

Train to Nuremberg, fly  •  6 h 26 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Fly from Nuremberg (NUE) to Frankfurt (FRA) NUE - FRA

$133 - $263

Questions & Answers

No, there is no direct train from Prague to Mainz. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Mainz Hbf via Nürnberg Hbf and Frankfurt(Main)Hbf. The journey, including transfers, takes approximately 7 h 3 min.

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The distance between Prague and Mainz is 439 km. The road distance is 540.9 km.

Get driving directions

The best way to get from Prague to Mainz without a car is to train which takes 7 h 3 min and costs .

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It takes approximately 7 h 3 min to get from Prague to Mainz, including transfers.

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Prague to Mainz train services, operated by Czech Railways (ČD), depart from Praha hl.n. (Autobusová St. Wilsonova) station.

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The best way to get from Prague to Mainz is to train which takes 7 h 3 min and costs . Alternatively, you can bus, which costs and takes 8 h 7 min.

Mode details

The quickest flight from Prague Airport to Frankfurt Airport is the direct flight which takes 1 h 5 min.

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Prague to Mainz train services, operated by Deutsche Bahn, arrive at Frankfurt(Main)Hbf station.

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Yes, the driving distance between Prague to Mainz is 541 km. It takes approximately 4 h 57 min to drive from Prague to Mainz.

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CSA and Lufthansa offer flights from Prague Airport to Frankfurt Airport.

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Map of how to get from Prague to Mainz.
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  • Distance: 274.2 miles
  • Duration: 7 h 3 min

What companies run services between Prague, Czech Republic and Mainz, Germany?

You can take a train from Prague to Mainz via Nürnberg ZOB, Nürnberg Hbf, and Frankfurt(Main)Hbf in around 7 h 3 min. Alternatively, Arriva Stredni Cechy operates a bus from Prague to Mainz once daily. Tickets cost $27 - $32 and the journey takes 7 h 10 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Frankfurt
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$100 - $480
Flights from Prague to Frankfurt via Munich
Ave. Duration
3 h
When
Every day
Estimated price
$100 - $480
Flights from Dresden to Frankfurt
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Munich
Ave. Duration
2 h 56 min
When
Every day
Estimated price
$85 - $290
Flights from Nuremberg to Frankfurt
Ave. Duration
45 min
When
Every day
Estimated price
$85 - $300
CSA
Website
csa.cz
Flights from Prague to Frankfurt
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$60 - $360
Train operators
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Night train from Praha hl.n. (Autobusová St. Wilsonova) to Frankfurt(M)Hbf Stuttgarter Str.
Ave. Duration
7 h 35 min
Frequency
Once daily
Estimated price
$90 - $130
Website
cd.cz
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Nürnberg Hbf to Frankfurt(Main)Hbf
Ave. Duration
2 h 4 min
Frequency
Hourly
Estimated price
$45 - $70
Website
bahn.de
Prague Public Transit Co.
Bus operators
Arriva Stredni Cechy
Website
arriva-strednicechy.cz
Bus from Praha hl. n. to Frankfurt Flughafen T1
Ave. Duration
7 h 10 min
Frequency
Once daily
Estimated price
$27 - $32
Schedules at
arriva.cz
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Frankfurt
Ave. Duration
12 h 20 min
Frequency
3 times a day
Estimated price
$45 - $70
Schedules at
elines.cz
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Prague Florenc to Frankfurt Hbf
Ave. Duration
7 h 30 min
Frequency
5 times a week
Estimated price
$60 - $95
Website
eurolines.de
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Prague, ÚAN Florenc to Dresden, Letiště
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Website
regiojet.com

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There are 410+ hotels available in Mainz. Prices start at $58 USD per night.

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