The average train between Pisa and Siena takes 1h 49m and the fastest train takes 1h 29m. There is an hourly train service from Pisa to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa and Siena. The earliest departure is at 5:31 AM in the morning, and the last departure from Pisa is at 8:56 PM which arrives into Siena at 11:16 PM. All services require a transfer, and take on average 1h 49m. The schedules shown below are for the next available departures.

1h 50m • 1 change

1h 51m • 1 change

1h 47m • 1 change

1h 38m • 1 change

2h • 1 change

2h 8m • 1 change

2h 4m • 1 change

1h 47m • 1 change

2h • 1 change

2h 8m • 1 change

2h 4m • 1 change

1h 47m • 1 change
Want to know about travelling from Pisa to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Siena. However, there are services departing from Pisa station and arriving at Siena station via Empoli. The journey, including transfers, takes approximately 1h 49m.
Pisa to Siena train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Siena train services, operated by Trenitalia, arrive at Siena station.
Book your Pisa to Siena train tickets online with Trenitalia.
The distance between Pisa and Siena is 86.4 km. The road distance is 110 km.
You can take a train from Pisa Centrale to Siena via Empoli in around 2h 11m.