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How to get fromMainz to Palermoby plane, train (Trenitalia), car, car ferry, bus, or train

Find Transport to Palermo

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There are 11 ways to get from Mainz to Palermo by plane, train (Trenitalia), car, car ferry, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Palermo Airport

    best
    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 45m
    €94–279

  2. Bus to Hahn, fly to Palermo Airport

    cheapest
    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus bus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)plane plane HHN - PMO
    6h 32m
    €71–262

  3. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    6. Take the train from Roma Termini to Palermo Centraletrain train Ic
    25h 25m
    €244–873

  4. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 27m
    €217–323

  5. Bus

    1. Take the bus from Mainz central train station to Milanbus bus FlixBus 476
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    35h
    €112–276

  6. Train, train to Stuttgart Airport, fly to Palermo Airport

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    3. Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane plane STR - PMO
    7h 17m
    €101–341

  7. Train to Cologne Bonn Airport, fly to Palermo Airport

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane plane CGN - PMO
    7h 45m
    €97–374

  8. Fly Frankfurt to Catania–Fontanarossa Airport, bus

    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    2. Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus bus
    8h 21m
    €92–296

  9. Train via Mainz, Hauptbahnhof

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Roma Terminitrain train
    6. Take the train from Roma Termini to Palermo Centraletrain train Ic
    25h 31m
    €244–853

  10. Train, car ferry

    1. Take the train from Frankfurt to Como S. Giovannitrain train Ec
    2. Take the train from Como S. Giovanni to Milano Centraletrain train S11
    3. Take the train from Milano Centrale to Genova P.Za Principetrain train Ic
    4. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    34h 9m
    €359–894

  11. Train, bus

    1. Take the train from Mainz Hbf to Zürich HBtrain train
    2. Take the bus from Zürich Bus Station to San Donato Milanesebus bus 36
    3. Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus bus
    35h 37m
    €124–233

Mainz to Palermo by train

Calendar8Weekly Trains
Duration25h 25mAverage Duration
Ticket€244Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Palermo.ExpandLaunch map view
  • Distance: 1,424.5 km
  • Duration: 5h 45m

What companies run services between Mainz, Germany and Palermo, Italy?

Lufthansa, ITA Airways, and Swiss fly from Frankfurt (FRA) to Palermo Airport (PMO) every 4 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 25h 25m.

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