There are 8 ways to get from Isernia to Palermo by train, plane, car, ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Naples Airport, fly to Palermo Airport
best- Take the train from Isernia to Napoli Centraletrain
- Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane NAP - PMO
5h 17m€40–143Bus
cheapest- Take the bus from Isernia to Napoli, Autostazione Metroparkbus 6
- Take the bus from Napoli, Autostazione Metropark to Palermo Terminal Busbus Itabus
13h 20m€29–45Drive, ferry
- Drive from Isernia to Port of Naplescar
- Take the ferry from Port of Naples to Port of Palermoferry
10h 1m€57–80Bus via Caserta
- Take the bus from Isernia to Caserta Terminal Busbus 433
- Take the bus from Caserta Viale Vittorio Veneto to Palermo Via Tommaso Fazellobus Autoservizi Salemi S201
12h€35–62Train
- Take the train from Isernia to Napoli Centraletrain Re
- Take the train from Napoli Centrale to Palermo Centraletrain Ic
12h 30m€37–102Train to Fiumicino International Airport, fly to Palermo Airport
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane FCO - PMO
6h 15m€58–191Train to Naples Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Isernia to Napoli Centraletrain
- Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane NAP - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
7h 31m€48–166Train, ferry
- Take the train from Isernia to Napoli Centraletrain Re
- Take the ferry from Port of Naples to Port of Palermoferry
11h 49m€50–71
Isernia to Palermo by bus
Questions & Answers
The cheapest way to get from Isernia to Palermo is to bus which costs €28 - €45 and takes 13h 20m.
The fastest way to get from Isernia to Palermo is to train and fly which takes 5h 17m and costs €35 - €150.
No, there is no direct bus from Isernia to Palermo. However, there are services departing from Isernia and arriving at Palermo Via Tommaso Fazello via Caserta Viale Vittorio Veneto. The journey, including transfers, takes approximately 12h.
No, there is no direct train from Isernia to Palermo. However, there are services departing from Isernia and arriving at Palermo Centrale via Napoli Centrale. The journey, including transfers, takes approximately 12h 30m.
The distance between Isernia and Palermo is 476 km.
The best way to get from Isernia to Palermo without a car is to bus via Caserta which takes 12h and costs €35 - €65.
It takes approximately 5h 17m to get from Isernia to Palermo, including transfers.
Isernia to Palermo bus services, operated by FlixBus, depart from Isernia station.
Isernia to Palermo train services, operated by Trenitalia S.p.A., depart from Isernia station.
The best way to get from Isernia to Palermo is to bus via Caserta which takes 12h and costs €35 - €65. Alternatively, you can train, which costs €35 - €110 and takes 12h 30m.
What companies run services between Isernia, Italy and Palermo, Italy?
You can take a bus from Isernia to Palermo Via Tommaso Fazello via Caserta Terminal Bus and Caserta Viale Vittorio Veneto in around 12h. Alternatively, you can take a train from Isernia to Palermo Centrale via Napoli Centrale in around 12h 30m.
- Website
- ryanair.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €29–130
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €30–160
Flights from Naples Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €30–150
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €35–270
- Website
- flexflight.dk
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €35–270
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- €35–130
- Website
- easyjet.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €22–120
Flights from Naples Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €23–110
- Website
- volotea.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Thursday
- Estimated price
- €22–100
- Website
- tuifly.be
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €80–270
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Napoli Centrale
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Napoli Centrale to Palermo Centrale
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- €28–90
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Isernia to Caserta Terminal Bus
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- €6–18
- Website
- https://www.flixbus.co.uk
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- €10–19
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Caserta Viale Vittorio Veneto to Palermo Via Tommaso Fazello
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- €29–45
- Schedules at
- autoservizisalemi.it
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Schedules at
- saisautolinee.it
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Isernia to Napoli, Autostazione Metropark
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- €4–10
- Schedules at
- satiautobus.com
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Napoli, Autostazione Metropark to Palermo Terminal Bus
- Ave. Duration
- 10h 30m
- Frequency
- 3 times a week
- Estimated price
- €24–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port of Naples to Port of Palermo
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- €40–55
- Website
- https://www.grimaldi-lines.com/en/
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More Questions & Answers
Isernia to Palermo bus services, operated by FlixBus, arrive at Caserta Terminal Bus station.
Isernia to Palermo train services, operated by Trenitalia S.p.A., arrive at Napoli Centrale station.
Book your Isernia to Palermo bus tickets online with Omio.
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