The average train between Mainz and Madrid takes 24h 33m and the fastest train takes 22h 52m. The train service runs several times per day from Mainz to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Mainz and Madrid. The earliest departure is at 7:51 AM in the morning, and the last departure from Mainz is at 6:00 PM which arrives into Madrid at 4:52 PM. All services require a transfer at Saarbrücken Hbf and take an average of 24h 33m. The schedules shown below are for the next available departures.
Arrives next day




25h 6m • 4 changes
Arrives next day




22h 52m • 4 changes
Arrives next day




25h 6m • 4 changes
Arrives next day




22h 52m • 4 changes
Arrives next day




25h 6m • 4 changes
Arrives next day




22h 52m • 4 changes
Want to know about travelling from Mainz to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Madrid. However, there are services departing from Mainz station and arriving at Madrid station via Saarbrücken Hbf. The journey, including transfers, takes approximately 24h 33m.
Mainz to Madrid train services, operated by vlexx, depart from Mainz, Hauptbahnhof station.
Mainz to Madrid train services, operated by vlexx, arrive at Madrid-Puerta de Atocha-Almudena Grandes station.
Book your Mainz to Madrid train tickets online with vlexx, Société Nationale des Chemins de fer Français (SNCF) and 4 other operators.
The distance between Mainz and Madrid is 1,415.4 km. The road distance is 2,235 km.
You can take a train from Mainz, Hauptbahnhof to Madrid-Puerta de Atocha-Almudena Grandes via Saarbrücken Hbf, Paris l'Est, Paris Nord, Paris Gare De Lyon, and Barcelona-Sants in around 16h 38m.