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How to get fromMurphysboro to Cincinnatiby bus (Amtrak, Flixbus, Greyhound), train, bus, car, plane, bus (Flixbus, Amtrak) or taxi

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There are 8 ways to get from Murphysboro to Cincinnati by bus (Amtrak, Flixbus, Greyhound), train, bus, car, plane, bus (Flixbus, Amtrak), or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Carbondale to St. Louisbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis to Cincinnatibus bus
    10h 50m
    $84–198

  2. Drive 322.8 mi

    cheapest
    1. Drive from Murphysboro to Cincinnaticar car 322.8 mi
    5h 57m
    $59–86

  3. Train, bus

    1. Take the train from Carbondale to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis to Cincinnatibus bus
    14h 49m
    $99–223

  4. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    8h 24m
    $204–1,063

  5. Bus via Nashville

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville to Louisville, KYbus bus
    3. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    11h 28m
    $88–163

  6. Fly from Williamson County Regional Airport

    1. Fly from Williamson County Regional Airport (MWA) to Covington (CVG)plane plane MWA - CVG
    5h 14m
    $251–1,060

  7. Bus to Nashville, fly

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Covington (CVG)plane plane BNA - CVG
    7h 44m
    $133–672

  8. Taxi to Cape Girardeau Municipal Airport, fly

    1. Take the taxi from Murphysboro to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Covington (CVG)plane plane CGI - CVG
    7h 8m
    $409–1,440

Lambert–St. Louis International Airport (STL) to Covington (CVG) flights

Calendar123Weekly Planes
Duration4h 44mAverage Duration
Ticket$166Cheapest Price
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Questions & Answers

What companies run services between Murphysboro, IL, USA and Cincinnati, OH, USA?

You can take a vehicle from Murphysboro to Cincinnati via Carbondale, St. Louis, St Louis Bus Station, Indianapolis, Illinois St (Greyhound Bus Station), and Indianapolis in around 10h 50m. Alternatively, Corporate Flight Management Inc, United Airlines, and three other airlines fly from Williamson County Regional Airport (MWA) to Covington (CVG) 3 times a day.

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