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Genoa to Isernia trains

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Trip Overview

The average train between Genoa and Isernia takes 14h 45m and the fastest train takes 12h 40m. The train runs, on average, 6 times per week from Genoa to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 45m
Duration
675 km
Distance
€106
Average price
6 times a week
Frequency

Genoa to Isernia train times

Trains run 6 times a week between Genoa and Isernia. The earliest departure is at 7:12 AM in the morning, and the last departure from Genoa is at 6:42 PM which arrives into Isernia at 7:52 PM. All services require a transfer, and take on average 14h 45m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Trenitalia FrecceTrenitalia12h 40m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Trenitalia FrecceTrenitalia12h 40m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Trenitalia FrecceTrenitalia12h 40m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Trenitalia FrecceTrenitalia12h 40m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Trenitalia FrecceTrenitalia12h 40m • 1 change
  •  → 

    Arrives next day

    Trenitalia FrecceTrenitalia25h 10m • 1 change

Frequently asked questions

Want to know about travelling from Genoa to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Genoa to Isernia.ExpandLaunch map view
  • Distance: 675 km
  • Duration: 14h 45m

What companies run services between Genoa, Italy and Isernia, Italy?

You can take a train from Genova Brignole to Isernia via Roma Tiburtina in around 7h 19m.

Operators