Mainz to Pisa trains

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Trip Overview

The average train between Mainz and Pisa takes 15h 19m and the fastest train takes 11h 42m. The train service runs several times per day from Mainz to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 19m
Duration: 1,034 km
Distance: €251
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Pisa Centraletrain Re

13h

€122–431

Mainz to Pisa train times

Trains run every 4 hours between Mainz and Pisa. The earliest departure is at 1:43 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Pisa at 3:28 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 15h 19m. The schedules shown below are for the next available departures.

Departing Tuesday, October 27, 2026

7:46 AM → 7:28 PM
11h 42m • 5 changes
9:13 AM → 9:28 PM
12h 15m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes
1:13 PM → 8:28 AM
Arrives next day
19h 15m • 5 changes
Show more

Departing Wednesday, October 28, 2026

1:43 AM → 5:28 PM
15h 45m • 5 changes
7:46 AM → 7:28 PM
11h 42m • 5 changes
9:13 AM → 9:28 PM
12h 15m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes
Show more

Departing Thursday, October 29, 2026

1:43 AM → 5:28 PM
15h 45m • 5 changes
7:46 AM → 7:28 PM
11h 42m • 5 changes
9:13 AM → 9:28 PM
12h 15m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes
Show more

Departing Friday, October 30, 2026

2:01 AM → 5:28 PM
15h 27m • 5 changes
7:46 AM → 7:28 PM
11h 42m • 5 changes
9:13 AM → 9:28 PM
12h 15m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes
Show more

Departing Saturday, October 31, 2026

5:40 AM → 5:28 PM
11h 48m • 5 changes
9:13 AM → 9:28 PM
12h 15m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes
1:13 PM → 8:28 AM
Arrives next day
19h 15m • 5 changes
Show more

Departing Sunday, November 1, 2026

5:40 AM → 6:04 PM
12h 24m • 5 changes
9:13 AM → 9:59 PM
12h 46m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes
1:13 PM → 8:28 AM
Arrives next day
19h 15m • 5 changes
Show more

Departing Monday, November 2, 2026

5:40 AM → 5:28 PM
11h 48m • 5 changes
7:46 AM → 7:28 PM
11h 42m • 5 changes
9:13 AM → 9:28 PM
12h 15m • 5 changes
11:17 AM → 12:29 AM
Arrives next day
13h 12m • 5 changes

Frequently asked questions

Want to know about travelling from Mainz to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Launch map view

Distance: 1,034 km
Duration: 15h 19m

What companies run services between Mainz, Germany and Pisa, Italy?

You can take a train from Mainz, Hauptbahnhof to Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h.

Operators