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How to get fromMainz to Palermoby plane, train (Trenitalia), car, car ferry, bus, train or night train

Find Transport to Palermo

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There are 8 ways to get from Mainz to Palermo by plane, train (Trenitalia), car, car ferry, bus, train, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt

    best
    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 41m
    €95–289
  2. Bus to Hahn, fly

    cheapest
    1. Take the bus from Mainz, Hauptbahnhof to Hahnbus bus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)plane plane HHN - PMO
    6h 32m
    €68–223
  3. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    3. Take the train from Basel SBB to Domodossolatrain train Ec
    4. Take the train from Domodossola to Milano Centraletrain train
    5. Take the train from Milano Centrale to Roma Terminitrain train
    6. Take the train from Roma Termini to Palermo Centraletrain train Ic
    26h 33m
    €288–742
  4. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 27m
    €221–331
  5. Bus

    1. Take the bus from Mainz central train station to Milanbus bus FlixBus 476
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    35h
    €148–263
  6. Train to Cologne Bonn Airport, fly

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane plane CGN - PMO
    7h 30m
    €96–351
  7. Train, night train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 22 / ...
    3. Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    4. Take the train from Venezia Mestre to Roma Terminitrain train
    5. Take the train from Roma Termini to Palermo Centraletrain train Ic
    32h 39m
    €217–528
  8. Bus, car ferry

    1. Take the bus from Frankfurt - Airport Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus bus BlaBlaCar Bus
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    36h 51m
    €150–257

Mainz to Palermo by train

Calendar1Weekly Trains
Duration26h 33mAverage Duration
Ticket€288Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Palermo, Italy?

Lufthansa, ITA Airways, and Swiss fly from Frankfurt (FRA) to Palermo Airport (PMO) 5 times a day. Alternatively, you can take a train from Mainz, Römisches Theater to Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Domodossola, Milano Centrale, and Roma Termini in around 26h 33m.

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