The average train between Mainz and Mayen takes 2h 26m and the fastest train takes 2h 23m. There is a train service every few hours from Mainz to Mayen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Mayen. The earliest departure is at 5:47 AM in the morning, and the last departure from Mainz is at 8:19 PM which arrives into Mayen at 10:44 PM. All services require a transfer, and take on average 2h 26m. The schedules shown below are for the next available departures.

2h 23m • 1 change

2h 23m • 1 change

2h 25m • 1 change

2h 24m • 1 change

2h 56m • 1 change

2h 26m • 1 change

2h 23m • 1 change

2h 23m • 1 change

2h 56m • 1 change

2h 26m • 1 change

2h 23m • 1 change

2h 23m • 1 change

2h 56m • 1 change

2h 26m • 1 change

2h 23m • 1 change

2h 23m • 1 change
Want to know about travelling from Mainz to Mayen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Mayen. However, there are services departing from Mainz station and arriving at Mayen station via Koblenz Hbf. The journey, including transfers, takes approximately 2h 26m.
Mainz to Mayen train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz Hbf station.
Mainz to Mayen train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mayen Ostbahnhof station.
Book your Mainz to Mayen train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Trans Regio Deutsche Regionalbahn GmbH (MittelrheinBahn).
The distance between Mainz and Mayen is 84.4 km. The road distance is 132 km.
You can take a train from Mainz Hbf to Mayen Ostbahnhof via Koblenz Hauptbahnhof in around 2h 58m.