There are 7 ways to get from Murphysboro to Cincinnati by plane, bus (Amtrak, Flixbus, Greyhound), train, bus, car, taxi, or bus (Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Williamson County Regional Airport
best- Fly from Williamson County Regional Airport (MWA) to Covington (CVG)plane MWA - CVG
5h 18m$271–1,010Drive 322.8 mi
cheapest- Drive from Murphysboro to Cincinnaticar 322.8 mi
5h 57m$59–86Bus
- Take the bus from Carbondale to St. Louisbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Cincinnatibus
10h 50m$85–198Train, bus
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis to Cincinnatibus
14h 49m$99–228Bus to Nashville, fly
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Covington (CVG)plane BNA - CVG
7h 44m$123–667Taxi to Cape Girardeau Municipal Airport, fly
- Take the taxi from Murphysboro to Cape Girardeau Municipal Airport (CGI)taxi
- Fly from Cape Girardeau Municipal Airport (CGI) to Covington (CVG)plane CGI - CVG
7h 10m$359–1,240Bus via Nashville
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
11h 28m$83–208
Williamson County Regional Airport (MWA) to Covington (CVG) flights
Questions & Answers
The cheapest way to get from Murphysboro to Cincinnati is to drive which costs $55 - $85 and takes 5h 57m.
The fastest way to get from Murphysboro to Cincinnati is to fly which takes 5h 18m and costs $270 - $1,100.
The distance between Murphysboro and Cincinnati is 287 miles. The road distance is 324.6 miles.
The best way to get from Murphysboro to Cincinnati without a car is to bus which takes 10h 50m and costs $85 - $200.
It takes approximately 5h 18m to get from Murphysboro to Cincinnati, including transfers.
The best way to get from Murphysboro to Cincinnati is to fly which takes 5h 18m and costs $270 - $1,100. Alternatively, you can bus, which costs $85 - $200 and takes 10h 50m.
Cincinnati is 1h ahead of Murphysboro. It is currently 3:10 AM in Murphysboro and 4:10 AM in Cincinnati.
Yes, the driving distance between Murphysboro to Cincinnati is 325 miles. It takes approximately 5h 57m to drive from Murphysboro to Cincinnati.
There are 465+ hotels available in Cincinnati.
What companies run services between Murphysboro, IL, USA and Cincinnati, OH, USA?
Corporate Flight Management Inc and United Airlines fly from Williamson County Regional Airport (MWA) to Covington (CVG) twice daily. Alternatively, you can take a vehicle from Murphysboro to Cincinnati via Carbondale, St. Louis, St Louis Bus Station, Indianapolis, Illinois St (Greyhound Bus Station), and Indianapolis in around 10h 50m.
- Website
- united.com
Flights from Williamson County Regional Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $220–950
Flights from Cape Girardeau Municipal Airport to Covington via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,100
- Website
- southwest.com
Flights from Nashville to Covington
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $75–550
- Website
- flyfrontier.com
Flights from Cape Girardeau Municipal Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 5h 43m
- When
- Sunday
- Estimated price
- $220–1,100
- Website
- delta.com
Flights from Cape Girardeau Municipal Airport to Covington via Chicago O'Hare, Detroit
- Ave. Duration
- 8h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $300–1,300
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $21–30
- Schedules at
- flixbus.com
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h
- Frequency
- 6 times a week
- Estimated price
- $15–85
- Schedules at
- flixbus.com
- Adult
- $15–85
Bus from Carbondale Intermodal Station to Nashville Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $25–90
- Schedules at
- flixbus.com
- Adult
- $25–90
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
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