There are 6 ways to get from Murphysboro to Chicago by plane, train (Amtrak), bus (Flixbus), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Williamson County Regional Airport
best- Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)MWA - ORD
2h 48m$111–233Train (Amtrak)
cheapest- Take the train from Carbondale to Chicago Union StationSaluki / ...
5h 41m$59–143Bus (Flixbus)
- Take the bus from Carbondale Intermodal Station to Chicago Bus StationFlixBus N2521
9h 40m$74–143Drive 331.9 mi
- Drive from Murphysboro to Chicago331.9 mi
5h 41m$61–88Taxi to Cape Girardeau Municipal Airport, fly
- Take the taxi from Murphysboro to Cape Girardeau Municipal Airport (CGI)
- Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)CGI - ORD
3h 42m$184–313Drive to Barkley Regional Airport, fly
- Drive from Murphysboro to Barkley Regional Airport (PAH)
- Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)PAH - ORD
3h 58m$256–1,725
Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Murphysboro to Chicago is to drive which costs $60 - $90 and takes 5h 41m.
The fastest way to get from Murphysboro to Chicago is to fly which takes 2h 48m and costs $110 - $240.
The distance between Murphysboro and Chicago is 337 miles. The road distance is 333.9 miles.
The best way to get from Murphysboro to Chicago without a car is to train which takes 5h 41m and costs $55 - $150.
It takes approximately 2h 48m to get from Murphysboro to Chicago, including transfers.
The best way to get from Murphysboro to Chicago is to fly which takes 2h 48m and costs $110 - $240. Alternatively, you can train, which costs $55 - $150 and takes 5h 41m, you could also bus, which costs $70 - $150 and takes 9h 40m.
Yes, the driving distance between Murphysboro to Chicago is 334 miles. It takes approximately 5h 41m to drive from Murphysboro to Chicago.
There are 1237+ hotels available in Chicago.
What companies run services between Murphysboro, IL, USA and Chicago, IL, USA?
Corporate Flight Management Inc flies from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, Amtrak operates a train from Carbondale to Chicago Union Station 3 times a day. Tickets cost $40–120 and the journey takes 5h 30m.
- Website
- contouraviation.com
Flights from Williamson County Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–170
Flights from Cape Girardeau Municipal Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–170
- Website
- united.com
Flights from Barkley Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $40–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Carbondale Intermodal Station to Chicago Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $55–120
- Schedules at
- flixbus.com
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