The average train between Mainz and Palermo takes 35h 46m and the fastest train takes 35h 36m. The train runs, on average, 6 times per week from Mainz to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between Mainz and Palermo. The earliest departure is at 7:04 AM in the morning, and the last departure from Mainz is at 7:29 AM which arrives into Palermo at 7:08 PM. All services require a transfer at Frankfurt and take an average of 35h 46m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Palermo. However, there are services departing from Mainz station and arriving at Palermo station via Chiasso. The journey, including transfers, takes approximately 35h 46m.
Mainz to Palermo train services, operated by vlexx, depart from Frankfurt station.
Mainz to Palermo train services, operated by vlexx, arrive at Palermo Centrale station.
Book your Mainz to Palermo train tickets online with vlexx, Swiss Federal Railways (SBB CFF FFS) and 3 other operators.
The distance between Mainz and Palermo is 1,377.6 km. The road distance is 2,149 km.
You can take a train from Mainz, Römisches Theater to Palermo Centrale via Frankfurt, Chiasso, Milano Centrale, and Roma Termini in around 25h 54m.
