Mainz to Italy Trains

Trip Overview

The average train between Mainz and Italy takes 15h 10m and the fastest train takes 11h 33m. The train service runs several times per day from Mainz to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 10m
Duration: 1,232 km
Distance: €265
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Roma Terminitrain

12h 34m

€152–419

Mainz to Italy train times

Trains run every 4 hours between Mainz and Italy. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Italy at 4:19 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 15h 10m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

10:18 PM → 4:19 PM
Arrives next day
18h 1m • 4 changes

Departing Thursday, October 22, 2026

5:40 AM → 5:30 PM
11h 50m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Friday, October 23, 2026

5:40 AM → 5:30 PM
11h 50m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Saturday, October 24, 2026

1:38 AM → 4:19 PM
14h 41m • 4 changes
1:43 AM → 5:30 PM
15h 47m • 4 changes
6:22 AM → 7:19 PM
12h 57m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
Show more

Departing Sunday, October 25, 2026

2:38 AM → 4:19 PM
14h 41m • 4 changes
6:22 AM → 7:19 PM
12h 57m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Monday, October 26, 2026

1:43 AM → 5:30 PM
15h 47m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Tuesday, October 27, 2026

1:43 AM → 5:30 PM
15h 47m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes
Show more

Departing Wednesday, October 28, 2026

1:43 AM → 5:30 PM
15h 47m • 4 changes
7:46 AM → 7:19 PM
11h 33m • 4 changes
9:13 AM → 9:05 PM
11h 52m • 4 changes
11:17 AM → 11:24 PM
12h 7m • 4 changes

Frequently asked questions

Want to know about travelling from Mainz to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.