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How to get fromMainz to Madridby plane, train (TGV, Renfe, Ouigo), bus, car, or train

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There are 6 ways to get from Mainz to Madrid by plane, train (TGV, Renfe, Ouigo), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt

    best
    1. Fly from Frankfurt (FRA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FRA - MAD
    5h 28m
    €84–244
  2. Train

    1. Take the train from Frankfurt to Bruxelles Miditrain train 79
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Lyon Part Dieutrain train Tgv
    3. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    4. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    18h
    €333–642
  3. Bus

    1. Take the bus from Frankfurt - Airport Bus Station to Estación Sur de Autobusesbus bus BlaBlaCar Bus
    30h 41m
    €166–280
  4. Drive  1,735.4 km

    1. Drive from Mainz to Madridcar car 1,735.4 km
    17h 16m
    €323–466
  5. Train to Düsseldorf International Airport, fly

    1. Take the train from Mainz Hbf to Duesseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane DUS - MAD
    7h 39m
    €97–304
  6. Bus via Valladolid

    1. Take the bus from Mainz central train station to Valladolidbus bus FlixBus N1151
    2. Take the bus from Valladolid to Madrid Moncloabus bus ALSA - Val-Mad / ...
    31h 3m
    €179–264

Mainz to Madrid by train

Calendar14Weekly Trains
Duration18hAverage Duration
Ticket€333Cheapest Price
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Comparing Your Travel Options

What companies run services between Mainz, Germany and Madrid, Spain?

Iberia, Lufthansa, and three other airlines fly from Frankfurt (FRA) to Adolfo Suárez Madrid–Barajas Airport (MAD) every 3 hours. Alternatively, you can take a train from Mainz, Römisches Theater to Madrid-Puerta de Atocha-Almudena Grandes via Frankfurt, Bruxelles Midi, Brussel-Zuid / Bruxelles-Midi, Lyon Part Dieu, and Barcelona-Sants in around 18h.

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