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How to get fromMainz to Pisaby plane, train, train (Trenitalia), bus or car

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There are 7 ways to get from Mainz to Pisa by plane, train, train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    5h 56m
    €118–308
  2. Bus

    cheapest
    1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus bus N77 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Pisabus bus N538 / ...
    20h 25m
    €58–136
  3. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train Ec
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Pisa Centraletrain train Re
    14h 3m
    €119–424
  4. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the bus from Mannheim Central Bus Station to Milanbus bus
    3. Take the bus from San Donato - Nuova Autostazione to P.Za D'Azegliobus bus
    20h 23m
    €74–160
  5. Drive 941.7 km

    1. Drive from Mainz to Pisacar car 941.7 km
    9h 5m
    €147–212
  6. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    6h 32m
    €137–340
  7. Train via Zurich

    1. Take the train from Mainz Hbf to Zürich HBtrain train
    2. Take the train from Zürich HB to Como S. Giovannitrain train Ec
    3. Take the train from Como S.Giovanni to Milano Porta Garibalditrain train S11
    4. Take the train from Milano P.Garibaldi to Pisa Centraletrain train Re
    17h 24m
    €187–437

Mainz to Pisa by train

Calendar84Weekly Trains
Duration14h 3mAverage Duration
Ticket€119Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Pisa, Italy?

You can take a train from Mainz, Römisches Theater to Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 14h 3m. Alternatively, you can take a bus from Mainz central train station to Pisa via Frankfurt central train station and Florence Villa Constanza Bus Station in around 20h 25m.

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