Mainz to Florence trains

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Trip Overview

The average train between Mainz and Florence takes 13h 45m and the fastest train takes 10h 18m. The train service runs several times per day from Mainz to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 45m
Duration: 956 km
Distance: €240
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Firenze S.M.N.train Fr

11h 31m

€113–418

Mainz to Florence train times

Trains run every 4 hours between Mainz and Florence. The earliest departure is at 1:43 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Florence at 2:04 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 13h 45m. The schedules shown below are for the next available departures.

Departing Tuesday, October 27, 2026

1:43 AM → 4:04 PM
14h 21m • 4 changes
7:46 AM → 6:04 PM
10h 18m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes
Show more

Departing Wednesday, October 28, 2026

1:43 AM → 4:04 PM
14h 21m • 4 changes
7:46 AM → 6:04 PM
10h 18m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes
Show more

Departing Thursday, October 29, 2026

1:43 AM → 4:04 PM
14h 21m • 4 changes
7:46 AM → 6:04 PM
10h 18m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes
Show more

Departing Friday, October 30, 2026

2:01 AM → 4:04 PM
14h 3m • 4 changes
7:46 AM → 6:04 PM
10h 18m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes
Show more

Departing Saturday, October 31, 2026

5:40 AM → 4:04 PM
10h 24m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes
1:13 PM → 7:04 AM
Arrives next day
17h 51m • 4 changes
Show more

Departing Sunday, November 1, 2026

5:40 AM → 4:04 PM
10h 24m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes
1:13 PM → 7:04 AM
Arrives next day
17h 51m • 4 changes
Show more

Departing Monday, November 2, 2026

5:40 AM → 4:04 PM
10h 24m • 4 changes
7:46 AM → 6:04 PM
10h 18m • 4 changes
9:13 AM → 8:04 PM
10h 51m • 4 changes
11:17 AM → 10:04 PM
10h 47m • 4 changes

Frequently asked questions

Want to know about travelling from Mainz to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.