The average bus between Mainz and Palermo takes 2d 4h and the fastest bus takes 2d 3h. The bus runs, on average, 5 times per week from Mainz to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Mainz and Palermo. The earliest departure is at 5:10 AM in the morning, and the last departure from Mainz is at 6:10 AM which arrives into Palermo at 11:00 AM. All services require a transfer at Frankfurt(Main)Hbf and take an average of 2d 4h. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Palermo. However, there are services departing from Mühlheim am Main station and arriving at Palermo Piazza Cairoli station via Palermo Piazza Cairoli station. The journey, including transfers, takes approximately 2 days 4h.
Mainz to Palermo bus services, operated by Onebus, depart from Mühlheim am Main station.
Mainz to Palermo bus services, operated by Onebus, arrive at Palermo Piazza Cairoli station.
Book your Mainz to Palermo bus tickets online with Omio.
The distance between Mainz and Palermo is 1377.6 km.
Onebus operates a bus from Mühlheim am Main to Palermo Piazza Cairoli once a week. Tickets cost €250–350 and the journey takes 28h 19m.