The average train between Mainz and Italy takes 15h 40m and the fastest train takes 11h 50m. The train service runs several times per day from Mainz to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Italy. The earliest departure is at 5:40 AM in the morning, and the last departure from Mainz is at 11:08 PM which arrives into Italy at 4:19 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 15h 40m. The schedules shown below are for the next available departures.
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12h 52m • 4 changes
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20h 6m • 4 changes




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20h 6m • 4 changes
Want to know about travelling from Mainz to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Italy. However, there are services departing from Mainz station and arriving at Italy station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 15h 40m.
Mainz to Italy train services, operated by Süwex, depart from Mainz, Hauptbahnhof station.
Mainz to Italy train services, operated by Süwex, arrive at Roma Termini station.
Book your Mainz to Italy train tickets online with Süwex, Deutsche Bahn Intercity (DB IC) and 5 other operators.
The distance between Mainz and Italy is 883.4 km. The road distance is 1,232 km.
You can take a train from Mainz, Hauptbahnhof to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 12h 35m.