There are 7 ways to get from Murphysboro to Cincinnati by plane, train, bus, car, bus (Flixbus, Amtrak), or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Williamson County Regional Airport
best- Fly from Williamson County Regional Airport (MWA) to Covington (CVG)plane MWA - CVG
5h 47m$151–660Drive 322.8 mi
cheapest- Drive from Murphysboro to Cincinnaticar 322.8 mi
5h 57m$59–86Train, bus via Dayton
- Take the train from Carbondale to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Cincinnatibus
10h 56m$113–220Bus to Lambert–St. Louis International Airport, fly
- Take the bus from Carbondale to St. Louisbus
- Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane STL - CVG
8h 9m$157–778Bus
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
11h 16m$87–168Train, bus
- Take the train from Carbondale to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus
- Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus
11h 16m$105–258Bus via Newburg
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus
- Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
12h 36m$110–273
Williamson County Regional Airport (MWA) to Covington (CVG) flights
Questions & Answers
The cheapest way to get from Murphysboro to Cincinnati is to drive which costs $55 - $85 and takes 5h 57m.
The fastest way to get from Murphysboro to Cincinnati is to fly which takes 5h 47m and costs $150 - $700.
No, there is no direct bus from Murphysboro station to Cincinnati. However, there are services departing from Carbondale Intermodal Station and arriving at Cincinnati - Downtown via Nashville and Louisville, KY Bus Station. The journey, including transfers, takes approximately 11h 16m.
The distance between Murphysboro and Cincinnati is 287 miles. The road distance is 324.6 miles.
The best way to get from Murphysboro to Cincinnati without a car is to train and bus via Dayton which takes 10h 56m and costs $110 - $220.
It takes approximately 5h 47m to get from Murphysboro to Cincinnati, including transfers.
Murphysboro to Cincinnati bus services, operated by Flixbus USA, depart from Carbondale Intermodal Station.
The best way to get from Murphysboro to Cincinnati is to fly which takes 5h 47m and costs $150 - $700. Alternatively, you can bus, which costs $85 - $170 and takes 11h 16m.
Murphysboro to Cincinnati bus services, operated by Flixbus USA, arrive at Nashville Bus Station.
Cincinnati is 1h ahead of Murphysboro. It is currently 9:23 PM in Murphysboro and 10:23 PM in Cincinnati.
What companies run services between Murphysboro, IL, USA and Cincinnati, OH, USA?
American Airlines and Corporate Flight Management Inc fly from Williamson County Regional Airport (MWA) to Covington (CVG) twice daily. Alternatively, you can take a vehicle from Murphysboro to Cincinnati - Downtown via Carbondale Intermodal Station, Nashville, and Louisville, KY Bus Station in around 11h 16m.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Covington via Detroit
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Covington via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $170–850
Flights from Lambert–St. Louis International Airport to Covington via Minneapolis
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $190–950
- Website
- aa.com
Flights from Williamson County Regional Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $100–850
Flights from Lambert–St. Louis International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 28m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Covington via Charlotte
- Ave. Duration
- 4h 36m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $170–900
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Covington via Nashville
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Covington via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Tuesday to Friday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Carbondale to Champaign-Urbana
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Train from Carbondale to Champaign-Urbana
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Dayton Trotwood Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $15–29
- Website
- https://www.greyhound.com/
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Dayton Trotwood Bus Station to Cincinnati
- Ave. Duration
- 55 min
- Frequency
- 4 times a week
- Estimated price
- $7–13
- Schedules at
- flixbus.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $13–23
- Schedules at
- flixbus.com
Bus from Carbondale Intermodal Station to Nashville Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 5 times a week
- Estimated price
- $29–50
- Schedules at
- flixbus.com
Bus from Carbondale Intermodal Station to Nashville Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 5 times a week
- Estimated price
- $29–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
Bus from Indianapolis, IN to Greyhound Station Cincinnati
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $13–50
- Website
- https://baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KY
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a week
- Estimated price
- $50–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $50–150
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More Questions & Answers
Yes, the driving distance between Murphysboro to Cincinnati is 325 miles. It takes approximately 5h 57m to drive from Murphysboro to Cincinnati.
There are 655+ hotels available in Cincinnati.













