Rome2Rio

Mainz to Italy trains

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Trip Overview

The average train between Mainz and Italy takes 15h 36m and the fastest train takes 11h 51m. The train service runs several times per day from Mainz to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 36m
Duration
1,261 km
Distance
€264
Average price
Every 4 hours
Frequency

Mainz to Italy train times

Trains run every 4 hours between Mainz and Italy. The earliest departure is at 7:05 AM in the morning, and the last departure from Mainz is at 9:14 PM which arrives into Italy at 1:24 PM. All services require a transfer at Frankfurt and take an average of 15h 36m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno17h 46m • 4 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno20h 5m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 6m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno11h 51m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 10m • 4 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno20h 5m • 4 changes
  • Show more

Departing Friday, November 13, 2026

  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 6m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno11h 51m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 10m • 4 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno20h 5m • 4 changes
  • Show more

Departing Saturday, November 14, 2026

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    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 14m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno11h 51m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 10m • 4 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno20h 5m • 4 changes
  • Show more

Departing Sunday, November 15, 2026

  •  → 

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 14m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno11h 51m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 10m • 4 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno20h 5m • 4 changes
  • Show more

Departing Monday, November 16, 2026

  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 6m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno11h 51m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 10m • 4 changes
  •  → 

    Arrives next day

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno20h 5m • 4 changes
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 6m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno11h 51m • 4 changes
  •  → 

    vlexxDeutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno12h 10m • 4 changes

Frequently asked questions

Want to know about travelling from Mainz to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Italy.ExpandLaunch map view
  • Distance: 1,260.5 km
  • Duration: 15h 36m

What companies run services between Mainz, Germany and Italy?

You can take a train from Mainz, Römisches Theater to Roma Termini via Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 13h 4m.

Operators