Rome2Rio

Mainz to Palermo trains

Find Transport to Palermo

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average train between Mainz and Palermo takes 30h 56m and the fastest train takes 29h 44m. The train service runs several times per day from Mainz to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

30h 56m
Duration
2,126 km
Distance
€384
Average price
Twice daily
Frequency

Mainz to Palermo train times

Trains run twice daily between Mainz and Palermo. The earliest departure is at 11:14 AM in the morning, and the last departure from Mainz is at 5:14 PM which arrives into Palermo at 10:58 PM. All services require a transfer at Frankfurt and take an average of 30h 56m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity29h 44m • 5 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity31h 59m • 5 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity29h 44m • 5 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity31h 59m • 5 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity29h 44m • 5 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity31h 56m • 5 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity29h 44m • 5 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity31h 59m • 5 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity29h 44m • 5 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity31h 59m • 5 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity29h 44m • 5 changes

Frequently asked questions

Want to know about travelling from Mainz to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Palermo.ExpandLaunch map view
  • Distance: 2,126 km
  • Duration: 30h 56m

What companies run services between Mainz, Germany and Palermo, Italy?

You can take a train from Mainz, Römisches Theater to Palermo Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 25h 35m.

Operators