What is the cheapest way to get from Isernia to Palermo?

The cheapest way to get from Isernia to Palermo is to bus via Caserta which costs €35 - €60 and takes 12h.

What is the fastest way to get from Isernia to Palermo?

The fastest way to get from Isernia to Palermo is to train and fly which takes 5h 17m and costs €40 - €180.

Is there a direct bus between Isernia and Palermo?

No, there is no direct bus from Isernia to Palermo. However, there are services departing from Isernia and arriving at Palermo Terminal Bus via Caserta pzza Garibaldi. The journey, including transfers, takes approximately 12h.

Is there a direct train between Isernia and Palermo?

No, there is no direct train from Isernia to Palermo. However, there are services departing from Isernia and arriving at Palermo Centrale via Napoli Centrale. The journey, including transfers, takes approximately 12h 19m.

How far is it from Isernia to Palermo?

The distance between Isernia and Palermo is 465 km.

How do I travel from Isernia to Palermo without a car?

The best way to get from Isernia to Palermo without a car is to bus via Caserta which takes 12h and costs €35 - €60.

How long does it take to get from Isernia to Palermo?

It takes approximately 5h 17m to get from Isernia to Palermo, including transfers.

Where do I catch the Isernia to Palermo bus from?

Isernia to Palermo bus services, operated by FlixBus, depart from Isernia station.

Where do I catch the Isernia to Palermo train from?

Isernia to Palermo train services, operated by Trenitalia, depart from Isernia station.

Train or bus from Isernia to Palermo?

The best way to get from Isernia to Palermo is to bus via Caserta which takes 12h and costs €35 - €60. Alternatively, you can train, which costs €85 - €180 and takes 12h 19m.

Where does the Isernia to Palermo bus arrive?

Isernia to Palermo bus services, operated by FlixBus, arrive at Caserta Terminal Bus station.

Where does the Isernia to Palermo train arrive?

Isernia to Palermo train services, operated by Trenitalia, arrive at Napoli Centrale station.

How do I get a train ticket from Isernia to Palermo?

Book your Isernia to Palermo train tickets online with Omio.

How do I get a bus ticket from Isernia to Palermo?

Book your Isernia to Palermo bus tickets online with Omio.

Where can I stay near Palermo?

There are 6395+ hotels available in Palermo.

Isernia to Palermo - 8 ways to travel via train, plane, car, ferry, and bus

How to get fromIsernia to Palermo

Travel from

See all options

Search accommodation with Expedia

There are 8 ways to get from Isernia to Palermo by train, plane, car, ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train to Naples Airport, fly to Palermo Airport
best
1. Take the train from Isernia to Casertatrain
2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane NAP - PMO
5h 17m
€42–179
Bus via Caserta
cheapest
1. Take the bus from Isernia to Caserta Terminal Busbus 433
2. Take the bus from Caserta pzza Garibaldi to Palermo Terminal Busbus Autoservizi Salemi S201
12h
€37–56
Drive, ferry
1. Drive from Isernia to Naples Beverellocar
2. Take the ferry from Naples Beverello to Port of Palermoferry
9h 2m
€47–80
Train (Trenitalia)
1. Take the train from Isernia to Napoli Centraletrain Re
2. Take the train from Napoli Centrale to Palermo Centraletrain Ic
12h 19m
€86–176
Train to Fiumicino International Airport, fly to Palermo Airport
1. Take the train from Isernia to Roma Terminitrain
2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane FCO - PMO
5h 59m
€50–162
Train to Fiumicino International Airport, fly to Trapani Airport, bus
1. Take the train from Isernia to Roma Terminitrain
2. Fly from Fiumicino International Airport (FCO) to Trapani Airport (TPS)plane FCO - TPS
3. Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
7h 36m
€68–225
Train, ferry
1. Take the train from Isernia to Napoli Centraletrain Re
2. Take the ferry from Naples Beverello to Port of Palermoferry
10h 41m
€47–85
Bus
1. Take the bus from Isernia to Casello - A1 Ingresso Caianellobus 6
2. Take the bus from Casello - A1 Ingresso Caianello to Palermo Piazza Cairolibus
17h 55m

Isernia to Palermo by bus

7Weekly Buses

12hAverage Duration

€37Cheapest Price

See schedules

Questions & Answers

Map of how to get from Isernia to Palermo.

Launch map view

Distance: 464.5 km
Duration: 5h 17m

What companies run services between Isernia, Italy and Palermo, Italy?

You can take a bus from Isernia to Palermo Terminal Bus via Caserta Terminal Bus and Caserta pzza Garibaldi in around 12h. Alternatively, you can take a train from Isernia to Palermo Centrale via Napoli Centrale in around 12h 19m.

Airlines

Train operators

Bus operators

Ferry operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.