There are 8 ways to get from Mainz to Pisa by plane, train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Pisa International Airport
best- Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
3h 58m€102–262Bus via Milan
cheapest- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milan to Pisabus FlixBus 507
19h 35m€91–141Train
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Pisa Centraletrain Re
12h 57m€116–378Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Pisabus 443 / ...
19h€142–206Drive 941.9 km
- Drive from Mainz to Pisacar 941.9 km
9h 4m€152–219Fly to Florence Peretola Airport, train
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
5h 53m€133–307Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
6h 18m€120–297Train via Zurich
- Take the train from Mainz Hbf to Zürich HBtrain
- Take the train from Zürich HB to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Pisa Centraletrain Ic
15h 54m€165–298
Mainz to Pisa by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Pisa is to bus via Milan which costs €90 - €150 and takes 19h 35m.
The fastest way to get from Mainz to Pisa is to fly which takes 3h 58m and costs €100 - €270.
No, there is no direct bus from Mainz to Pisa. However, there are services departing from Wiesbaden-Mainz-Kastel Bahnhof and arriving at Pisa via Wiesbaden Gartenfeldstraße P+R and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 19h.
No, there is no direct train from Mainz to Pisa. However, there are services departing from Mainz, Hauptbahnhof and arriving at Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 12h 57m.
The distance between Mainz and Pisa is 746 km. The road distance is 941.9 km.
The best way to get from Mainz to Pisa without a car is to train which takes 12h 57m and costs €110 - €380.
It takes approximately 3h 58m to get from Mainz to Pisa, including transfers.
Mainz to Pisa bus services, operated by Onebus, depart from Wiesbaden Gartenfeldstraße P+R station.
Mainz to Pisa train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Pisa is to fly which takes 3h 58m and costs €100 - €270. Alternatively, you can train, which costs €110 - €380 and takes 12h 57m, you could also bus, which costs €140 - €210 and takes 19h.
What companies run services between Mainz, Germany and Pisa, Italy?
Air Dolomiti flies from Frankfurt (FRA) to Pisa International Airport (PSA) twice daily. Alternatively, you can take a train from Mainz, Hauptbahnhof to Pisa Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 12h 57m.
- Website
- lufthansa.com
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €160–550
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €120–600
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €180–650
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €160–550
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €13–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 5m
- Frequency
- Once a week
- Estimated price
- €130–190
- Website
- Onebus
Want to know more about travelling around Italy
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Booking & Getting There
Mainz to Pisa bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Mainz to Pisa train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Pisa is 942 km. It takes approximately 9h 4m to drive from Mainz to Pisa.
Book your Mainz to Pisa train tickets online with Omio.
Book your Mainz to Pisa bus tickets online with Omio.
There are 4596+ hotels available in Pisa.





