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How to get fromMainz to Pisaby plane, train (Trenitalia), bus, car, or train

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There are 8 ways to get from Mainz to Pisa by plane, train (Trenitalia), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Pisa International Airport

    best
    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    3h 59m
    €106–252

  2. Bus via Milan

    cheapest
    1. Take the bus from Mainz central train station to Milanbus bus FlixBus 476
    2. Take the bus from Milan to Pisabus bus FlixBus 507
    19h 35m
    €86–139

  3. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Pisa Centraletrain train Re
    12h 56m
    €122–688

  4. Bus

    1. Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Pisabus bus 443 / ...
    19h 9m
    €146–200

  5. Drive 941.9 km

    1. Drive from Mainz to Pisacar car 941.9 km
    9h 4m
    €147–213

  6. Fly to Florence Peretola Airport, train

    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    5h 54m
    €137–300

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    6h 19m
    €120–295

  8. Train via Zurich

    1. Take the train from Mainz Hbf to Zürich HBtrain train
    2. Take the train from Zürich HB to Luganotrain train Ec / ...
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Pisa Centraletrain train Ic
    15h 51m
    €168–462

Mainz to Pisa by train

Calendar76Weekly Trains
Duration12h 56mAverage Duration
Ticket€122Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Pisa.ExpandLaunch map view
  • Distance: 746.2 km
  • Duration: 3h 59m

What companies run services between Mainz, Germany and Pisa, Italy?

Air Dolomiti flies from Frankfurt (FRA) to Pisa International Airport (PSA) twice daily. Alternatively, you can take a train from Mainz, Hauptbahnhof to Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 12h 56m.

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