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How to get fromMurphysboro to MilwaukeeBy plane, bus, train (Amtrak), car, taxi, or bus (Flixbus, Amtrak, Greyhound)

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There are 10 ways to get from Murphysboro to Milwaukee by plane, bus, train (Amtrak), car, taxi, or bus (Flixbus, Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Williamson County Regional Airport to Chicago O'Hare International Airport, bus

    best
    1. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    4h 37m
    $158–277

  2. Drive to Barkley Regional Airport, fly to Chicago O'Hare International Airport, bus

    cheapest
    1. Drive from Murphysboro to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane plane PAH - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 26m
    $68–339

  3. Bus

    1. Take the bus from Marathon Gas Station - Marion to Water & Chicago - Circle Kbus bus Milwaukee
    8h 4m
    $131–251

  4. Train (Amtrak)

    1. Take the train from Carbondale to Chicago Union Stationtrain train Saluki / ...
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    8h 10m
    $127–263

  5. Drive 419.7 mi

    1. Drive from Murphysboro to Milwaukeecar car 419.7 mi
    7h 18m
    $77–111

  6. Bus to Lambert–St. Louis International Airport, fly to General Mitchell International Airport

    1. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    5h 41m
    $137–824

  7. Taxi to Cape Girardeau Municipal Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the taxi from Murphysboro to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane plane CGI - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 29m
    $191–377

  8. Fly Williamson County Regional Airport to General Mitchell International Airport

    1. Fly from Williamson County Regional Airport (MWA) to General Mitchell International Airport (MKE)plane plane MWA - MKE
    5h 6m
    $232–661

  9. Bus to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    7h 48m
    $308–650

  10. Bus via Chicago

    1. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    11h 51m
    $82–166

Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD) flights

Calendar12Weekly Planes
Duration1h 40mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

What companies run services between Murphysboro, IL, USA and Milwaukee, WI, USA?

Tornado Bus Company operates a bus from Marathon Gas Station - Marion to Water & Chicago - Circle K once daily. Tickets cost $80–190 and the journey takes 7h 35m. Alternatively, you can take a vehicle from Murphysboro to Milwaukee via Carbondale and Chicago Union Station in around 8h 10m.

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