The average train between Mainz and Essen takes 3h 18m and the fastest train takes 2h 41m. The train service runs several times per day from Mainz to Essen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mainz and Essen. The earliest departure is at 1:14 PM in the afternoon, and the last departure from Mainz is at 9:14 PM which arrives into Essen at 1:55 AM. All services require a transfer, and take on average 3h 18m. The schedules shown below are for the next available departures.

2h 45m • 1 change
3h 19m • 1 changeArrives next day

4h 3m • 1 change
4h 18m • 1 change
2h 41m • 1 change
2h 57m • 1 change
3h 6m • 1 change
4h 18m • 1 change
2h 41m • 1 change
2h 57m • 1 change
3h 6m • 1 change
4h 18m • 1 change
2h 41m • 1 change
2h 58m • 1 change
3h 7m • 1 changeWant to know about travelling from Mainz to Essen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Essen. However, there are services departing from Mainz station and arriving at Essen station via Essen Hbf. The journey, including transfers, takes approximately 3h 18m.
Mainz to Essen train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Essen train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Essen Hbf station.
Book your Mainz to Essen train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mainz and Essen is 186.4 km. The road distance is 274 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Essen Hbf every 30 minutes. Tickets cost €45–90 and the journey takes 1h 41m.