There are 8 ways to get from Mainz to Pisa by plane, train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Pisa International Airport
best- Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
3h 58m€105–252Bus
cheapest- Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus N77 / ...
- Take the bus from Florence Villa Constanza Bus Station to Pisabus N538 / ...
20h 35m€83–155Train
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Pisa Centraletrain Re
12h 52m€123–686Drive 941.9 km
- Drive from Mainz to Pisacar 941.9 km
9h 4m€150–217Fly to Florence Peretola Airport, train
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze Rifredi to Pisa Centraletrain
5h 50m€135–329Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
6h 17m€123–295Train via Zurich
- Take the train from Mainz Hbf to Zürich HBtrain
- Take the train from Zürich HB to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Pisa Centraletrain Ic
15h 48m€174–484Train via Zurich #2
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim Hbf to Zuerich Hbtrain Ec
- Take the train from Zürich HB to Cadenazzotrain
- Take the train from Cadenazzo to Milano Centraletrain
- Take the train from Milano Centrale to Pisa Centraletrain Ic
18h 35m€175–339
Mainz to Pisa by train
Questions & Answers
The cheapest way to get from Mainz to Pisa is to bus which costs €80 - €160 and takes 20h 35m.
The fastest way to get from Mainz to Pisa is to fly which takes 3h 58m and costs €100 - €260.
No, there is no direct bus from Mainz station to Pisa. However, there are services departing from Mainz central train station and arriving at Pisa via Frankfurt central train station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 20h 35m.
No, there is no direct train from Mainz to Pisa. However, there are services departing from Mainz, Hauptbahnhof and arriving at Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 12h 52m.
The distance between Mainz and Pisa is 746 km. The road distance is 941.9 km.
The best way to get from Mainz to Pisa without a car is to train which takes 12h 52m and costs €120 - €700.
It takes approximately 3h 58m to get from Mainz to Pisa, including transfers.
Mainz to Pisa bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Pisa train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Pisa is to fly which takes 3h 58m and costs €100 - €260. Alternatively, you can train, which costs €120 - €700 and takes 12h 52m, you could also bus, which costs €80 - €160 and takes 20h 35m.
What companies run services between Mainz, Germany and Pisa, Italy?
Air Dolomiti, KLM, and Transavia Holland fly from Frankfurt (FRA) to Pisa International Airport (PSA) twice daily. Alternatively, you can take a train from Mainz, Hauptbahnhof to Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 12h 52m.
- Website
- lufthansa.com
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €170–750
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €110–370
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- €130–370
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–650
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €150–700
- Website
- airdolomiti.it
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €170–750
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €130–370
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €150–650
- Website
- klm.com
Flights from Frankfurt to Pisa International Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 5m
- When
- Sunday, Tuesday, and Saturday
- Estimated price
- €75–380
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €120–430
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €90–330
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €13–45
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €45–170
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €13–20
- Website
- https://int.bahn.de/en
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- €7–17
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €28–65
- Website
- https://www.ns.nl/en
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- €50–110
- Website
- https://www.ns.nl/en
- Phone
- +43 (0) 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 3h 37m
- Frequency
- 4 times a week
- Estimated price
- €55–95
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Mannheim Hbf to Zuerich Hb
- Ave. Duration
- 4h 43m
- Frequency
- 4 times a week
- Estimated price
- €70–130
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €95–280
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–85
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €65–200
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–85
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 3h 54m
- Frequency
- 3 times a day
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 3h 54m
- Frequency
- 3 times a day
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 4h 12m
- Frequency
- Every 2 hours
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 4h 12m
- Frequency
- Every 2 hours
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 58m
- Frequency
- Twice daily
- Estimated price
- €35–75
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- €11–22
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–16
- Website
- https://www.trenitalia.com/en.html
Train from Firenze Rifredi to Pisa Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Every 15 minutes
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–16
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- €35–60
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- €35–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 58 580 70 70
- Website
- sob.ch
Train from Zürich HB to Cadenazzo
- Ave. Duration
- 3h 7m
- Frequency
- Every 4 hours
- Estimated price
- €55–90
- Schedules at
- sob.ch
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Cadenazzo to Milano Centrale
- Ave. Duration
- 1h 38m
- Frequency
- Hourly
- Estimated price
- €7–9
- Website
- https://www.trenord.it/en/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Frankfurt central train station to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 40m
- Frequency
- Twice daily
- Estimated price
- €75–140
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Pisa
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- €5–10
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
More Questions & Answers
Mainz to Pisa bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Mainz to Pisa train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Pisa is 942 km. It takes approximately 9h 4m to drive from Mainz to Pisa.
Book your Mainz to Pisa train tickets online with Omio.
Book your Mainz to Pisa bus tickets online with Omio and FlixBus.
There are 4885+ hotels available in Pisa.






























































