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How to get fromIsernia to Palermoby train, plane, car, car ferry, bus or train (Trenitalia)

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There are 7 ways to get from Isernia to Palermo by train, plane, car, car ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Naples Airport, fly to Palermo Airport

    best
    1. Take the train from Isernia to Napoli Centraletrain train
    2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    5h 17m
    €39–144
  2. Bus

    cheapest
    1. Take the bus from Isernia to Napoli, Autostazione Metroparkbus bus 6
    2. Take the bus from Napoli, Autostazione Metropark to Palermo Terminal Busbus bus Itabus
    13h 20m
    €29–45
  3. Drive, car ferry

    1. Drive from Isernia to Port of Naplescar car
    2. Take the car ferry from Port of Naples to Port of Palermocarferry car ferry
    10h 1m
    €57–94
  4. Bus via Caserta

    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta Viale Vittorio Veneto to Palermo Via Tommaso Fazellobus bus Autoservizi Salemi S201
    12h
    €34–61
  5. Train (Trenitalia)

    1. Take the train from Isernia to Cassinotrain train Re
    2. Take the train from Cassino to Palermo Centraletrain train Ic
    12h 48m
    €61–96
  6. Train to Fiumicino International Airport, fly to Palermo Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane plane FCO - PMO
    6h 15m
    €58–191
  7. Train to Naples Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the train from Isernia to Napoli Centraletrain train
    2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane plane NAP - CTA
    3. Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus bus
    7h 31m
    €46–156

Isernia to Palermo by bus

Calendar7Weekly Buses
Duration12hAverage Duration
Ticket€34Cheapest Price
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Questions & Answers

What companies run services between Isernia, Italy and Palermo, Italy?

You can take a bus from Isernia to Palermo Via Tommaso Fazello via Caserta Terminal Bus and Caserta Viale Vittorio Veneto in around 12h. Alternatively, you can take a train from Isernia to Palermo Centrale via Cassino in around 12h 48m.

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