There are 9 ways to get from Micco to Florida Keys by bus (Greyhound), car, shuttle, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Fort Pierce South
best- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to Miami Airport
- Take the bus from Miami Airport Station to Big Pine Key
10h 27m$83–185Drive 298.5 mi
cheapest- Drive from Micco to Florida Keys298.5 mi
5h 53m$55–79Shuttle to Orlando, fly to Key West International Airport
- Take a shuttle bus from Sebastian, FL - BP to Orlando Airport
- Fly from Orlando (MCO) to Key West International Airport (EYW)MCO - EYW
6h 45m$229–520Bus, train
- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to West Palm Beach, FL
- Take the train from West Palm Beach Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
11h 18m$82–186Bus, shuttle
- Take the bus from Sebastian to Miami Airport StationGreyhound US0710s
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
11h 19m$189–280Bus (Greyhound)
- Take the bus from Sebastian to Miami Airport StationGreyhound US0710s
- Take the bus from Miami Airport Station to Big Pine KeyGreyhound US0720s
11h 36m$81–140Shuttle to Orlando, fly to Miami International Airport, shuttle
- Take a shuttle bus from Sebastian, FL - BP to Orlando Airport
- Fly from Orlando (MCO) to Miami International Airport (MIA)MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 19m$299–615Bus, bus to Fort Lauderdale–Hollywood International Airport, fly to Key West International Airport
- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to Fort Lauderdale Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Key West International Airport (EYW)FLL - EYW
8h 18m$154–595Bus, bus to Miami International Airport, fly to Key West International Airport
- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to Miami Airport
- Fly from Miami International Airport (MIA) to Key West International Airport (EYW)MIA - EYW
9h 13m$256–760
Orlando (MCO) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Micco to Florida Keys is to drive which costs $50 - $80 and takes 5h 53m.
The fastest way to get from Micco to Florida Keys is to drive which takes 5h 53m and costs $50 - $80.
The distance between Micco and Florida Keys is 312 miles. The road distance is 300.2 miles.
The best way to get from Micco to Florida Keys without a car is to bus via Fort Pierce South which takes 10h 27m and costs $80 - $190.
It takes approximately 10h 27m to get from Micco to Florida Keys, including transfers.
Yes, the driving distance between Micco to Florida Keys is 300 miles. It takes approximately 5h 53m to drive from Micco to Florida Keys.
There are 792+ hotels available in Florida Keys.
What companies run services between Micco, FL, USA and Florida Keys, FL, USA?
You can take a vehicle from Micco to Florida Keys via Sebastian, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 10h 27m.
- Website
- aa.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $30–220
Flights from Miami International Airport to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $40–290
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $30–220
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- spirit.com
Flights from Fort Lauderdale–Hollywood International Airport to Key West International Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- $50–230
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Sebastian to Fort Pierce
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $22–50
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- https://www.greyhound.com/
Bus from Fort Pierce to West Palm Beach, FL
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $18–26
- Website
- https://www.greyhound.com/
Bus from Sebastian to Miami Airport Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Pierce to Miami Airport
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $15–65
- Website
- https://www.redcoachusa.com
- Web
- $15–65
Bus from Fort Pierce to West Palm Beach, FL
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- $9–55
- Website
- https://www.redcoachusa.com
- Web
- $9–55
Bus from Fort Pierce to Fort Lauderdale Airport
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–60
- Website
- https://www.redcoachusa.com
- Web
- $13–60
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Sebastian, FL - BP to Orlando Airport
- Ave. Duration
- 1h 22m
- Frequency
- 4 times a day
- Estimated price
- $60–75
- Schedules at
- smartshuttleline.com
- one passenger
- $60–75
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide











