The average bus between Mainz and Pisa takes 21h 53m and the fastest bus takes 21h 50m. There is at least one bus per day from Mainz to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Mainz and Pisa. The earliest departure is at 4:00 PM in the afternoon, and the last departure from Mainz is at 8:00 PM which arrives into Pisa at 6:05 PM. All services require a transfer at Frankfurt central train station and take an average of 21h 53m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Pisa. However, there are services departing from Mainz station and arriving at Pisa station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 21h 53m.
Mainz to Pisa bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Pisa bus services, operated by FlixBus, arrive at Pisa station.
Book your Mainz to Pisa bus tickets online with FlixBus.
The distance between Mainz and Pisa is 716.2 km. The road distance is 1,166 km.
You can take a bus from Mainz central train station to Pisa via Frankfurt central train station and Florence Villa Constanza Bus Station in around 20h 30m.