Mainz to Rome Trains

Mainz to Rome trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Mainz and Rome takes 14h 34m and the fastest train takes 11h 33m. The train service runs several times per day from Mainz to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 34m
Duration: 1,232 km
Distance: €258
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Roma Terminitrain

12h 48m

€143–407

Mainz to Rome train times

Trains run every 4 hours between Mainz and Rome. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Rome at 3:19 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 14h 34m. The schedules shown below are for the next available departures.

Departing Thursday, October 8, 2026

7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
1:13 PM → 9:19 AM
Arrives next day
20h 6m • 4 changes
Show more

Departing Friday, October 9, 2026

5:40 AM → 5:30 PM
11h 50m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Saturday, October 10, 2026

1:38 AM → 3:19 PM
13h 41m • 4 changes
5:40 AM → 5:30 PM
11h 50m • 4 changes
6:56 AM → 7:19 PM
12h 23m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
Show more

Departing Sunday, October 11, 2026

1:38 AM → 3:19 PM
13h 41m • 4 changes
5:40 AM → 5:30 PM
11h 50m • 4 changes
6:56 AM → 7:19 PM
12h 23m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
Show more

Departing Monday, October 12, 2026

5:40 AM → 5:30 PM
11h 50m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Tuesday, October 13, 2026

5:40 AM → 5:30 PM
11h 50m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Wednesday, October 14, 2026

5:40 AM → 5:30 PM
11h 50m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes

Frequently asked questions

Want to know about travelling from Mainz to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Find Transport to Rome

Trip Overview

Train

Mainz to Rome train times

Departing Thursday, October 8, 2026

7:46 AM → 7:19 PM

9:13 AM → 9:05 PM

11:17 AM → 11:24 PM

1:13 PM → 9:19 AMArrives next day

Departing Friday, October 9, 2026

5:40 AM → 5:30 PM

7:46 AM → 7:19 PM

9:13 AM → 9:05 PM

11:17 AM → 11:24 PM

Departing Saturday, October 10, 2026

1:38 AM → 3:19 PM

5:40 AM → 5:30 PM

6:56 AM → 7:19 PM

9:13 AM → 9:05 PM

Departing Sunday, October 11, 2026

1:38 AM → 3:19 PM

5:40 AM → 5:30 PM

6:56 AM → 7:19 PM

9:13 AM → 9:05 PM

Departing Monday, October 12, 2026

5:40 AM → 5:30 PM

7:46 AM → 7:19 PM

9:13 AM → 9:05 PM

11:17 AM → 11:24 PM

Departing Tuesday, October 13, 2026

5:40 AM → 5:30 PM

7:46 AM → 7:19 PM

9:13 AM → 9:05 PM

11:17 AM → 11:24 PM

Departing Wednesday, October 14, 2026

5:40 AM → 5:30 PM

7:46 AM → 7:19 PM

9:13 AM → 9:05 PM

11:17 AM → 11:24 PM

Frequently asked questions

What companies run services between Mainz, Germany and Rome, Italy?

Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof

Train from Mannheim, Hauptbahnhof to Basel SBB

Train from Frankfurt to München Hbf

Where to next?

Train trips from Mainz

Train trips to Rome

Alternative transport options

1:13 PM → 9:19 AM
Arrives next day