The average train between Berlin and Mainz takes 4h 56m and the fastest train takes 4h 38m. There is a train service every few hours from Berlin to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Berlin and Mainz. The earliest departure is at 4:28 AM at night, and the last departure from Berlin is at 9:27 PM which arrives into Mainz at 2:52 AM. All services require a transfer, and take on average 4h 56m. The schedules shown below are for the next available departures.

4h 44m • 1 change

4h 39m • 1 change

5h 2m • 1 change

5h 20m • 1 change

5h 16m • 1 change

5h 17m • 1 change

4h 38m • 1 change

4h 44m • 1 change

5h 16m • 1 change

5h 17m • 1 change

4h 38m • 1 change

4h 44m • 1 change
Want to know about travelling from Berlin to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Berlin to Mainz. However, there are services departing from Berlin station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 4h 56m.
Berlin to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Berlin Hbf station.
Berlin to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
The distance between Berlin and Mainz is 455.1 km. The road distance is 606 km.
Deutsche Bahn Intercity (DB IC) operates a train from Berlin Hbf to Frankfurt hourly. Tickets cost €110–250 and the journey takes 4h 13m.