The average train between Genoa and Isernia takes 14h 45m and the fastest train takes 12h 40m. The train runs, on average, 6 times per week from Genoa to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between Genoa and Isernia. The earliest departure is at 7:12 AM in the morning, and the last departure from Genoa is at 6:42 PM which arrives into Isernia at 7:52 PM. All services require a transfer, and take on average 14h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Genoa to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Genoa to Isernia. However, there are services departing from Genova Brignole station and arriving at Isernia station via Roma Tiburtina station. The journey, including transfers, takes approximately 14h 45m.
Genoa to Isernia train services, operated by Trenitalia Frecce, depart from Genova Brignole station.
Genoa to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Genoa to Isernia train tickets online with Omio.
The distance between Genoa and Isernia is 531.4 km. The road distance is 653 km.
You can take a train from Genova Brignole to Isernia via Roma Tiburtina in around 7h 19m.