Rome2Rio

Portland to St. Louis buses

Find Transport to St. Louis

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The bus between Portland and St. Louis takes 44h 55m. The bus runs, on average, 6 times per week from Portland to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 55m
Duration
2,227 mi
Distance
$462
Average price
6 times a week
Frequency

Portland to St. Louis bus times

Buses run 6 times a week between Portland and St. Louis. The service departs Portland at 9:15 AM in the morning, which arrives into St. Louis at 08:10:00. All services require a transfer at Pasco Bus Stop and take an average of 44h 55m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA44h 55m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA44h 55m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA44h 55m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA44h 55m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA44h 55m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA44h 55m • 2 changes

Frequently asked questions

Want to know about travelling from Portland to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Portland to St. Louis.ExpandLaunch map view
  • Distance: 2,226.8 mi
  • Duration: 44h 55m

What companies run services between Portland, OR, USA and St. Louis, MO, USA?

You can take a bus from Portland Curbside Bus Stop to St Louis Bus Station via Pasco Bus Stop and Denver Union Station in around 45h 25m.

Operators