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How to get fromMainz to Palermoby plane, train (Trenitalia), car, car ferry, bus or train

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There are 9 ways to get from Mainz to Palermo by plane, train (Trenitalia), car, car ferry, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Palermo Airport

    best
    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)planeFRA - PMO
    5h 39m
    €95–238
  2. Bus to Hahn, fly to Palermo Airport

    cheapest
    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)planeHHN - PMO
    6h 35m
    €85–316
  3. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS6 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain20 / ...
    3. Take the train from Basel SBB to Zürich HBtrainIce / ...
    4. Take the train from Zürich HB to Milan RogoredotrainEc
    5. Take the train from Milan Rogoredo to Roma Terminitrain
    6. Take the train from Roma Termini to Palermo CentraletrainIc
    26h 12m
    €225–585
  4. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry
    28h 26m
    €183–308
  5. Bus

    1. Take the bus from Mainz central train station to Milano, Autostazione Lampugnanobus476
    2. Take the bus from Milano, Autostazione Lampugnano to PalermobusN597
    35h 10m
    €92–275
  6. Fly Frankfurt to Catania–Fontanarossa Airport, bus

    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)planeFRA - CTA
    2. Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
    7h 56m
    €108–310
  7. Train to Cologne Bonn Airport, fly to Palermo Airport

    1. Take the train from Frankfurt to Siegburg Bftrain
    2. Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)planeCGN - PMO
    7h 28m
    €108–393
  8. Train, car ferry

    1. Take the train from Mainz Hbf to Zürich HBtrain
    2. Take the train from Zürich HB to Genova P. PrincipetrainEc
    3. Take the car ferry from Port of Genoa to Port of Palermocarferry
    36h 3m
    €270–627
  9. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS6 / ...
    2. Take the bus from Mannheim Central Bus Station to Milanbus
    3. Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
    36h 22m
    €104–160

Mainz to Palermo by train

Calendar7Weekly Trains
Duration26h 12mAverage Duration
Ticket€225Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Palermo, Italy?

Lufthansa, Swiss, and two other airlines fly from Frankfurt (FRA) to Palermo Airport (PMO) once daily. Alternatively, you can take a train from Mainz, Römisches Theater to Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Zürich HB, Milan Rogoredo, and Roma Termini in around 26h 12m.

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