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How to get fromMainz to Palermoby plane, train (Trenitalia), car, car ferry, bus or train

Find Transport to Palermo

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There are 8 ways to get from Mainz to Palermo by plane, train (Trenitalia), car, car ferry, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt

    best
    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 41m
    €100–288
  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Milano, Autostazione Lampugnanobus bus 476
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    35h
    €81–273
  3. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    3. Take the train from Basel SBB to Zürich HBtrain train Ice / ...
    4. Take the train from Zürich HB to Milano Centraletrain train Ec
    5. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    6. Take the train from Roma Termini to Palermo Centraletrain train Ic
    25h 50m
    €225–575
  4. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 27m
    €185–320
  5. Train to Stuttgart Airport, fly

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane plane STR - PMO
    7h 14m
    €120–362
  6. Bus to Hahn, fly

    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus bus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)plane plane HHN - PMO
    6h 37m
    €110–316
  7. Train, car ferry

    1. Take the train from Mainz Hbf to Zürich HBtrain train
    2. Take the train from Zürich HB to Genova P. Principetrain train Ec
    3. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    36h 3m
    €270–637
  8. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the bus from Mannheim Central Bus Station to Milanbus bus
    3. Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus bus
    36h 20m
    €104–175

Mainz to Palermo by train

Calendar8Weekly Trains
Duration25h 50mAverage Duration
Ticket€225Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Palermo, Italy?

Lufthansa, Air Dolomiti, and two other airlines fly from Frankfurt (FRA) to Palermo Airport (PMO) 4 times a day. Alternatively, you can take a train from Mainz, Römisches Theater to Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Zürich HB, Milano Centrale, and Roma Termini in around 25h 50m.

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