The average train between Mainz and Italy takes 14h 57m and the fastest train takes 12h 8m. The train service runs several times per day from Mainz to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Italy. The earliest departure is at 1:42 AM at night, and the last departure from Mainz is at 11:12 PM which arrives into Italy at 3:19 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 14h 57m. The schedules shown below are for the next available departures.




12h 19m • 4 changes




12h 8m • 4 changes




12h 27m • 4 changes
Arrives next day




20h 22m • 4 changes




15h 48m • 4 changes




12h 19m • 4 changes




12h 8m • 4 changes




12h 27m • 4 changes




13h 37m • 4 changes




12h 19m • 4 changes




12h 8m • 4 changes




12h 27m • 4 changes




12h 12m • 4 changes




12h 19m • 4 changes




12h 8m • 4 changes




12h 27m • 4 changes




12h 12m • 4 changes




12h 19m • 4 changes




12h 8m • 4 changes




12h 27m • 4 changes




12h 12m • 4 changes




12h 19m • 4 changes




12h 27m • 4 changes
Arrives next day




20h 22m • 4 changes
Want to know about travelling from Mainz to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Italy. However, there are services departing from Mainz station and arriving at Italy station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 14h 57m.
Mainz to Italy train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Italy train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Roma Termini station.
Book your Mainz to Italy train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 4 other operators.
The distance between Mainz and Italy is 883.4 km. The road distance is 1,231 km.
You can take a train from Mainz, Römisches Theater to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 13h 17m.