There are 7 ways to get from Mainz to Pisa by plane, train, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
5h 56m€118–308Bus
cheapest- Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus N77 / ...
- Take the bus from Florence Villa Constanza Bus Station to Pisabus N538 / ...
20h 25m€58–136Train
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain Ec
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Pisa Centraletrain Re
14h 3m€119–424Train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the bus from Mannheim Central Bus Station to Milanbus
- Take the bus from San Donato - Nuova Autostazione to P.Za D'Azegliobus
20h 23m€74–160Drive 941.7 km
- Drive from Mainz to Pisacar 941.7 km
9h 5m€147–212Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Pisa Centraletrain
6h 32m€137–340Train via Zurich
- Take the train from Mainz Hbf to Zürich HBtrain
- Take the train from Zürich HB to Como S. Giovannitrain Ec
- Take the train from Como S.Giovanni to Milano Porta Garibalditrain S11
- Take the train from Milano P.Garibaldi to Pisa Centraletrain Re
17h 24m€187–437
Mainz to Pisa by train
Questions & Answers
The cheapest way to get from Mainz to Pisa is to bus which costs €55 - €140 and takes 20h 25m.
The fastest way to get from Mainz to Pisa is to fly and train which takes 5h 56m and costs €110 - €310.
No, there is no direct bus from Mainz station to Pisa. However, there are services departing from Mainz central train station and arriving at Pisa via Frankfurt central train station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 20h 25m.
No, there is no direct train from Mainz to Pisa. However, there are services departing from Mainz, Römisches Theater and arriving at Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 14h 3m.
The distance between Mainz and Pisa is 832 km. The road distance is 941.7 km.
The best way to get from Mainz to Pisa without a car is to train which takes 14h 3m and costs €110 - €430.
It takes approximately 5h 56m to get from Mainz to Pisa, including transfers.
Mainz to Pisa bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Pisa train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
The best way to get from Mainz to Pisa is to train which takes 14h 3m and costs €110 - €430. Alternatively, you can bus, which costs €55 - €140 and takes 20h 25m.
What companies run services between Mainz, Germany and Pisa, Italy?
You can take a train from Mainz, Römisches Theater to Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 14h 3m. Alternatively, you can take a bus from Mainz central train station to Pisa via Frankfurt central train station and Florence Villa Constanza Bus Station in around 20h 25m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–250
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €110–250
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €90–320
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €100–320
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–250
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €95–320
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €90–350
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
Train from Milano P.Garibaldi to Pisa Centrale
- Ave. Duration
- 5h 7m
- Frequency
- Once daily
- Estimated price
- €25
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €30–80
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €40–140
- Website
- https://www.ns.nl/en
- 2nd Class
- €40–60
- 1st Class
- €80–140
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- €70–240
- Website
- https://www.ns.nl/en
- 2nd Class
- €70–110
- 1st Class
- €140–240
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 55m
- Frequency
- Every 2 hours
- Estimated price
- €55–110
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €23–45
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Como S. Giovanni
- Ave. Duration
- 2h 35m
- Frequency
- Hourly
- Estimated price
- €70–130
- Website
- https://www.sbb.ch/en
Train from Como S.Giovanni to Milano Porta Garibaldi
- Ave. Duration
- 49 min
- Frequency
- Twice a week
- Estimated price
- €22–45
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €23–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Como S.Giovanni to Milano Porta Garibaldi
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Mannheim Central Bus Station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Twice a week
- Estimated price
- €35–70
- Website
- https://marinobus.it/en/
- Phone
- +39 02 3008 9000
- mail@autostradale.it
- Website
- autostradale.it
Bus from San Donato - Nuova Autostazione to P.Za D'Azeglio
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €22–35
- Website
- https://autostradale.it/?lang=en-GB
- Standard Rate
- €25–35
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Frankfurt central train station to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 40m
- Frequency
- Twice daily
- Estimated price
- €45–120
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Pisa
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €8–11
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Italy
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More Questions & Answers
Mainz to Pisa bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Mainz to Pisa train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Pisa is 942 km. It takes approximately 9h 5m to drive from Mainz to Pisa.
Book your Mainz to Pisa train tickets online with Omio.
Book your Mainz to Pisa bus tickets online with Omio and FlixBus.
There are 4337+ hotels available in Pisa.

































































