The average bus between Philadelphia and St. Louis takes 21h 25m and the fastest bus takes 20h 50m. The bus service runs several times per day from Philadelphia to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Philadelphia and St. Louis. The earliest departure is at 3:55 AM at night, and the last departure from Philadelphia is at 5:35 PM which arrives into St. Louis at 3:10 PM. All services run direct with no transfers required, and take on average 21h 25m. The schedules shown below are for the next available departures.
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Want to know about travelling from Philadelphia to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Philadelphia station and arriving at St. Louis station. Services depart 3 times a day, and operate Once daily. The journey takes approximately 21h 25m.
Philadelphia to St. Louis bus services, operated by Greyhound USA, depart from Philadelphia station.
Philadelphia to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Philadelphia to St. Louis bus tickets online with Greyhound USA.
The distance between Philadelphia and St. Louis is 1,300.6 km. The road distance is 1,462 km.
Greyhound USA operates a bus from Philadelphia to St Louis Bus Station 3 times a day. Tickets cost $150–300 and the journey takes 20h 50m.
