The average train between Berlin and Mainz takes 6h 17m and the fastest train takes 5h 25m. There is a train service every few hours from Berlin to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Berlin and Mainz. The earliest departure is at 5:27 AM in the morning, and the last departure from Berlin is at 11:32 PM which arrives into Mainz at 6:22 AM. All services require a transfer, and take on average 6h 17m. The schedules shown below are for the next available departures.

6h 23m • 1 change

6h 26m • 1 change
Arrives next day

6h 16m • 1 change
Arrives next day

6h 25m • 1 change

6h 17m • 1 change

6h 13m • 1 change

6h 17m • 1 change

6h 13m • 1 change

6h 17m • 1 change

6h 13m • 1 change

6h 17m • 1 change

6h 13m • 1 change

6h 17m • 1 change

6h 13m • 1 change

6h 17m • 1 change

6h 13m • 1 change
Want to know about travelling from Berlin to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Berlin to Mainz. However, there are services departing from Berlin station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 6h 17m.
Berlin to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Berlin Hbf station.
Berlin to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Berlin to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and 2 other operators.
The distance between Berlin and Mainz is 455.1 km. The road distance is 549 km.
Deutsche Bahn Intercity (DB IC) operates a train from Berlin Hbf to Frankfurt hourly. Tickets cost €95–350 and the journey takes 4h 1m.